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- W2803773054 abstract "Different synthetic strategies for the formation of contact active antimicrobial materials utilizing covalent linkage of quaternary ammonium compounds (QACs) were reviewed. There is a demand to find methods that will prevent bacterial fouling without the release of antimicrobial agents, because biocides cause environment pollution and promote the development of bacteria resistance mechanisms. The contact active antimicrobial surfaces may provide a useful tool for this purpose. The covalent surface grafting of QACs seems to be a feasible and promising approach for the formation of safe and effective antimicrobial materials that could be utilized for medical devices, food industry, water treatment systems and other applications. This manuscript reviews covalent attachment of QACs to form contact active antimicrobial materials based on glass, metals, synthetic and natural polymers. The review emphasizes the description of different synthetic methods that are used for the covalent linkage. Direct covalent linkage of QACs to the material surfaces, a linkage via auxiliary nanoparticles (NPs), or spacers, controlled radical polymerization techniques and a linkage to pre-activated surfaces are discussed. The physico-chemical properties and biological activity of the modified surfaces are also described. This review does not cover non-covalent grafting of QACs and incorporation of QACs into a bulk material." @default.
- W2803773054 created "2018-06-01" @default.
- W2803773054 creator A5054840397 @default.
- W2803773054 creator A5074657157 @default.
- W2803773054 date "2018-09-01" @default.
- W2803773054 modified "2023-09-27" @default.
- W2803773054 title "Formation of contact active antimicrobial surfaces by covalent grafting of quaternary ammonium compounds" @default.
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- W2803773054 doi "https://doi.org/10.1016/j.colsurfb.2018.04.065" @default.
- W2803773054 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29778035" @default.
- W2803773054 hasPublicationYear "2018" @default.
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