FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804057239> ?p ?o ?g. }

• W2804057239 abstract "Chemical alkylation of DNA produces potentially toxic and mutagenic damage such as O 6 ‐alkylguanine ( O 6 ‐alkylG) adducts. Non‐natural nucleoside analogues that pair with DNA adducts provide a potential basis for studying damaged DNA . Herein, we evaluated the base pairing properties of elongated nucleoside analogues containing napthalene‐derived tricyclic nucleobases as DNA adduct‐pairing nucleoside analogues in DNA hybridization probes. DNA duplex melting studies revealed that the elongated nucleoside analogs formed more stable base pairs opposite O 6 ‐alkylG than G and were better able to distinguish between G, O 6 ‐alkylG, and an abasic site than any previously described nucleoside analogue. DNA duplexes containing an elongated base analogue exhibited different fluorescence intensities when paired opposite O 6 ‐alkylG vs . G or abasic sites. Their selectivity for stabilizing alkylated DNA make the elongated hydrophobic base analogues improved candidates for incorporating into DNA hybridization probes targeting O 6 ‐alkylG." @default.
• W2804057239 created "2018-06-01" @default.
• W2804057239 creator A5020186448 @default.
• W2804057239 creator A5064386265 @default.
• W2804057239 creator A5069168544 @default.
• W2804057239 creator A5070495967 @default.
• W2804057239 creator A5075042199 @default.
• W2804057239 creator A5077410840 @default.
• W2804057239 creator A5078822971 @default.
• W2804057239 creator A5086091710 @default.
• W2804057239 date "2018-06-21" @default.
• W2804057239 modified "2023-09-25" @default.
• W2804057239 title "Fluorescent Nucleobase Analogues with Extended Pi Surfaces Stabilize DNA Duplexes Containing <i>O</i> ⁶ -Alkylguanine Adducts" @default.
• W2804057239 cites W1571934973 @default.
• W2804057239 cites W1791564905 @default.
• W2804057239 cites W1963703989 @default.
• W2804057239 cites W1968000756 @default.
• W2804057239 cites W1971387551 @default.
• W2804057239 cites W1972228600 @default.
• W2804057239 cites W1974955901 @default.
• W2804057239 cites W1977996638 @default.
• W2804057239 cites W1978649037 @default.
• W2804057239 cites W1980926572 @default.
• W2804057239 cites W1981033460 @default.
• W2804057239 cites W1988006430 @default.
• W2804057239 cites W1989955252 @default.
• W2804057239 cites W1991330225 @default.
• W2804057239 cites W1991898744 @default.
• W2804057239 cites W1996080607 @default.
• W2804057239 cites W2001676393 @default.
• W2804057239 cites W2003610520 @default.
• W2804057239 cites W2003956015 @default.
• W2804057239 cites W2005757429 @default.
• W2804057239 cites W2011700719 @default.
• W2804057239 cites W2014118668 @default.
• W2804057239 cites W2015927837 @default.
• W2804057239 cites W2016066488 @default.
• W2804057239 cites W2017665581 @default.
• W2804057239 cites W2018433273 @default.
• W2804057239 cites W2026312334 @default.
• W2804057239 cites W2032990719 @default.
• W2804057239 cites W2037017264 @default.
• W2804057239 cites W2038271017 @default.
• W2804057239 cites W2043981588 @default.
• W2804057239 cites W2047566085 @default.
• W2804057239 cites W2048631643 @default.
• W2804057239 cites W2050480410 @default.
• W2804057239 cites W2056570394 @default.
• W2804057239 cites W2057701529 @default.
• W2804057239 cites W2065317370 @default.
• W2804057239 cites W2067280604 @default.
• W2804057239 cites W2070830262 @default.
• W2804057239 cites W2082908643 @default.
• W2804057239 cites W2088979606 @default.
• W2804057239 cites W2091960667 @default.
• W2804057239 cites W2097111597 @default.
• W2804057239 cites W2100793313 @default.
• W2804057239 cites W2126935270 @default.
• W2804057239 cites W2129757655 @default.
• W2804057239 cites W2131615281 @default.
• W2804057239 cites W2141883905 @default.
• W2804057239 cites W2142589895 @default.
• W2804057239 cites W2147993766 @default.
• W2804057239 cites W2148549708 @default.
• W2804057239 cites W2148873028 @default.
• W2804057239 cites W2151020295 @default.
• W2804057239 cites W2152304921 @default.
• W2804057239 cites W2157867429 @default.
• W2804057239 cites W2167713837 @default.
• W2804057239 cites W2168194369 @default.
• W2804057239 cites W2168921143 @default.
• W2804057239 cites W2312431898 @default.
• W2804057239 cites W2319729542 @default.
• W2804057239 cites W2324698777 @default.
• W2804057239 cites W2329888557 @default.
• W2804057239 cites W2404280981 @default.
• W2804057239 cites W2426621117 @default.
• W2804057239 cites W2549942018 @default.
• W2804057239 cites W2618850540 @default.
• W2804057239 cites W2727349514 @default.
• W2804057239 cites W2735030099 @default.
• W2804057239 cites W4248746261 @default.
• W2804057239 cites W4250988022 @default.
• W2804057239 doi "https://doi.org/10.1002/hlca.201800066" @default.
• W2804057239 hasPublicationYear "2018" @default.
• W2804057239 type Work @default.
• W2804057239 sameAs 2804057239 @default.
• W2804057239 citedByCount "4" @default.
• W2804057239 countsByYear W28040572392018 @default.
• W2804057239 countsByYear W28040572392019 @default.
• W2804057239 countsByYear W28040572392020 @default.
• W2804057239 countsByYear W28040572392022 @default.
• W2804057239 crossrefType "journal-article" @default.
• W2804057239 hasAuthorship W2804057239A5020186448 @default.
• W2804057239 hasAuthorship W2804057239A5064386265 @default.
• W2804057239 hasAuthorship W2804057239A5069168544 @default.
• W2804057239 hasAuthorship W2804057239A5070495967 @default.
• W2804057239 hasAuthorship W2804057239A5075042199 @default.
• W2804057239 hasAuthorship W2804057239A5077410840 @default.
• W2804057239 hasAuthorship W2804057239A5078822971 @default.

• next