Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804065022> ?p ?o ?g. }
- W2804065022 endingPage "109" @default.
- W2804065022 startingPage "93" @default.
- W2804065022 abstract "Carbon nanotubes (CNTs) have shown potential applications in neuroscience as growth substrates owing to their numerous unique properties. However, a key concern in the fabrication of homogeneous composites is the serious aggregation of CNTs during incorporation into the biomaterial matrix. Moreover, the regulation mechanism of CNT-based substrates on neural differentiation remains unclear. Here, a novel strategy was introduced for the construction of CNT nanocomposites via layer-by-layer assembly of negatively charged multi-walled CNTs and positively charged poly(dimethyldiallylammonium chloride). Results demonstrated that the CNT-multilayered nanocomposites provided a potent regulatory signal over neural stem cells (NSCs), including cell adhesion, viability, differentiation, neurite outgrowth, and electrophysiological maturation of NSC-derived neurons. Importantly, the dynamic molecular mechanisms in the NSC differentiation involved the integrin-mediated interactions between NSCs and CNT multilayers, thereby activating focal adhesion kinase, subsequently triggering downstream signaling events to regulate neuronal differentiation and synapse formation. This study provided insights for future applications of CNT-multilayered nanomaterials in neural fields as potent modulators of stem cell behavior." @default.
- W2804065022 created "2018-06-01" @default.
- W2804065022 creator A5036974410 @default.
- W2804065022 creator A5042577296 @default.
- W2804065022 creator A5061396145 @default.
- W2804065022 creator A5066382350 @default.
- W2804065022 creator A5066528324 @default.
- W2804065022 creator A5074047749 @default.
- W2804065022 creator A5076636647 @default.
- W2804065022 creator A5077698461 @default.
- W2804065022 creator A5078850185 @default.
- W2804065022 creator A5085911348 @default.
- W2804065022 creator A5089711006 @default.
- W2804065022 date "2018-08-01" @default.
- W2804065022 modified "2023-10-18" @default.
- W2804065022 title "Carbon nanotube multilayered nanocomposites as multifunctional substrates for actuating neuronal differentiation and functions of neural stem cells" @default.
- W2804065022 cites W1589010135 @default.
- W2804065022 cites W1697944648 @default.
- W2804065022 cites W1964380577 @default.
- W2804065022 cites W1965306647 @default.
- W2804065022 cites W1965933207 @default.
- W2804065022 cites W1966296130 @default.
- W2804065022 cites W1968388250 @default.
- W2804065022 cites W1970037077 @default.
- W2804065022 cites W1970074493 @default.
- W2804065022 cites W1973757009 @default.
- W2804065022 cites W1977656622 @default.
- W2804065022 cites W1977680780 @default.
- W2804065022 cites W1978840211 @default.
- W2804065022 cites W1982082415 @default.
- W2804065022 cites W1984362646 @default.
- W2804065022 cites W1989856919 @default.
- W2804065022 cites W1992597201 @default.
- W2804065022 cites W1994041495 @default.
- W2804065022 cites W2011448168 @default.
- W2804065022 cites W2012702929 @default.
- W2804065022 cites W2013260733 @default.
- W2804065022 cites W2014949837 @default.
- W2804065022 cites W2016894758 @default.
- W2804065022 cites W2018083126 @default.
- W2804065022 cites W2019043097 @default.
- W2804065022 cites W2019116670 @default.
- W2804065022 cites W2019637120 @default.
- W2804065022 cites W2030496781 @default.
- W2804065022 cites W2037072031 @default.
- W2804065022 cites W2037274004 @default.
- W2804065022 cites W2039269764 @default.
- W2804065022 cites W2046028156 @default.
- W2804065022 cites W2047994780 @default.
- W2804065022 cites W2049543696 @default.
- W2804065022 cites W2054179928 @default.
- W2804065022 cites W2057071025 @default.
- W2804065022 cites W2059553654 @default.
- W2804065022 cites W2059743066 @default.
- W2804065022 cites W2061695565 @default.
- W2804065022 cites W2065950646 @default.
- W2804065022 cites W2067127980 @default.
- W2804065022 cites W2068590879 @default.
- W2804065022 cites W2070372593 @default.
- W2804065022 cites W2073371696 @default.
- W2804065022 cites W2074947593 @default.
- W2804065022 cites W2075491707 @default.
- W2804065022 cites W2076662092 @default.
- W2804065022 cites W2077517942 @default.
- W2804065022 cites W2079294719 @default.
- W2804065022 cites W2081892717 @default.
- W2804065022 cites W2081924426 @default.
- W2804065022 cites W2090304430 @default.
- W2804065022 cites W2094134670 @default.
- W2804065022 cites W2095254294 @default.
- W2804065022 cites W2096589146 @default.
- W2804065022 cites W2103793253 @default.
- W2804065022 cites W2104412337 @default.
- W2804065022 cites W2105973849 @default.
- W2804065022 cites W2107919129 @default.
- W2804065022 cites W2109142306 @default.
- W2804065022 cites W2110282630 @default.
- W2804065022 cites W2112696319 @default.
- W2804065022 cites W2118948952 @default.
- W2804065022 cites W2118977349 @default.
- W2804065022 cites W2126496496 @default.
- W2804065022 cites W2134418903 @default.
- W2804065022 cites W2142998520 @default.
- W2804065022 cites W2145295565 @default.
- W2804065022 cites W2146516445 @default.
- W2804065022 cites W2157905636 @default.
- W2804065022 cites W2170252500 @default.
- W2804065022 cites W2170258102 @default.
- W2804065022 cites W2172249996 @default.
- W2804065022 cites W2291437693 @default.
- W2804065022 cites W2316005576 @default.
- W2804065022 cites W2319669589 @default.
- W2804065022 cites W2322562148 @default.
- W2804065022 cites W2470594278 @default.
- W2804065022 cites W2508248062 @default.
- W2804065022 cites W2518889419 @default.
- W2804065022 cites W2548042609 @default.
- W2804065022 cites W2552732878 @default.