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• W2804239408 abstract "In this paper, we present a mathematical model at the cellular level of the tumour-immune competition mediated by the cytokines. The model consists of a system of nonlinear differential equations describing the intracellular interactions between the tumour and the immune cells in the presence of the cytokines. A detailed phenomenological description of the model based on the kinetic theory for active particle approach is carried out to formulate the model. Well-posedness is presented to establish local and global existence. Numerical simulations are addressed to show how initial conditions and model parameters influence the output of the model. Under a suitable choice of the model's key parameters and the cytokines' initial activation levels, the simulation results show that the activated immune system is able to achieve a total elimination of the cancer cells." @default.
• W2804239408 created "2018-06-01" @default.
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• W2804239408 date "2018-05-14" @default.
• W2804239408 modified "2023-09-25" @default.
• W2804239408 title "Activation of the immune response by cytokines and its effect on tumour cells: a mathematical model" @default.
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• W2804239408 doi "https://doi.org/10.1080/23737867.2018.1468725" @default.
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