Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804281454> ?p ?o ?g. }
- W2804281454 abstract "Abstract Neutropenic enterocolitis (NE) is a diagnostic and therapeutic challenge associated with high mortality rates, with controversial opinions on its optimal management. Physicians are usually reluctant to select surgery as the first-choice treatment, concerns being raised regarding the potential risks associated with abdominal surgery during neutropenia. Nevertheless, no published studies comforted this idea, literature is scarce and surgery has never been compared to medical treatment. This review and meta-analysis aimed to determine the prognostic impact of abdominal surgery on outcome of neutropenic cancer patients presenting with NE, versus medical conservative treatment. This meta-analysis included studies analyzing cancer patients presenting with NE, treated with surgical or medical treatment, searched by PubMed and Cochrane databases (1983–2016), according to PRISMA recommendations. The endpoint was hospital mortality. Fixed-effects models were used. The meta-analysis included 20 studies (385 patients). Overall estimated mortality was 42.2% (95% CI = 40.2–44.2). Abdominal surgery was associated with a favorable outcome with an OR of 0.41 (95% CI = 0.23–0.74; p = 0.003). Pre-defined subgroups analysis showed that neither period of admission, underlying malignancy nor neutropenia during the surgical procedure, influenced this result. Surgery was not associated with an excess risk of mortality compared to medical treatment. Defining the optimal indications of surgical treatment is needed. Trial registration PROSPERO CRD42016048952" @default.
- W2804281454 created "2018-06-01" @default.
- W2804281454 creator A5011627688 @default.
- W2804281454 creator A5013313535 @default.
- W2804281454 creator A5031014988 @default.
- W2804281454 creator A5035050483 @default.
- W2804281454 creator A5040520388 @default.
- W2804281454 creator A5049257648 @default.
- W2804281454 creator A5054012129 @default.
- W2804281454 creator A5054312259 @default.
- W2804281454 creator A5055027274 @default.
- W2804281454 creator A5072399565 @default.
- W2804281454 creator A5073088328 @default.
- W2804281454 creator A5076578951 @default.
- W2804281454 date "2018-04-19" @default.
- W2804281454 modified "2023-10-11" @default.
- W2804281454 title "The prognostic impact of abdominal surgery in cancer patients with neutropenic enterocolitis: a systematic review and meta-analysis, on behalf the Groupe de Recherche en Réanimation Respiratoire du patient d’Onco-Hématologie (GRRR-OH)" @default.
- W2804281454 cites W1481996328 @default.
- W2804281454 cites W1483070257 @default.
- W2804281454 cites W1494690844 @default.
- W2804281454 cites W1604525517 @default.
- W2804281454 cites W1853332726 @default.
- W2804281454 cites W1964569052 @default.
- W2804281454 cites W1970220060 @default.
- W2804281454 cites W1973693542 @default.
- W2804281454 cites W1979423827 @default.
- W2804281454 cites W1983820699 @default.
- W2804281454 cites W1985911341 @default.
- W2804281454 cites W1989546130 @default.
- W2804281454 cites W1997571080 @default.
- W2804281454 cites W2000230892 @default.
- W2804281454 cites W2005164182 @default.
- W2804281454 cites W2006394624 @default.
- W2804281454 cites W2007689771 @default.
- W2804281454 cites W2011528582 @default.
- W2804281454 cites W2011623743 @default.
- W2804281454 cites W2011723488 @default.
- W2804281454 cites W2012107441 @default.
- W2804281454 cites W2022961067 @default.
- W2804281454 cites W2026071934 @default.
- W2804281454 cites W2033046938 @default.
- W2804281454 cites W2044762547 @default.
- W2804281454 cites W2061029780 @default.
- W2804281454 cites W2061863558 @default.
- W2804281454 cites W2071342876 @default.
- W2804281454 cites W2073411333 @default.
- W2804281454 cites W2080956823 @default.
- W2804281454 cites W2082399773 @default.
- W2804281454 cites W2091339619 @default.
- W2804281454 cites W2096598041 @default.
- W2804281454 cites W2102852047 @default.
- W2804281454 cites W2102891951 @default.
- W2804281454 cites W2104778351 @default.
- W2804281454 cites W2107661846 @default.
- W2804281454 cites W2109635036 @default.
- W2804281454 cites W2123859227 @default.
- W2804281454 cites W2128029799 @default.
- W2804281454 cites W2132431829 @default.
- W2804281454 cites W2138000143 @default.
- W2804281454 cites W2142195688 @default.
- W2804281454 cites W2146049424 @default.
- W2804281454 cites W2147787450 @default.
- W2804281454 cites W2156098321 @default.
- W2804281454 cites W2156546371 @default.
- W2804281454 cites W2159473962 @default.
- W2804281454 cites W2160691650 @default.
- W2804281454 cites W2161251669 @default.
- W2804281454 cites W2169205464 @default.
- W2804281454 cites W2322237054 @default.
- W2804281454 cites W2401986221 @default.
- W2804281454 cites W2406391698 @default.
- W2804281454 cites W2412285156 @default.
- W2804281454 cites W2412741596 @default.
- W2804281454 cites W2418786009 @default.
- W2804281454 cites W2434863792 @default.
- W2804281454 cites W2442246762 @default.
- W2804281454 cites W246286872 @default.
- W2804281454 cites W2518864633 @default.
- W2804281454 cites W2521686801 @default.
- W2804281454 cites W2588681363 @default.
- W2804281454 cites W2593561529 @default.
- W2804281454 cites W2789320521 @default.
- W2804281454 cites W3022903699 @default.
- W2804281454 cites W4285719527 @default.
- W2804281454 cites W4294215472 @default.
- W2804281454 cites W4300444657 @default.
- W2804281454 cites W5274588 @default.
- W2804281454 cites W6717101 @default.
- W2804281454 doi "https://doi.org/10.1186/s13613-018-0394-6" @default.
- W2804281454 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5908777" @default.
- W2804281454 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29675758" @default.
- W2804281454 hasPublicationYear "2018" @default.
- W2804281454 type Work @default.
- W2804281454 sameAs 2804281454 @default.
- W2804281454 citedByCount "20" @default.
- W2804281454 countsByYear W28042814542018 @default.
- W2804281454 countsByYear W28042814542019 @default.
- W2804281454 countsByYear W28042814542020 @default.
- W2804281454 countsByYear W28042814542021 @default.
- W2804281454 countsByYear W28042814542022 @default.