FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804334904> ?p ?o ?g. }

• W2804334904 endingPage "398" @default.
• W2804334904 startingPage "390" @default.
• W2804334904 abstract "Summer mortality syndrome is one of the most serious issue for Marsupenaeus japonicus aquaculture in China. Since it causes massive economic loss and threatens sustainability of M. japonicus aquaculture industry, thus, there is an urgent desire to reveal the heat stress-host interactions mechanisms that lead to mass mortalities of M. japonicus in hot summer months. MicroRNAs (miRNAs) are small noncoding RNAs that involved in regulation of diverse biological processes, including stress and immune response, and might serve as potential regulators in the heat stress-host interactions. In the present study, miRNAs with heat stress responsive and immune properties were identified and characterized in M. japonicus by small RNA sequencing and bioinformatics analysis. In total, 79 host miRNAs were identified, among which 15 miRNAs were differentially expressed in response to heat stress. Target genes prediction and function annotation revealed that a variety of host cellular processes, such as signal transduction, transcription, anti-stress response, ribosomal biogenesis, lipid metabolism, cytoskeleton, etc, were potentially subject to miRNA-mediated regulation in response to heat stress. Furthermore, a total of 30 host miRNAs that potentially involved in interaction with white spot syndrome virus (WSSV) were obtained via predicting and analyzing the target genes from WSSV. The results showed that a batch of WSSV genes that code for structural proteins and enzymes that are essential for WSSV infection and proliferation, such as envelope proteins, capsid proteins, immediate-early proteins, collagen-like protein, protein kinase, thymidylate synthetase, TATA-box bind protein, etc, were predicted to be targeted by host miRNAs. Several of the host miRNAs with predicted antiviral capacity were down-regulated under heat stress, indicating a repression of host miRNA-mediated antiviral immune response. This study highlighted the essential roles of host miRNAs in the heat stress-host interactions and provided valuable information for further investigation on the mechanism of miRNA-mediated heat stress and immune response of shrimp." @default.
• W2804334904 created "2018-06-01" @default.
• W2804334904 creator A5008924675 @default.
• W2804334904 creator A5041505936 @default.
• W2804334904 creator A5042241049 @default.
• W2804334904 creator A5059483665 @default.
• W2804334904 creator A5071642585 @default.
• W2804334904 date "2018-10-01" @default.
• W2804334904 modified "2023-09-24" @default.
• W2804334904 title "Identification of microRNAs with heat stress responsive and immune properties in Marsupenaeus japonicus based on next-generation sequencing and bioinformatics analysis: Essential regulators in the heat stress-host interactions" @default.
• W2804334904 cites W144423133 @default.
• W2804334904 cites W1553418250 @default.
• W2804334904 cites W1748513624 @default.
• W2804334904 cites W1892182006 @default.
• W2804334904 cites W1968631483 @default.
• W2804334904 cites W1970541687 @default.
• W2804334904 cites W1973728462 @default.
• W2804334904 cites W1976840283 @default.
• W2804334904 cites W1978772332 @default.
• W2804334904 cites W1979508894 @default.
• W2804334904 cites W1980269624 @default.
• W2804334904 cites W1980445909 @default.
• W2804334904 cites W1986448383 @default.
• W2804334904 cites W1988097700 @default.
• W2804334904 cites W1989707466 @default.
• W2804334904 cites W1993403278 @default.
• W2804334904 cites W1994816216 @default.
• W2804334904 cites W1995654442 @default.
• W2804334904 cites W1998167027 @default.
• W2804334904 cites W2004762438 @default.
• W2804334904 cites W2021387021 @default.
• W2804334904 cites W2021524989 @default.
• W2804334904 cites W2025169368 @default.
• W2804334904 cites W2028994878 @default.
• W2804334904 cites W2032400163 @default.
• W2804334904 cites W2032427971 @default.
• W2804334904 cites W2033130909 @default.
• W2804334904 cites W2036158295 @default.
• W2804334904 cites W2044832480 @default.
• W2804334904 cites W2052818151 @default.
• W2804334904 cites W2063530272 @default.
• W2804334904 cites W2071634388 @default.
• W2804334904 cites W2074904925 @default.
• W2804334904 cites W2084292012 @default.
• W2804334904 cites W2084739956 @default.
• W2804334904 cites W2086415805 @default.
• W2804334904 cites W2088855322 @default.
• W2804334904 cites W2089465951 @default.
• W2804334904 cites W2094253263 @default.
• W2804334904 cites W2097617110 @default.
• W2804334904 cites W2099210988 @default.
• W2804334904 cites W2105679485 @default.
• W2804334904 cites W2107277218 @default.
• W2804334904 cites W2118579624 @default.
• W2804334904 cites W2121599969 @default.
• W2804334904 cites W2125468282 @default.
• W2804334904 cites W2130305733 @default.
• W2804334904 cites W2152979236 @default.
• W2804334904 cites W2153283433 @default.
• W2804334904 cites W2155791783 @default.
• W2804334904 cites W2162674813 @default.
• W2804334904 cites W2164154631 @default.
• W2804334904 cites W2166748873 @default.
• W2804334904 cites W2171719160 @default.
• W2804334904 cites W2178113031 @default.
• W2804334904 cites W2190960788 @default.
• W2804334904 cites W2278469987 @default.
• W2804334904 cites W2293691477 @default.
• W2804334904 cites W2295914061 @default.
• W2804334904 cites W2346722286 @default.
• W2804334904 cites W2520401024 @default.
• W2804334904 cites W2547354657 @default.
• W2804334904 cites W2589950959 @default.
• W2804334904 cites W2592871562 @default.
• W2804334904 cites W2604135852 @default.
• W2804334904 cites W2619153064 @default.
• W2804334904 cites W2626184633 @default.
• W2804334904 cites W2741900361 @default.
• W2804334904 cites W2744021459 @default.
• W2804334904 cites W2763119360 @default.
• W2804334904 cites W2782242238 @default.
• W2804334904 cites W2789487174 @default.
• W2804334904 cites W4205090231 @default.
• W2804334904 cites W4236865751 @default.
• W2804334904 doi "https://doi.org/10.1016/j.fsi.2018.05.030" @default.
• W2804334904 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29778844" @default.
• W2804334904 hasPublicationYear "2018" @default.
• W2804334904 type Work @default.
• W2804334904 sameAs 2804334904 @default.
• W2804334904 citedByCount "13" @default.
• W2804334904 countsByYear W28043349042019 @default.
• W2804334904 countsByYear W28043349042020 @default.
• W2804334904 countsByYear W28043349042021 @default.
• W2804334904 countsByYear W28043349042022 @default.
• W2804334904 countsByYear W28043349042023 @default.
• W2804334904 crossrefType "journal-article" @default.
• W2804334904 hasAuthorship W2804334904A5008924675 @default.
• W2804334904 hasAuthorship W2804334904A5041505936 @default.

• next