Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804367002> ?p ?o ?g. }
- W2804367002 abstract "Abstract Absence epilepsy is a common childhood disorder featuring frequent cortical spike-wave seizures with a loss of awareness and behavior. Using the calcium indicator GCaMP6 with in vivo 2-photon cellular microscopy and simultaneous electrocorticography, we examined the collective activity profiles of individual neurons and surrounding neuropil across all layers in V1 during spike-wave seizure activity over prolonged periods in stargazer mice. We show that most (~80%) neurons in all cortical layers reduce their activity during seizures, whereas a smaller pool activates or remains neutral. Unexpectedly, ictal participation of identified single-unit activity is not fixed, but fluctuates on a flexible time scale from seizure to seizure. Pairwise correlation analysis of calcium activity reveals a surprising lack of synchrony among neurons and neuropil patches in all layers during seizures. Our results demonstrate asynchronous suppression of visual cortex during absence seizures, with potential implications for understanding cortical network function during EEG states of reduced awareness." @default.
- W2804367002 created "2018-06-01" @default.
- W2804367002 creator A5009348288 @default.
- W2804367002 creator A5012194422 @default.
- W2804367002 creator A5022338498 @default.
- W2804367002 creator A5042392992 @default.
- W2804367002 date "2018-05-16" @default.
- W2804367002 modified "2023-10-11" @default.
- W2804367002 title "Asynchronous suppression of visual cortex during absence seizures in stargazer mice" @default.
- W2804367002 cites W1546235751 @default.
- W2804367002 cites W1583975049 @default.
- W2804367002 cites W1604724533 @default.
- W2804367002 cites W1889678891 @default.
- W2804367002 cites W1972869628 @default.
- W2804367002 cites W1978824962 @default.
- W2804367002 cites W1982388037 @default.
- W2804367002 cites W1985000113 @default.
- W2804367002 cites W1985014120 @default.
- W2804367002 cites W1987777969 @default.
- W2804367002 cites W1988787855 @default.
- W2804367002 cites W2010114799 @default.
- W2804367002 cites W2012491533 @default.
- W2804367002 cites W2014059618 @default.
- W2804367002 cites W2032723117 @default.
- W2804367002 cites W2056571308 @default.
- W2804367002 cites W2061606858 @default.
- W2804367002 cites W2063198621 @default.
- W2804367002 cites W2066096726 @default.
- W2804367002 cites W2067474937 @default.
- W2804367002 cites W2074967846 @default.
- W2804367002 cites W2081321639 @default.
- W2804367002 cites W2089513832 @default.
- W2804367002 cites W2095741293 @default.
- W2804367002 cites W2099111195 @default.
- W2804367002 cites W2111998656 @default.
- W2804367002 cites W2120176125 @default.
- W2804367002 cites W2122955029 @default.
- W2804367002 cites W2128105404 @default.
- W2804367002 cites W2135266824 @default.
- W2804367002 cites W2142686118 @default.
- W2804367002 cites W2145242428 @default.
- W2804367002 cites W2145700801 @default.
- W2804367002 cites W2146282734 @default.
- W2804367002 cites W2152230432 @default.
- W2804367002 cites W2171332611 @default.
- W2804367002 cites W22772606 @default.
- W2804367002 cites W2294653186 @default.
- W2804367002 cites W2411528277 @default.
- W2804367002 cites W2549946685 @default.
- W2804367002 cites W2732455748 @default.
- W2804367002 doi "https://doi.org/10.1038/s41467-018-04349-8" @default.
- W2804367002 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5955878" @default.
- W2804367002 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29769525" @default.
- W2804367002 hasPublicationYear "2018" @default.
- W2804367002 type Work @default.
- W2804367002 sameAs 2804367002 @default.
- W2804367002 citedByCount "27" @default.
- W2804367002 countsByYear W28043670022019 @default.
- W2804367002 countsByYear W28043670022020 @default.
- W2804367002 countsByYear W28043670022021 @default.
- W2804367002 countsByYear W28043670022022 @default.
- W2804367002 countsByYear W28043670022023 @default.
- W2804367002 crossrefType "journal-article" @default.
- W2804367002 hasAuthorship W2804367002A5009348288 @default.
- W2804367002 hasAuthorship W2804367002A5012194422 @default.
- W2804367002 hasAuthorship W2804367002A5022338498 @default.
- W2804367002 hasAuthorship W2804367002A5042392992 @default.
- W2804367002 hasBestOaLocation W28043670021 @default.
- W2804367002 hasConcept C126322002 @default.
- W2804367002 hasConcept C15744967 @default.
- W2804367002 hasConcept C169760540 @default.
- W2804367002 hasConcept C17755696 @default.
- W2804367002 hasConcept C2776032975 @default.
- W2804367002 hasConcept C2777348757 @default.
- W2804367002 hasConcept C2777831001 @default.
- W2804367002 hasConcept C2778186239 @default.
- W2804367002 hasConcept C2779345533 @default.
- W2804367002 hasConcept C2780117969 @default.
- W2804367002 hasConcept C2780196419 @default.
- W2804367002 hasConcept C519063684 @default.
- W2804367002 hasConcept C522805319 @default.
- W2804367002 hasConcept C529278444 @default.
- W2804367002 hasConcept C71924100 @default.
- W2804367002 hasConcept C86803240 @default.
- W2804367002 hasConceptScore W2804367002C126322002 @default.
- W2804367002 hasConceptScore W2804367002C15744967 @default.
- W2804367002 hasConceptScore W2804367002C169760540 @default.
- W2804367002 hasConceptScore W2804367002C17755696 @default.
- W2804367002 hasConceptScore W2804367002C2776032975 @default.
- W2804367002 hasConceptScore W2804367002C2777348757 @default.
- W2804367002 hasConceptScore W2804367002C2777831001 @default.
- W2804367002 hasConceptScore W2804367002C2778186239 @default.
- W2804367002 hasConceptScore W2804367002C2779345533 @default.
- W2804367002 hasConceptScore W2804367002C2780117969 @default.
- W2804367002 hasConceptScore W2804367002C2780196419 @default.
- W2804367002 hasConceptScore W2804367002C519063684 @default.
- W2804367002 hasConceptScore W2804367002C522805319 @default.
- W2804367002 hasConceptScore W2804367002C529278444 @default.
- W2804367002 hasConceptScore W2804367002C71924100 @default.
- W2804367002 hasConceptScore W2804367002C86803240 @default.