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- W2804369969 abstract "Management of progressive multiple sclerosis (MS) is one of the main challenges of the new century. Based on our knowledge of pathophysiology, three therapeutic strategies are proposed: anti-inflammatory (ocrelizumab, siponimod…); remyelinating (opicinumab); and neuroprotective (high-dose biotin, ibudilast, simvastatin…). Nevertheless, despite recent promising positive clinical trials, new methodological approaches for therapeutic protocols with adaptable outcomes to assess progression are still needed." @default.
- W2804369969 created "2018-06-01" @default.
- W2804369969 creator A5035397915 @default.
- W2804369969 date "2018-06-01" @default.
- W2804369969 modified "2023-09-24" @default.
- W2804369969 title "Treatment of progressive multiple sclerosis: Challenges and promising perspectives" @default.
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- W2804369969 doi "https://doi.org/10.1016/j.neurol.2018.01.370" @default.
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