Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804392004> ?p ?o ?g. }
Showing items 1 to 89 of
89
with 100 items per page.
- W2804392004 endingPage "307" @default.
- W2804392004 startingPage "307" @default.
- W2804392004 abstract "Background/Aims: Quinolone hypersensitivity is rare, but most reactions are immediate onset characterized by the presence of urticaria, angioedema and anaphylaxis. The pathogenic mechanisms underlying immediate reactions are not defined clearly. We investigated the pathogenic mechanisms with detection of serum specific IgE to quinolone. Methods: We recruited 12 patients presenting immediate hypersensitivity reactions to olfoxacin and/or ciprofloxacin from Ajou University Hospital. Allergy skin test and oral challenge test were performed. Serum specific IgE antibody to ofloxacin-human serum albumin (HSA) conjugate was detected by ELISA, and ELISA inhibition tests were performed with additions of olfloxacin-HSA conjugate, free forms of ofloxain, ciprofloxacin and levofloxacin. Results: Eleven were females (91.7%) with a mean age of 39.6 years. The culprit drugs were ofloxacin in 5 patients (group I) and ciprofloxacin in 7 patients (group 2). Major symptoms were urticaria/angioedema in 7 patients and anaphylaxis in 5 patients. Serum specific IgE to ofloxacin-HSA conjugate was detected in 4(80%) of group 1, and 3(50%) of group 2 patients. Significant inhibitions were noted with additions of olfloxacin-HSA conjugate, free forms of olfloxacin, ciprofloxacin and levofloxacin which showed different patterns individually. Conclusions: We confirmed that IgE mediate response is a major pathogenic mechanism of quinolone hypersensitivity. Cross reactivity among the three quinolones were noted with individual difference." @default.
- W2804392004 created "2018-06-01" @default.
- W2804392004 creator A5007364197 @default.
- W2804392004 creator A5007597245 @default.
- W2804392004 creator A5038852974 @default.
- W2804392004 creator A5044524626 @default.
- W2804392004 creator A5064625853 @default.
- W2804392004 creator A5071337745 @default.
- W2804392004 creator A5085642896 @default.
- W2804392004 creator A5091474946 @default.
- W2804392004 date "2011-01-01" @default.
- W2804392004 modified "2023-09-23" @default.
- W2804392004 title "Immediate Hypersensitivity to Quinolone" @default.
- W2804392004 hasPublicationYear "2011" @default.
- W2804392004 type Work @default.
- W2804392004 sameAs 2804392004 @default.
- W2804392004 citedByCount "0" @default.
- W2804392004 crossrefType "journal-article" @default.
- W2804392004 hasAuthorship W2804392004A5007364197 @default.
- W2804392004 hasAuthorship W2804392004A5007597245 @default.
- W2804392004 hasAuthorship W2804392004A5038852974 @default.
- W2804392004 hasAuthorship W2804392004A5044524626 @default.
- W2804392004 hasAuthorship W2804392004A5064625853 @default.
- W2804392004 hasAuthorship W2804392004A5071337745 @default.
- W2804392004 hasAuthorship W2804392004A5085642896 @default.
- W2804392004 hasAuthorship W2804392004A5091474946 @default.
- W2804392004 hasConcept C141105273 @default.
- W2804392004 hasConcept C159654299 @default.
- W2804392004 hasConcept C16005928 @default.
- W2804392004 hasConcept C185592680 @default.
- W2804392004 hasConcept C203014093 @default.
- W2804392004 hasConcept C207480886 @default.
- W2804392004 hasConcept C2775933838 @default.
- W2804392004 hasConcept C2777995640 @default.
- W2804392004 hasConcept C2778049240 @default.
- W2804392004 hasConcept C2778512257 @default.
- W2804392004 hasConcept C2779922871 @default.
- W2804392004 hasConcept C2781276175 @default.
- W2804392004 hasConcept C501593827 @default.
- W2804392004 hasConcept C55493867 @default.
- W2804392004 hasConcept C71924100 @default.
- W2804392004 hasConcept C98274493 @default.
- W2804392004 hasConceptScore W2804392004C141105273 @default.
- W2804392004 hasConceptScore W2804392004C159654299 @default.
- W2804392004 hasConceptScore W2804392004C16005928 @default.
- W2804392004 hasConceptScore W2804392004C185592680 @default.
- W2804392004 hasConceptScore W2804392004C203014093 @default.
- W2804392004 hasConceptScore W2804392004C207480886 @default.
- W2804392004 hasConceptScore W2804392004C2775933838 @default.
- W2804392004 hasConceptScore W2804392004C2777995640 @default.
- W2804392004 hasConceptScore W2804392004C2778049240 @default.
- W2804392004 hasConceptScore W2804392004C2778512257 @default.
- W2804392004 hasConceptScore W2804392004C2779922871 @default.
- W2804392004 hasConceptScore W2804392004C2781276175 @default.
- W2804392004 hasConceptScore W2804392004C501593827 @default.
- W2804392004 hasConceptScore W2804392004C55493867 @default.
- W2804392004 hasConceptScore W2804392004C71924100 @default.
- W2804392004 hasConceptScore W2804392004C98274493 @default.
- W2804392004 hasIssue "1" @default.
- W2804392004 hasLocation W28043920041 @default.
- W2804392004 hasOpenAccess W2804392004 @default.
- W2804392004 hasPrimaryLocation W28043920041 @default.
- W2804392004 hasRelatedWork W1884074897 @default.
- W2804392004 hasRelatedWork W1963863000 @default.
- W2804392004 hasRelatedWork W1969737490 @default.
- W2804392004 hasRelatedWork W1970868532 @default.
- W2804392004 hasRelatedWork W1995460929 @default.
- W2804392004 hasRelatedWork W2006717800 @default.
- W2804392004 hasRelatedWork W2011712222 @default.
- W2804392004 hasRelatedWork W2015557878 @default.
- W2804392004 hasRelatedWork W2087162538 @default.
- W2804392004 hasRelatedWork W2090661205 @default.
- W2804392004 hasRelatedWork W2114567611 @default.
- W2804392004 hasRelatedWork W2116827255 @default.
- W2804392004 hasRelatedWork W2154662355 @default.
- W2804392004 hasRelatedWork W2168392100 @default.
- W2804392004 hasRelatedWork W2171330049 @default.
- W2804392004 hasRelatedWork W2328387909 @default.
- W2804392004 hasRelatedWork W2617782698 @default.
- W2804392004 hasRelatedWork W3101484955 @default.
- W2804392004 hasRelatedWork W3120249049 @default.
- W2804392004 hasRelatedWork W88019316 @default.
- W2804392004 hasVolume "2011" @default.
- W2804392004 isParatext "false" @default.
- W2804392004 isRetracted "false" @default.
- W2804392004 magId "2804392004" @default.
- W2804392004 workType "article" @default.