Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804433462> ?p ?o ?g. }
Showing items 1 to 78 of
78
with 100 items per page.
- W2804433462 endingPage "517" @default.
- W2804433462 startingPage "516" @default.
- W2804433462 abstract "The primary objective of islet transplantation—whereby islets are transplanted into the portal vein of patients with type 1 diabetes with problematic glycaemic control—is prevention of severe hypoglycaemia with substantially improved glycaemic control. 1 Shapiro AM Lakey JR Ryan EA et al. Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen. N Engl J Med. 2000; 343: 230-238 Crossref PubMed Scopus (4353) Google Scholar , 2 Barton FB Rickels MR Alejandro R et al. Improvement in outcomes of clinical islet transplantation: 1999–2010. Diabetes Care. 2012; 35: 1436-1445 Crossref PubMed Scopus (543) Google Scholar , 3 Hering BJ Clarke WR Bridges ND et al. Phase 3 trial of transplantation of human islets in type 1 diabetes complicated by severe hypoglycemia. Diabetes Care. 2016; 39: 1230-1240 Crossref PubMed Scopus (385) Google Scholar The TRIMECO study, reported in The Lancet Diabetes & Endocrinology by Sandrine Lablanche and colleagues, 4 Lablanche S Vantyghem M-C Kessler L et al. on behalf of the TRIMECO trial investigatorsIslet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trial. Lancet Diabetes Endocrinol. http://dx.doi.org/10.1016/S2213-8587(18)30078-0 Google Scholar is the first randomised study of islet transplantation, and is a landmark achievement by a major European trial group, providing robust evidence to guide clinical decision making in this field. Islet transplantation versus insulin therapy in patients with type 1 diabetes with severe hypoglycaemia or poorly controlled glycaemia after kidney transplantation (TRIMECO): a multicentre, randomised controlled trialFor the indications assessed in this study, islet transplantation effectively improves metabolic outcomes. Although studies with longer-term follow-up are needed, islet transplantation seems to be a valid option for patients with severe, unstable type 1 diabetes who are not responding to intensive medical treatments. However, immunosuppression can affect kidney function, necessitating careful selection of patients. Full-Text PDF" @default.
- W2804433462 created "2018-06-01" @default.
- W2804433462 creator A5017332392 @default.
- W2804433462 creator A5020943069 @default.
- W2804433462 creator A5032815945 @default.
- W2804433462 date "2018-07-01" @default.
- W2804433462 modified "2023-10-14" @default.
- W2804433462 title "Islet transplantation in type 1 diabetes: moving forward" @default.
- W2804433462 cites W1973424799 @default.
- W2804433462 cites W2040605985 @default.
- W2804433462 cites W2108979344 @default.
- W2804433462 cites W2133186034 @default.
- W2804433462 cites W2139152163 @default.
- W2804433462 cites W2155095400 @default.
- W2804433462 cites W2328786770 @default.
- W2804433462 cites W2341414956 @default.
- W2804433462 cites W2613641503 @default.
- W2804433462 doi "https://doi.org/10.1016/s2213-8587(18)30107-4" @default.
- W2804433462 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29776896" @default.
- W2804433462 hasPublicationYear "2018" @default.
- W2804433462 type Work @default.
- W2804433462 sameAs 2804433462 @default.
- W2804433462 citedByCount "12" @default.
- W2804433462 countsByYear W28044334622020 @default.
- W2804433462 countsByYear W28044334622021 @default.
- W2804433462 countsByYear W28044334622022 @default.
- W2804433462 crossrefType "journal-article" @default.
- W2804433462 hasAuthorship W2804433462A5017332392 @default.
- W2804433462 hasAuthorship W2804433462A5020943069 @default.
- W2804433462 hasAuthorship W2804433462A5032815945 @default.
- W2804433462 hasBestOaLocation W28044334622 @default.
- W2804433462 hasConcept C126322002 @default.
- W2804433462 hasConcept C134018914 @default.
- W2804433462 hasConcept C165220095 @default.
- W2804433462 hasConcept C177713679 @default.
- W2804433462 hasConcept C2777180221 @default.
- W2804433462 hasConcept C2777411314 @default.
- W2804433462 hasConcept C2780668416 @default.
- W2804433462 hasConcept C2781232474 @default.
- W2804433462 hasConcept C2911091166 @default.
- W2804433462 hasConcept C555293320 @default.
- W2804433462 hasConcept C71924100 @default.
- W2804433462 hasConceptScore W2804433462C126322002 @default.
- W2804433462 hasConceptScore W2804433462C134018914 @default.
- W2804433462 hasConceptScore W2804433462C165220095 @default.
- W2804433462 hasConceptScore W2804433462C177713679 @default.
- W2804433462 hasConceptScore W2804433462C2777180221 @default.
- W2804433462 hasConceptScore W2804433462C2777411314 @default.
- W2804433462 hasConceptScore W2804433462C2780668416 @default.
- W2804433462 hasConceptScore W2804433462C2781232474 @default.
- W2804433462 hasConceptScore W2804433462C2911091166 @default.
- W2804433462 hasConceptScore W2804433462C555293320 @default.
- W2804433462 hasConceptScore W2804433462C71924100 @default.
- W2804433462 hasIssue "7" @default.
- W2804433462 hasLocation W28044334621 @default.
- W2804433462 hasLocation W28044334622 @default.
- W2804433462 hasLocation W28044334623 @default.
- W2804433462 hasLocation W28044334624 @default.
- W2804433462 hasLocation W28044334625 @default.
- W2804433462 hasOpenAccess W2804433462 @default.
- W2804433462 hasPrimaryLocation W28044334621 @default.
- W2804433462 hasRelatedWork W2070806097 @default.
- W2804433462 hasRelatedWork W2076766966 @default.
- W2804433462 hasRelatedWork W2077843344 @default.
- W2804433462 hasRelatedWork W2106795497 @default.
- W2804433462 hasRelatedWork W2288478759 @default.
- W2804433462 hasRelatedWork W2315999720 @default.
- W2804433462 hasRelatedWork W2359343087 @default.
- W2804433462 hasRelatedWork W2372962057 @default.
- W2804433462 hasRelatedWork W2779313077 @default.
- W2804433462 hasRelatedWork W2966089421 @default.
- W2804433462 hasVolume "6" @default.
- W2804433462 isParatext "false" @default.
- W2804433462 isRetracted "false" @default.
- W2804433462 magId "2804433462" @default.
- W2804433462 workType "article" @default.