Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804502173> ?p ?o ?g. }
- W2804502173 endingPage "90" @default.
- W2804502173 startingPage "83" @default.
- W2804502173 abstract "The effectiveness of malaria screening and treatment highly depends on the low-cost access to the highly sensitive and specific malaria test. We report a real-time fluorescence nucleic acid testing device for malaria field detection with automated and scalable sample preparation capability. The device consists a compact analyzer and a disposable microfluidic reagent compact disc. The parasite DNA sample preparation and subsequent real-time LAMP detection were seamlessly integrated on a single microfluidic compact disc, driven by energy efficient non-centrifuge based magnetic field interactions. Each disc contains four parallel testing units which could be configured either as four identical tests or as four species-specific tests. When configured as species-specific tests, it could identify two of the most life-threatening malaria species (P. falciparum and P. vivax). The NAT device is capable of processing four samples simultaneously within 50 min turnaround time. It achieves a detection limit of ~0.5 parasites/µl for whole blood, sufficient for detecting asymptomatic parasite carriers. The combination of the sensitivity, specificity, cost, and scalable sample preparation suggests the real-time fluorescence LAMP device could be particularly useful for malaria screening in the field settings." @default.
- W2804502173 created "2018-06-01" @default.
- W2804502173 creator A5005484398 @default.
- W2804502173 creator A5006909259 @default.
- W2804502173 creator A5028385813 @default.
- W2804502173 creator A5044817441 @default.
- W2804502173 creator A5055361395 @default.
- W2804502173 date "2018-09-01" @default.
- W2804502173 modified "2023-10-15" @default.
- W2804502173 title "Sample-to-answer palm-sized nucleic acid testing device towards low-cost malaria mass screening" @default.
- W2804502173 cites W1535417777 @default.
- W2804502173 cites W1965344652 @default.
- W2804502173 cites W1969503178 @default.
- W2804502173 cites W1977784023 @default.
- W2804502173 cites W1981843126 @default.
- W2804502173 cites W1991420168 @default.
- W2804502173 cites W2009635288 @default.
- W2804502173 cites W2025345332 @default.
- W2804502173 cites W2040292376 @default.
- W2804502173 cites W2054241320 @default.
- W2804502173 cites W2063190485 @default.
- W2804502173 cites W2070739465 @default.
- W2804502173 cites W2075751712 @default.
- W2804502173 cites W2105275554 @default.
- W2804502173 cites W2108579383 @default.
- W2804502173 cites W2109482328 @default.
- W2804502173 cites W2110753623 @default.
- W2804502173 cites W2114502684 @default.
- W2804502173 cites W2115837962 @default.
- W2804502173 cites W2120827989 @default.
- W2804502173 cites W2121049991 @default.
- W2804502173 cites W2128554309 @default.
- W2804502173 cites W2144345536 @default.
- W2804502173 cites W2150293055 @default.
- W2804502173 cites W2152873423 @default.
- W2804502173 cites W2154837905 @default.
- W2804502173 cites W2161308091 @default.
- W2804502173 cites W2164575752 @default.
- W2804502173 cites W2179603580 @default.
- W2804502173 cites W2185854726 @default.
- W2804502173 cites W2254317378 @default.
- W2804502173 cites W2263670471 @default.
- W2804502173 cites W2267677500 @default.
- W2804502173 cites W2276635134 @default.
- W2804502173 cites W2305480684 @default.
- W2804502173 cites W2318848658 @default.
- W2804502173 cites W2333566082 @default.
- W2804502173 cites W2414929276 @default.
- W2804502173 cites W2510001807 @default.
- W2804502173 cites W2518653783 @default.
- W2804502173 cites W2530688039 @default.
- W2804502173 cites W2556952826 @default.
- W2804502173 cites W2561581586 @default.
- W2804502173 cites W2610512172 @default.
- W2804502173 cites W2761449473 @default.
- W2804502173 cites W2766991821 @default.
- W2804502173 cites W656955655 @default.
- W2804502173 doi "https://doi.org/10.1016/j.bios.2018.05.019" @default.
- W2804502173 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6459019" @default.
- W2804502173 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29803865" @default.
- W2804502173 hasPublicationYear "2018" @default.
- W2804502173 type Work @default.
- W2804502173 sameAs 2804502173 @default.
- W2804502173 citedByCount "40" @default.
- W2804502173 countsByYear W28045021732018 @default.
- W2804502173 countsByYear W28045021732019 @default.
- W2804502173 countsByYear W28045021732020 @default.
- W2804502173 countsByYear W28045021732021 @default.
- W2804502173 countsByYear W28045021732022 @default.
- W2804502173 countsByYear W28045021732023 @default.
- W2804502173 crossrefType "journal-article" @default.
- W2804502173 hasAuthorship W2804502173A5005484398 @default.
- W2804502173 hasAuthorship W2804502173A5006909259 @default.
- W2804502173 hasAuthorship W2804502173A5028385813 @default.
- W2804502173 hasAuthorship W2804502173A5044817441 @default.
- W2804502173 hasAuthorship W2804502173A5055361395 @default.
- W2804502173 hasBestOaLocation W28045021731 @default.
- W2804502173 hasConcept C111919701 @default.
- W2804502173 hasConcept C119128265 @default.
- W2804502173 hasConcept C142724271 @default.
- W2804502173 hasConcept C158007255 @default.
- W2804502173 hasConcept C171250308 @default.
- W2804502173 hasConcept C185592680 @default.
- W2804502173 hasConcept C192562407 @default.
- W2804502173 hasConcept C198531522 @default.
- W2804502173 hasConcept C203014093 @default.
- W2804502173 hasConcept C24107716 @default.
- W2804502173 hasConcept C2776841711 @default.
- W2804502173 hasConcept C2778048844 @default.
- W2804502173 hasConcept C2778371730 @default.
- W2804502173 hasConcept C2779134260 @default.
- W2804502173 hasConcept C2779997623 @default.
- W2804502173 hasConcept C2781369635 @default.
- W2804502173 hasConcept C2909011893 @default.
- W2804502173 hasConcept C3008058167 @default.
- W2804502173 hasConcept C41008148 @default.
- W2804502173 hasConcept C43617362 @default.
- W2804502173 hasConcept C48044578 @default.