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• W2804571594 abstract "Abstract With time, memories undergo a neural reorganization that is linked to a transformation of detailed, episodic into more semantic, gist-like memory. Traditionally, this reorganization is thought to involve a redistribution of memory from the hippocampus to neocortical areas. Here we report a time-dependent reorganization within the hippocampus, along its anterior–posterior axis, that is related to the transformation of detailed memories into gist-like representations. We show that mnemonic representations in the anterior hippocampus are highly distinct and that anterior hippocampal activity is associated with detailed memory but decreases over time. Posterior hippocampal representations, however, are more gist-like at a later retention interval, and do not decline over time. These findings indicate that, in addition to the well-known systems consolidation from hippocampus to neocortex, there are changes within the hippocampus that are crucial for the temporal dynamics of memory." @default.
• W2804571594 created "2018-06-01" @default.
• W2804571594 creator A5038927843 @default.
• W2804571594 creator A5056942614 @default.
• W2804571594 date "2018-03-23" @default.
• W2804571594 modified "2023-10-14" @default.
• W2804571594 title "Time-dependent memory transformation along the hippocampal anterior–posterior axis" @default.
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• W2804571594 doi "https://doi.org/10.1038/s41467-018-03661-7" @default.
• W2804571594 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5865114" @default.
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• W2804571594 hasPublicationYear "2018" @default.
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