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- W2804833713 abstract "With the introduction of thrombin and factor Xa inhibitors to the oral anticoagulant market, significant improvements in both efficacy and safety have been achieved. Early clinical and preclinical data suggest that inhibitors of factor XIa can provide a still safer alternative, with expanded efficacy for arterial indications. This Perspective provides an overview of target rationale and details of the discovery and development of inhibitors of factor XIa as next generation antithrombotic agents." @default.
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- W2804833713 date "2018-05-18" @default.
- W2804833713 modified "2023-09-25" @default.
- W2804833713 title "Factor XIa Inhibitors as New Anticoagulants" @default.
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- W2804833713 doi "https://doi.org/10.1021/acs.jmedchem.8b00173" @default.
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