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- W2804838523 abstract "Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disorder that always affects the respiratory muscles . It is characterized by degeneration of motor neurons in the brain and spinal cord. Respiratory complications are the most common causes of death in ALS and typically occur within 3 to 5 years of diagnosis. Because ALS affects both upper and lower motor neurons, it causes hyperreflexia , spasticity, muscle fasciculations , muscle atrophy , and weakness. It ultimately progresses to functional quadriplegia . ALS most commonly begins in the limbs, but in about one-third of cases it begins in the bulbar muscles responsible for speech and swallowing." @default.
- W2804838523 created "2018-06-01" @default.
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- W2804838523 date "2018-06-01" @default.
- W2804838523 modified "2023-10-02" @default.
- W2804838523 title "Amyotrophic Lateral Sclerosis and the Respiratory System" @default.
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- W2804838523 doi "https://doi.org/10.1016/j.ccm.2018.01.003" @default.
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