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- W2804852844 abstract "Background; Hepatitis C virus (HCV) infection is a public health problem worldwide. It is estimated more than 185 million people around the world have been infected with it according to the world health organization (WHO). The highest prevalence is in Egypt and constitute about 10-20% of the general population. Bleeding from esophago-gastric varices is the most important complication of cirrhosis. Fibro Scan is a non-invasive device that assesses stiffness of the liver via the technique of transient Elastography. Objective; to evaluate the role of fibro scan in prediction of esophageal varices in chronic HCV infected patients. Patients and methods; A cross sectional prospective study was conducted on 100 Egyptian patients with chronic HCV infection, Studied patients were subjected to full medical history, Routine laboratory investigations, Hepatitis markers including HBsAg, HCV antibody and HCV RNA by real time polymerase chain reaction (PCR), an Abdominal ultrasonography, upper gastrointestinal endoscopy and assessment of liver fibrosis by fibroscan which, was obtained using fibroscan device (Echosens, Paris, France) by an expert fibroscan operator who was not aware by patients data, abdominal ultrasound and upper gastrointestinal endoscopy results were done for all studied patients. Results: liver stiffness measurement revealed patients with values (2-33 kPa with mean ± SD of 8.40 ± 6.82) had no esophageal varices (EV) and patients with values of (11-68 kPa) had EV. And disturbed as the following; (11-54 kPa with mean ±SD of 26.071 ±15.606) for patients with grade I, (13-43 kPa with mean ±SD of 32.625 ±10.716) for patients with grade II, (32-64 kPa with mean ± SD of 43.188 ± 10.232) for patients with grade III and (22-68KPa with mean ±SD of 51.875 ±17.374) for patients with grade IV esophageal varices respectively (P 21 kPa have an accuracy of presence of EV." @default.
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- W2804852844 date "2018-01-01" @default.
- W2804852844 modified "2023-09-24" @default.
- W2804852844 title "Role of Liver Stiffness Measurement in Prediction of Esophageal Varices in Chronic Hepatitis C Virus Infected Egyptian Patients" @default.
- W2804852844 hasPublicationYear "2018" @default.
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