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- W2804871344 abstract "The increasing use of engineered organisms for industrial, clinical, and environmental applications poses a growing risk of spreading hazardous biological entities into the environment. To address this biosafety issue, significant effort has been invested in creating ways to confine these organisms and transgenic materials. Emerging technologies in synthetic biology involving genetic circuit engineering, genome editing, and gene expression regulation have led to the development of novel biocontainment systems. In this perspective, we highlight recent advances in biocontainment and suggest a number of approaches for future development, which may be applied to overcome remaining challenges in safeguard implementation." @default.
- W2804871344 created "2018-06-01" @default.
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- W2804871344 creator A5060277141 @default.
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- W2804871344 date "2018-05-16" @default.
- W2804871344 modified "2023-10-17" @default.
- W2804871344 title "Next-generation biocontainment systems for engineered organisms" @default.
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- W2804871344 doi "https://doi.org/10.1038/s41589-018-0056-x" @default.
- W2804871344 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29769737" @default.
- W2804871344 hasPublicationYear "2018" @default.
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