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- W2804909043 abstract "Pancreatic neuroendocrine tumors (PNETs) are a rare and heterogeneous group of neoplasia and differ in their clinical presentation, behavior, and prognosis based on both histological features and cancer stage at the time of diagnosis. Although small-sized tumors can be surgically resected, locally advanced and metastatic tumors confer a poor prognosis. In addition, only limited treatment options are available to the latter group of patients with PNETs, such as hormonal analogs, cytotoxic agents, and targeted therapy. In selected patients, liver-directed therapies are also used. As expected, clinicians taking care of these patients are challenged to develop an effective and comprehensive treatment strategy for their patients amid a wide variety of treatment modalities. Targeted therapy for PNETs is limited to sunitinib and everolimus. Presently, a number of clinical studies are ongoing to assess the efficacy of newer targeted agents alone and in combination with previous agents for the treatment of advanced PNETs. The authors reviewed the current treatment and also discussed the emerging agents and emphasized the need to identify biomarkers." @default.
- W2804909043 created "2018-06-01" @default.
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- W2804909043 date "2018-08-01" @default.
- W2804909043 modified "2023-09-27" @default.
- W2804909043 title "An update on the management of pancreatic neuroendocrine tumors" @default.
- W2804909043 cites W1565486843 @default.
- W2804909043 cites W1572368406 @default.
- W2804909043 cites W1575433014 @default.
- W2804909043 cites W1581678255 @default.
- W2804909043 cites W161352241 @default.
- W2804909043 cites W1839519286 @default.
- W2804909043 cites W1935825021 @default.
- W2804909043 cites W1968542980 @default.
- W2804909043 cites W1971118071 @default.
- W2804909043 cites W1971433696 @default.
- W2804909043 cites W1974766483 @default.
- W2804909043 cites W1977486980 @default.
- W2804909043 cites W1979644507 @default.
- W2804909043 cites W1980736766 @default.
- W2804909043 cites W1984619754 @default.
- W2804909043 cites W1984764077 @default.
- W2804909043 cites W1984882652 @default.
- W2804909043 cites W1987025782 @default.
- W2804909043 cites W1991718451 @default.
- W2804909043 cites W1992109464 @default.
- W2804909043 cites W1994118792 @default.
- W2804909043 cites W1999429171 @default.
- W2804909043 cites W1999626396 @default.
- W2804909043 cites W2000034871 @default.
- W2804909043 cites W2000318498 @default.
- W2804909043 cites W2002575907 @default.
- W2804909043 cites W2004535742 @default.
- W2804909043 cites W2005250386 @default.
- W2804909043 cites W2008997722 @default.
- W2804909043 cites W2017082986 @default.
- W2804909043 cites W2017283276 @default.
- W2804909043 cites W2017446931 @default.
- W2804909043 cites W2031048655 @default.
- W2804909043 cites W2031807907 @default.
- W2804909043 cites W2035214608 @default.
- W2804909043 cites W2035990123 @default.
- W2804909043 cites W2036812709 @default.
- W2804909043 cites W2042265119 @default.
- W2804909043 cites W2046522202 @default.
- W2804909043 cites W2051213610 @default.
- W2804909043 cites W2054656771 @default.
- W2804909043 cites W2058650437 @default.
- W2804909043 cites W2061269695 @default.
- W2804909043 cites W2061690773 @default.
- W2804909043 cites W2062056727 @default.
- W2804909043 cites W2062917093 @default.
- W2804909043 cites W2066167408 @default.
- W2804909043 cites W2068147173 @default.
- W2804909043 cites W2070750222 @default.
- W2804909043 cites W2071394735 @default.
- W2804909043 cites W2072519372 @default.
- W2804909043 cites W2073083832 @default.
- W2804909043 cites W2073639423 @default.
- W2804909043 cites W2077742161 @default.
- W2804909043 cites W2079432413 @default.
- W2804909043 cites W2079655663 @default.
- W2804909043 cites W2081019043 @default.
- W2804909043 cites W2081457024 @default.
- W2804909043 cites W2082472122 @default.
- W2804909043 cites W2082715008 @default.
- W2804909043 cites W2082980938 @default.
- W2804909043 cites W2082990839 @default.
- W2804909043 cites W2083853142 @default.
- W2804909043 cites W2085866999 @default.
- W2804909043 cites W2087378582 @default.
- W2804909043 cites W2089275510 @default.
- W2804909043 cites W2089548202 @default.
- W2804909043 cites W2090232354 @default.
- W2804909043 cites W2092194111 @default.
- W2804909043 cites W2095317693 @default.
- W2804909043 cites W2098482546 @default.
- W2804909043 cites W2099071304 @default.
- W2804909043 cites W2100030097 @default.
- W2804909043 cites W2100283328 @default.
- W2804909043 cites W2103453025 @default.
- W2804909043 cites W2106870507 @default.
- W2804909043 cites W2108721215 @default.
- W2804909043 cites W2109201048 @default.
- W2804909043 cites W2110922803 @default.
- W2804909043 cites W2115686439 @default.
- W2804909043 cites W2118672029 @default.
- W2804909043 cites W2119451851 @default.
- W2804909043 cites W2124584525 @default.
- W2804909043 cites W2126783165 @default.
- W2804909043 cites W2128267006 @default.
- W2804909043 cites W2128879260 @default.