Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804920656> ?p ?o ?g. }
Showing items 1 to 88 of
88
with 100 items per page.
- W2804920656 endingPage "951" @default.
- W2804920656 startingPage "943" @default.
- W2804920656 abstract "Abstract Background Epidermal hyperproliferation with abnormal differentiation, inflammation, and angiogenesis are the key features of psoriasis. Glucose transporter‐1 ( GLUT ‐1) is a member of facilitative sugar transporters that are integral membrane glycoproteins moving sugar across cell membrane. Objective The objective of this study was to study the GLUT ‐1 expression in psoriasis. Patients and methods Forty patients with psoriasis vulgaris and 20 healthy individuals were included in the study. Skin biopsies were taken from lesional and nonlesional skin of psoriasis patients as well as normal skin of control subjects. All were examined for GLUT ‐1 antibody expression by immunohistochemistry and GLUT ‐1 mRNA expression by real‐time polymerase chain reaction (RT‐PCR). In addition, specimens of psoriasis lesions were stained by hematoxylin and eosin and CD 31 for morphometric analysis of histopathological parameters. Results The intensity of GLUT ‐1 immunohistochemical expression and the relative levels of GLUT ‐1 mRNA expression in psoriasis lesions were upregulated in lesional skin of psoriasis patients in comparison with their nonlesional skin as well as normal control skin. GLUT ‐1 expression in psoriasis lesions showed significant positive correlations with Psoriasis Area and Severity Index ( PASI ) score, mean of epidermal thickness, inflammatory cell density, and microvessel density. Conclusion Glucose transporter‐1 could play a role not only in the onset of psoriasis but also in the progression and severity of the disease. It may participate in the pathogenesis of psoriasis through the facilitation of epidermal hyperproliferation, inflammation, and angiogenesis." @default.
- W2804920656 created "2018-06-01" @default.
- W2804920656 creator A5002208988 @default.
- W2804920656 creator A5027442647 @default.
- W2804920656 creator A5037278080 @default.
- W2804920656 creator A5061165006 @default.
- W2804920656 date "2018-05-24" @default.
- W2804920656 modified "2023-10-01" @default.
- W2804920656 title "Glucose transporter-1 (GLUT-1) expression in psoriasis: correlation with disease severity" @default.
- W2804920656 cites W1585687842 @default.
- W2804920656 cites W1992250154 @default.
- W2804920656 cites W1997410071 @default.
- W2804920656 cites W2000275347 @default.
- W2804920656 cites W2007169088 @default.
- W2804920656 cites W2008993758 @default.
- W2804920656 cites W2010189440 @default.
- W2804920656 cites W2013840510 @default.
- W2804920656 cites W2028656318 @default.
- W2804920656 cites W2045291897 @default.
- W2804920656 cites W2081175094 @default.
- W2804920656 cites W2095476606 @default.
- W2804920656 cites W2112331117 @default.
- W2804920656 cites W2117655424 @default.
- W2804920656 cites W2126592654 @default.
- W2804920656 cites W2160234571 @default.
- W2804920656 cites W2162873738 @default.
- W2804920656 cites W2753536197 @default.
- W2804920656 doi "https://doi.org/10.1111/ijd.14037" @default.
- W2804920656 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29797802" @default.
- W2804920656 hasPublicationYear "2018" @default.
- W2804920656 type Work @default.
- W2804920656 sameAs 2804920656 @default.
- W2804920656 citedByCount "17" @default.
- W2804920656 countsByYear W28049206562020 @default.
- W2804920656 countsByYear W28049206562021 @default.
- W2804920656 countsByYear W28049206562022 @default.
- W2804920656 countsByYear W28049206562023 @default.
- W2804920656 crossrefType "journal-article" @default.
- W2804920656 hasAuthorship W2804920656A5002208988 @default.
- W2804920656 hasAuthorship W2804920656A5027442647 @default.
- W2804920656 hasAuthorship W2804920656A5037278080 @default.
- W2804920656 hasAuthorship W2804920656A5061165006 @default.
- W2804920656 hasConcept C126322002 @default.
- W2804920656 hasConcept C142724271 @default.
- W2804920656 hasConcept C16005928 @default.
- W2804920656 hasConcept C161573976 @default.
- W2804920656 hasConcept C204232928 @default.
- W2804920656 hasConcept C2776914184 @default.
- W2804920656 hasConcept C2777011040 @default.
- W2804920656 hasConcept C2779306644 @default.
- W2804920656 hasConcept C2780394083 @default.
- W2804920656 hasConcept C2780564577 @default.
- W2804920656 hasConcept C2780942790 @default.
- W2804920656 hasConcept C71924100 @default.
- W2804920656 hasConceptScore W2804920656C126322002 @default.
- W2804920656 hasConceptScore W2804920656C142724271 @default.
- W2804920656 hasConceptScore W2804920656C16005928 @default.
- W2804920656 hasConceptScore W2804920656C161573976 @default.
- W2804920656 hasConceptScore W2804920656C204232928 @default.
- W2804920656 hasConceptScore W2804920656C2776914184 @default.
- W2804920656 hasConceptScore W2804920656C2777011040 @default.
- W2804920656 hasConceptScore W2804920656C2779306644 @default.
- W2804920656 hasConceptScore W2804920656C2780394083 @default.
- W2804920656 hasConceptScore W2804920656C2780564577 @default.
- W2804920656 hasConceptScore W2804920656C2780942790 @default.
- W2804920656 hasConceptScore W2804920656C71924100 @default.
- W2804920656 hasIssue "8" @default.
- W2804920656 hasLocation W28049206561 @default.
- W2804920656 hasLocation W28049206562 @default.
- W2804920656 hasOpenAccess W2804920656 @default.
- W2804920656 hasPrimaryLocation W28049206561 @default.
- W2804920656 hasRelatedWork W1562413899 @default.
- W2804920656 hasRelatedWork W1939356211 @default.
- W2804920656 hasRelatedWork W2141737447 @default.
- W2804920656 hasRelatedWork W2272121691 @default.
- W2804920656 hasRelatedWork W2590043955 @default.
- W2804920656 hasRelatedWork W2803532403 @default.
- W2804920656 hasRelatedWork W3031140446 @default.
- W2804920656 hasRelatedWork W3197871794 @default.
- W2804920656 hasRelatedWork W3213281834 @default.
- W2804920656 hasRelatedWork W4220764432 @default.
- W2804920656 hasVolume "57" @default.
- W2804920656 isParatext "false" @default.
- W2804920656 isRetracted "false" @default.
- W2804920656 magId "2804920656" @default.
- W2804920656 workType "article" @default.