Matches in SemOpenAlex for { <https://semopenalex.org/work/W2804920691> ?p ?o ?g. }
Showing items 1 to 77 of
77
with 100 items per page.
- W2804920691 abstract "Atherosclerosis is a chronic cardiovascular disease initiated by the accumulation of lipid-loaded macrophages within the artery wall. Chemokines can have several potential functions in atherosclerosis. CCL5, an inflammatory chemokine, is considered proatherogenic. Since CCL5 expression is dramatically increased in early mouse atherosclerotic lesions, the goals were to identify which cells express CCL5 and the functions of CCL5 in early lesion development. CCL5 mRNA and protein were up-regulated both by myeloid and endothelial cells in lesions. Bone marrow transplantation studies demonstrated that CCL5 deficiency in bone marrow-derived cells transiently affected lesion myeloid cell content but did not significantly affect macrophage proliferation or monocyte recruitment. Additionally, CCL5 deficiency in non-hematopoietic cells had no effect on lesion parameters. These studies suggest that although CCL5 is expressed abundantly within lesions, the effects of CCL5 deficiency in early lesion development is minimal and this may be due to compensatory functions of related chemokines.%%%%M.Sc." @default.
- W2804920691 created "2018-06-01" @default.
- W2804920691 creator A5003806625 @default.
- W2804920691 date "2017-11-01" @default.
- W2804920691 modified "2023-09-24" @default.
- W2804920691 title "The Expression and Function of CCL5 in Early Atherosclerosis" @default.
- W2804920691 hasPublicationYear "2017" @default.
- W2804920691 type Work @default.
- W2804920691 sameAs 2804920691 @default.
- W2804920691 citedByCount "0" @default.
- W2804920691 crossrefType "dissertation" @default.
- W2804920691 hasAuthorship W2804920691A5003806625 @default.
- W2804920691 hasConcept C101666144 @default.
- W2804920691 hasConcept C109159458 @default.
- W2804920691 hasConcept C116484652 @default.
- W2804920691 hasConcept C13373296 @default.
- W2804920691 hasConcept C142724271 @default.
- W2804920691 hasConcept C203014093 @default.
- W2804920691 hasConcept C2776090121 @default.
- W2804920691 hasConcept C2776914184 @default.
- W2804920691 hasConcept C2779282312 @default.
- W2804920691 hasConcept C2780007613 @default.
- W2804920691 hasConcept C2781156865 @default.
- W2804920691 hasConcept C2781184567 @default.
- W2804920691 hasConcept C28328180 @default.
- W2804920691 hasConcept C502942594 @default.
- W2804920691 hasConcept C71924100 @default.
- W2804920691 hasConcept C79484868 @default.
- W2804920691 hasConcept C86803240 @default.
- W2804920691 hasConcept C8891405 @default.
- W2804920691 hasConcept C95444343 @default.
- W2804920691 hasConceptScore W2804920691C101666144 @default.
- W2804920691 hasConceptScore W2804920691C109159458 @default.
- W2804920691 hasConceptScore W2804920691C116484652 @default.
- W2804920691 hasConceptScore W2804920691C13373296 @default.
- W2804920691 hasConceptScore W2804920691C142724271 @default.
- W2804920691 hasConceptScore W2804920691C203014093 @default.
- W2804920691 hasConceptScore W2804920691C2776090121 @default.
- W2804920691 hasConceptScore W2804920691C2776914184 @default.
- W2804920691 hasConceptScore W2804920691C2779282312 @default.
- W2804920691 hasConceptScore W2804920691C2780007613 @default.
- W2804920691 hasConceptScore W2804920691C2781156865 @default.
- W2804920691 hasConceptScore W2804920691C2781184567 @default.
- W2804920691 hasConceptScore W2804920691C28328180 @default.
- W2804920691 hasConceptScore W2804920691C502942594 @default.
- W2804920691 hasConceptScore W2804920691C71924100 @default.
- W2804920691 hasConceptScore W2804920691C79484868 @default.
- W2804920691 hasConceptScore W2804920691C86803240 @default.
- W2804920691 hasConceptScore W2804920691C8891405 @default.
- W2804920691 hasConceptScore W2804920691C95444343 @default.
- W2804920691 hasLocation W28049206911 @default.
- W2804920691 hasOpenAccess W2804920691 @default.
- W2804920691 hasPrimaryLocation W28049206911 @default.
- W2804920691 hasRelatedWork W1961573346 @default.
- W2804920691 hasRelatedWork W1990906756 @default.
- W2804920691 hasRelatedWork W2013378863 @default.
- W2804920691 hasRelatedWork W2021032684 @default.
- W2804920691 hasRelatedWork W2032598000 @default.
- W2804920691 hasRelatedWork W2042083424 @default.
- W2804920691 hasRelatedWork W2052511962 @default.
- W2804920691 hasRelatedWork W2153060970 @default.
- W2804920691 hasRelatedWork W2410338048 @default.
- W2804920691 hasRelatedWork W2755905165 @default.
- W2804920691 hasRelatedWork W2804291583 @default.
- W2804920691 hasRelatedWork W2887724599 @default.
- W2804920691 hasRelatedWork W2901423145 @default.
- W2804920691 hasRelatedWork W2946241219 @default.
- W2804920691 hasRelatedWork W2952826599 @default.
- W2804920691 hasRelatedWork W3000367192 @default.
- W2804920691 hasRelatedWork W3092601683 @default.
- W2804920691 hasRelatedWork W3130855283 @default.
- W2804920691 hasRelatedWork W3145067764 @default.
- W2804920691 hasRelatedWork W89396345 @default.
- W2804920691 isParatext "false" @default.
- W2804920691 isRetracted "false" @default.
- W2804920691 magId "2804920691" @default.
- W2804920691 workType "dissertation" @default.