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- W2804961907 abstract "L’hypercholestérolémie familiale est l’une des maladies héréditaires les plus fréquentes chez l’enfant, entraînant une élévation des taux de LDL (low-density lipoprotein) cholestérol dès la naissance. L’athérosclérose commence dès l’enfance et prédispose à la survenue prématurée d’accidents coronariens à l’âge adulte, c’est pourquoi le diagnostic et la prise en charge thérapeutique précoces sont essentiels. Cet article résume la démarche diagnostique devant une hypercholestérolémie familiale, les modalités et objectifs thérapeutiques et les indications du dépistage. Familial hypercholesterolemia is one of the most common inherited disorders in childhood that causes elevated serum levels of low-density lipoprotein (LDL) cholesterol from birth. Atherosclerosis begins in childhood and predisposes to premature coronary diseases in adulthood, underlining the need for early detection and therapeutic management. This article summarizes the diagnostic approach of familial hypercholesterolemia, the therapeutic modalities and goals, and the screening indications." @default.
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- W2804961907 date "2018-06-01" @default.
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- W2804961907 title "Hypercholestérolémie familiale : mise au point pratique" @default.
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- W2804961907 doi "https://doi.org/10.1016/j.perped.2018.04.012" @default.
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