FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2805120324> ?p ?o ?g. }

• W2805120324 endingPage "342" @default.
• W2805120324 startingPage "332" @default.
• W2805120324 abstract "In this study, we describe the development of a SFC-MS method for the quality control of cannabis plants that could be potentially adulterated with synthetic cannabinoids. Considering the high number of already available synthetic cannabinoids and the high rate of development of novel structures, we aimed to develop a generic method suitable for the analysis of a large panel of substances using seventeen synthetic cannabinoids from multiple classes as model compounds. Firstly, a suitable column was chosen after a screening phase. Secondly, optimal operating conditions were obtained following a robust optimization strategy based on a design of experiments and design space methodology (DoE-DS). Finally, the quantitative performances of the method were assessed with a validation according to the total error approach. The developed method has a run time of 9.4 min. It uses a simple modifier composition of methanol with 2% H2O and requires minimal sample preparation. It can chromatographically separate natural cannabinoids (except THC-A and CBD-A) from the synthetics assessed. Also, the use of mass spectrometry provides sensitivity and specificity. Moreover, this quality by design (QbD) approach permits the tuning of the method (within the DS) during routine analysis to achieve a desirable separation since the future compounds that should be analyzed could be unknown. The method was validated for the quantitation of a selected synthetic cannabinoid in fiber-type cannabis matrix over the range of 2.5% – 7.5% (w/w) with LOD value as low as 14.4 ng/mL. This generic method should be easy to implement in customs or QC laboratories in the context of counterfeit drugs tracking." @default.
• W2805120324 created "2018-06-13" @default.
• W2805120324 creator A5002218951 @default.
• W2805120324 creator A5006631727 @default.
• W2805120324 creator A5016997372 @default.
• W2805120324 creator A5038063185 @default.
• W2805120324 creator A5040689564 @default.
• W2805120324 creator A5045308475 @default.
• W2805120324 creator A5084302985 @default.
• W2805120324 creator A5091854000 @default.
• W2805120324 date "2018-08-01" @default.
• W2805120324 modified "2023-10-17" @default.
• W2805120324 title "Implementation of a generic SFC-MS method for the quality control of potentially counterfeited medicinal cannabis with synthetic cannabinoids" @default.
• W2805120324 cites W1922744550 @default.
• W2805120324 cites W1925414483 @default.
• W2805120324 cites W1960007621 @default.
• W2805120324 cites W1969997820 @default.
• W2805120324 cites W1988554722 @default.
• W2805120324 cites W1999914758 @default.
• W2805120324 cites W2010505430 @default.
• W2805120324 cites W2015340411 @default.
• W2805120324 cites W2020507678 @default.
• W2805120324 cites W2040813526 @default.
• W2805120324 cites W2047414434 @default.
• W2805120324 cites W2074114778 @default.
• W2805120324 cites W2075881972 @default.
• W2805120324 cites W2112949105 @default.
• W2805120324 cites W2120227293 @default.
• W2805120324 cites W2121480235 @default.
• W2805120324 cites W2164614248 @default.
• W2805120324 cites W2254148037 @default.
• W2805120324 cites W2282529829 @default.
• W2805120324 cites W2547054258 @default.
• W2805120324 cites W2551738542 @default.
• W2805120324 cites W2562656310 @default.
• W2805120324 cites W2620523760 @default.
• W2805120324 cites W2620956212 @default.
• W2805120324 cites W2740209163 @default.
• W2805120324 cites W2772251873 @default.
• W2805120324 cites W4230965759 @default.
• W2805120324 cites W43893483 @default.
• W2805120324 doi "https://doi.org/10.1016/j.jchromb.2018.05.049" @default.
• W2805120324 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29936369" @default.
• W2805120324 hasPublicationYear "2018" @default.
• W2805120324 type Work @default.
• W2805120324 sameAs 2805120324 @default.
• W2805120324 citedByCount "14" @default.
• W2805120324 countsByYear W28051203242019 @default.
• W2805120324 countsByYear W28051203242020 @default.
• W2805120324 countsByYear W28051203242021 @default.
• W2805120324 countsByYear W28051203242022 @default.
• W2805120324 countsByYear W28051203242023 @default.
• W2805120324 crossrefType "journal-article" @default.
• W2805120324 hasAuthorship W2805120324A5002218951 @default.
• W2805120324 hasAuthorship W2805120324A5006631727 @default.
• W2805120324 hasAuthorship W2805120324A5016997372 @default.
• W2805120324 hasAuthorship W2805120324A5038063185 @default.
• W2805120324 hasAuthorship W2805120324A5040689564 @default.
• W2805120324 hasAuthorship W2805120324A5045308475 @default.
• W2805120324 hasAuthorship W2805120324A5084302985 @default.
• W2805120324 hasAuthorship W2805120324A5091854000 @default.
• W2805120324 hasConcept C118552586 @default.
• W2805120324 hasConcept C127413603 @default.
• W2805120324 hasConcept C147789679 @default.
• W2805120324 hasConcept C15744967 @default.
• W2805120324 hasConcept C170493617 @default.
• W2805120324 hasConcept C183696295 @default.
• W2805120324 hasConcept C185592680 @default.
• W2805120324 hasConcept C187530423 @default.
• W2805120324 hasConcept C204320433 @default.
• W2805120324 hasConcept C2777056318 @default.
• W2805120324 hasConcept C2777846614 @default.
• W2805120324 hasConcept C2780871563 @default.
• W2805120324 hasConcept C43617362 @default.
• W2805120324 hasConcept C55493867 @default.
• W2805120324 hasConceptScore W2805120324C118552586 @default.
• W2805120324 hasConceptScore W2805120324C127413603 @default.
• W2805120324 hasConceptScore W2805120324C147789679 @default.
• W2805120324 hasConceptScore W2805120324C15744967 @default.
• W2805120324 hasConceptScore W2805120324C170493617 @default.
• W2805120324 hasConceptScore W2805120324C183696295 @default.
• W2805120324 hasConceptScore W2805120324C185592680 @default.
• W2805120324 hasConceptScore W2805120324C187530423 @default.
• W2805120324 hasConceptScore W2805120324C204320433 @default.
• W2805120324 hasConceptScore W2805120324C2777056318 @default.
• W2805120324 hasConceptScore W2805120324C2777846614 @default.
• W2805120324 hasConceptScore W2805120324C2780871563 @default.
• W2805120324 hasConceptScore W2805120324C43617362 @default.
• W2805120324 hasConceptScore W2805120324C55493867 @default.
• W2805120324 hasLocation W28051203241 @default.
• W2805120324 hasLocation W28051203242 @default.
• W2805120324 hasOpenAccess W2805120324 @default.
• W2805120324 hasPrimaryLocation W28051203241 @default.
• W2805120324 hasRelatedWork W2054470265 @default.
• W2805120324 hasRelatedWork W2190467875 @default.
• W2805120324 hasRelatedWork W2785669369 @default.
• W2805120324 hasRelatedWork W2886469289 @default.
• W2805120324 hasRelatedWork W2968849652 @default.

• next