FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2805189266> ?p ?o ?g. }

• W2805189266 abstract "During cataract surgery, maintaining an adequate degree of mydriasis throughout the entire operation is critical to allow for visualisation of the capsulorhexis and the crystalline lens. Good anaesthesia is also essential for safe intraocular surgery. Mydrane® is a new injectable intracameral solution containing two mydriatics (tropicamide 0.02% and phenylephrine 0.31%) and one anaesthetic (lidocaine 1%) that was developed as an alternative to the conventional topical pre-operative mydriatics used in cataract surgery. This study aimed to estimate the budget impact across a one year time frame using Mydrane® instead of topical dilating eye drops, for a UK hospital performing 3,000 cataract operations a year. A budget impact model (BIM) was developed to compare the economic outcomes associated with the use of Mydrane® versus topical drops (tropicamide 0.5% and phenylephrine 10%) in patients undergoing cataract surgery in a UK hospital. The outcomes of interest included costs and resource use (e.g. clinician time, mydriasis failures, operating room time, number of patients per vial of therapy etc.) associated with management of mydriasis in patients undergoing cataract surgery. All model inputs considered the UK hospital perspective without social or geographical variables. Deterministic sensitivity analyses were also performed to assess the model uncertainty. Introduction of Mydrane® is associated with a cost saving of £6,251 over 3,000 cataract surgeries in one year. The acquisition costs of the Mydrane® (£18,000 by year vs. £3,330 for eye drops) were balanced by substantial reductions in mainly nurses’ costs and time, plus a smaller contribution from savings in surgeons’ costs (£20,511) and lower costs associated with auxiliary dilation (£410 due to avoidance of additional dilation methods). Results of the sensitivity analyses confirmed the robustness of the model to the variation of inputs. Except for the duration of one session of eye drop instillation and the cost of Mydrane®, Mydrane® achieved an incremental cost gain compared to tropicamide/phenylephrine eye drops. Despite a higher acquisition cost of Mydrane®, the budget impact of Mydrane® on hospital budgets is neutral. Mydrane® offers a promising alternative to traditional regimes using eye drops, allowing for a better patient flow and optimisation of the surgery schedule with neutral budget impact." @default.
• W2805189266 created "2018-06-13" @default.
• W2805189266 creator A5021151483 @default.
• W2805189266 creator A5036045387 @default.
• W2805189266 creator A5051255323 @default.
• W2805189266 creator A5057830009 @default.
• W2805189266 creator A5077607579 @default.
• W2805189266 date "2018-04-19" @default.
• W2805189266 modified "2023-10-14" @default.
• W2805189266 title "Budget impact model of Mydrane®, a new intracameral injectable used for intra-operative mydriasis, from a UK hospital perspective" @default.
• W2805189266 cites W1981012150 @default.
• W2805189266 cites W2026393206 @default.
• W2805189266 cites W2033790078 @default.
• W2805189266 cites W2064247993 @default.
• W2805189266 cites W2090925471 @default.
• W2805189266 cites W2116699754 @default.
• W2805189266 cites W2126569826 @default.
• W2805189266 cites W2179049696 @default.
• W2805189266 cites W2237002671 @default.
• W2805189266 cites W4248644169 @default.
• W2805189266 cites W64056926 @default.
• W2805189266 doi "https://doi.org/10.1186/s12886-018-0746-x" @default.
• W2805189266 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5907706" @default.
• W2805189266 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29673317" @default.
• W2805189266 hasPublicationYear "2018" @default.
• W2805189266 type Work @default.
• W2805189266 sameAs 2805189266 @default.
• W2805189266 citedByCount "11" @default.
• W2805189266 countsByYear W28051892662020 @default.
• W2805189266 countsByYear W28051892662021 @default.
• W2805189266 countsByYear W28051892662022 @default.
• W2805189266 countsByYear W28051892662023 @default.
• W2805189266 crossrefType "journal-article" @default.
• W2805189266 hasAuthorship W2805189266A5021151483 @default.
• W2805189266 hasAuthorship W2805189266A5036045387 @default.
• W2805189266 hasAuthorship W2805189266A5051255323 @default.
• W2805189266 hasAuthorship W2805189266A5057830009 @default.
• W2805189266 hasAuthorship W2805189266A5077607579 @default.
• W2805189266 hasBestOaLocation W28051892661 @default.
• W2805189266 hasConcept C118487528 @default.
• W2805189266 hasConcept C119767625 @default.
• W2805189266 hasConcept C169760540 @default.
• W2805189266 hasConcept C2775888743 @default.
• W2805189266 hasConcept C2777394604 @default.
• W2805189266 hasConcept C2778257484 @default.
• W2805189266 hasConcept C2779109636 @default.
• W2805189266 hasConcept C2779567214 @default.
• W2805189266 hasConcept C2779996494 @default.
• W2805189266 hasConcept C2780054484 @default.
• W2805189266 hasConcept C2780472037 @default.
• W2805189266 hasConcept C2781104129 @default.
• W2805189266 hasConcept C2909138857 @default.
• W2805189266 hasConcept C42219234 @default.
• W2805189266 hasConcept C71924100 @default.
• W2805189266 hasConcept C86803240 @default.
• W2805189266 hasConceptScore W2805189266C118487528 @default.
• W2805189266 hasConceptScore W2805189266C119767625 @default.
• W2805189266 hasConceptScore W2805189266C169760540 @default.
• W2805189266 hasConceptScore W2805189266C2775888743 @default.
• W2805189266 hasConceptScore W2805189266C2777394604 @default.
• W2805189266 hasConceptScore W2805189266C2778257484 @default.
• W2805189266 hasConceptScore W2805189266C2779109636 @default.
• W2805189266 hasConceptScore W2805189266C2779567214 @default.
• W2805189266 hasConceptScore W2805189266C2779996494 @default.
• W2805189266 hasConceptScore W2805189266C2780054484 @default.
• W2805189266 hasConceptScore W2805189266C2780472037 @default.
• W2805189266 hasConceptScore W2805189266C2781104129 @default.
• W2805189266 hasConceptScore W2805189266C2909138857 @default.
• W2805189266 hasConceptScore W2805189266C42219234 @default.
• W2805189266 hasConceptScore W2805189266C71924100 @default.
• W2805189266 hasConceptScore W2805189266C86803240 @default.
• W2805189266 hasIssue "1" @default.
• W2805189266 hasLocation W28051892661 @default.
• W2805189266 hasLocation W28051892662 @default.
• W2805189266 hasLocation W28051892663 @default.
• W2805189266 hasLocation W28051892664 @default.
• W2805189266 hasLocation W28051892665 @default.
• W2805189266 hasOpenAccess W2805189266 @default.
• W2805189266 hasPrimaryLocation W28051892661 @default.
• W2805189266 hasRelatedWork W177125793 @default.
• W2805189266 hasRelatedWork W1994031997 @default.
• W2805189266 hasRelatedWork W1996748672 @default.
• W2805189266 hasRelatedWork W2083095773 @default.
• W2805189266 hasRelatedWork W2284040628 @default.
• W2805189266 hasRelatedWork W2345637665 @default.
• W2805189266 hasRelatedWork W2385661622 @default.
• W2805189266 hasRelatedWork W2396768777 @default.
• W2805189266 hasRelatedWork W2410820207 @default.
• W2805189266 hasRelatedWork W2519969609 @default.
• W2805189266 hasVolume "18" @default.
• W2805189266 isParatext "false" @default.
• W2805189266 isRetracted "false" @default.
• W2805189266 magId "2805189266" @default.
• W2805189266 workType "article" @default.