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W2805287130 abstract "Next-Generation Sequencing & Molecular Diagnostics Genome function, ChIP-Seq and personalized diagnosticsChandra S Pareek & Andrzej TretynChandra S PareekChandra Shekhar Pareek is Professor and Chair of Functional Genomics Laboratory and Group Leader of Translational Research Unit of Interdisciplinary Centre for Modern Technology, Nicolaus Copernicus University, Toruń, Poland. His research interests focus on development of immune-relevant gene markers, genome scan procedures and DNA pooling for mapping complex disease loci, massively parallel sequencing, integration of functional genomic towards genome-wide transcriptome analysis and interdisciplinary translational research in genomics.Search for more papers by this author & Andrzej TretynAndrzej Tretyn is Rector Magnificus (2012–2016) and Professor and Chair of Plant Physiology and Biotechnology of Nicolaus Copernicus University, Toruń, Poland. His research interests focus on cytophysiology, phytochrome, photomorphogenesis and calcium signaling in plants. His current research areas involve metagenomics, gene expression profiles in different digestive tract neoplasm, diagnostic test for breast cancer. He is a grantee of Wageningen Agricultural University (1988), Alexander von Humboldt Foundation (1989–1991) and Japanese Society for the Promotion of Science (2004).Search for more papers by this authorPublished Online:13 Feb 2013https://doi.org/10.2217/ebo.12.225AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInReddit View chapterAbstract: This chapter begins with a brief introduction of genome function as summarized in Figure 5.1, followed by an overview of recent developments and highlights on chromatin immunoprecipitation sequencing (ChIP-Seq) technology, particularly recent progresses in the development of computational tools for ChIP-Seq data analysis and its potential applications namely genome-wide identification of histone modifications locations, mapping of transcription factor (TF) binding sites, epigenetic profiling, motif discovery, nucleosome positioning, and prediction of TF regulatory networks. 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W2805287130 created "2018-06-13" @default.
W2805287130 creator A5052209564 @default.
W2805287130 creator A5080341246 @default.
W2805287130 date "2013-02-01" @default.
W2805287130 modified "2023-09-26" @default.
W2805287130 title "Genome function, ChIP-Seq and personalized diagnostics" @default.
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