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• W2805352022 startingPage "556" @default.
• W2805352022 abstract "Protease inhibitors significantly control physiologically relevant protease activities. Protease inhibitors from marine microbial sources are unique due to their rough living environmental conditions. In the present study, a protein protease inhibitor (PI) was produced from marine Oceanimonas sp. BPMS22. Seven different media were screened for the growth of the bacterium and production of PI. Different carbon and nitrogen sources were screened and optimized for the specific protease inhibitor activity. Three different growth models were checked for the best fit of the bacterial growth. A modified Gompertz model was selected as the best model for the growth of Oceanimonas sp. BPMS22 with the maximum specific growth rate of 0.165 hr−1 and doubling time of 4.2 hr. The production of PI takes place during the non-growing phase of the bacterial growth. A kinetic model for the production of PI during non-growing phase was used for studying various process parameters. From the model, the maximum trypsin inhibitor formation rate of 0.3802 IU per mg of biomass per hour was observed at 49.91 hr." @default.
• W2805352022 created "2018-06-13" @default.
• W2805352022 creator A5047028313 @default.
• W2805352022 creator A5076924211 @default.
• W2805352022 date "2018-06-05" @default.
• W2805352022 modified "2023-09-23" @default.
• W2805352022 title "Modeling of growth kinetics for an isolated marine bacterium,<i>Oceanimonas</i>sp. BPMS22 during the production of a trypsin inhibitor" @default.
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• W2805352022 doi "https://doi.org/10.1080/10826068.2018.1476878" @default.
• W2805352022 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29869945" @default.
• W2805352022 hasPublicationYear "2018" @default.
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