Matches in SemOpenAlex for { <https://semopenalex.org/work/W2805471073> ?p ?o ?g. }
- W2805471073 abstract "Abstract Many forms of lung disease manifest themselves as pathological changes in the transport of gas to the circulatory system, yet the difficulty of imaging this process remains a central obstacle to the comprehensive diagnosis of lung disorders. Using hyperpolarized xenon-129 as a surrogate marker for oxygen, we derived the temporal dynamics of gas transport from the ratio of two lung images obtained with different timing parameters. Additionally, by monitoring changes in the total hyperpolarized xenon signal intensity in the left side of the heart induced by depletion of xenon signal in the alveolar airspaces of interest, we quantified the contributions of selected lung volumes to the total pulmonary gas transport. In a rabbit model, we found that it takes at least 200 ms for xenon gas to enter the lung tissue and travel the distance from the airspaces to the heart. Additionally, our method shows that both lungs contribute fairly equally to the gas transport in healthy rabbits, but that this ratio changes in a rabbit model of acid aspiration. These results suggest that hyperpolarized xenon-129 MRI may improve our ability to measure pulmonary gas transport and detect associated pathological changes." @default.
- W2805471073 created "2018-06-13" @default.
- W2805471073 creator A5005347169 @default.
- W2805471073 creator A5006921976 @default.
- W2805471073 creator A5007352225 @default.
- W2805471073 creator A5010102754 @default.
- W2805471073 creator A5011126732 @default.
- W2805471073 creator A5013373381 @default.
- W2805471073 creator A5025285418 @default.
- W2805471073 creator A5039194767 @default.
- W2805471073 creator A5064485284 @default.
- W2805471073 creator A5090475597 @default.
- W2805471073 date "2018-05-09" @default.
- W2805471073 modified "2023-09-27" @default.
- W2805471073 title "Assessment of Pulmonary Gas Transport in Rabbits Using Hyperpolarized Xenon-129 Magnetic Resonance Imaging" @default.
- W2805471073 cites W1506716463 @default.
- W2805471073 cites W1571973433 @default.
- W2805471073 cites W1586431690 @default.
- W2805471073 cites W1849412223 @default.
- W2805471073 cites W1917018142 @default.
- W2805471073 cites W1942862135 @default.
- W2805471073 cites W1974102437 @default.
- W2805471073 cites W1989681775 @default.
- W2805471073 cites W1992193766 @default.
- W2805471073 cites W1993453452 @default.
- W2805471073 cites W2003307801 @default.
- W2805471073 cites W2003839103 @default.
- W2805471073 cites W2022452725 @default.
- W2805471073 cites W2031648991 @default.
- W2805471073 cites W2045169599 @default.
- W2805471073 cites W2045396817 @default.
- W2805471073 cites W2057733730 @default.
- W2805471073 cites W2076273965 @default.
- W2805471073 cites W2097925314 @default.
- W2805471073 cites W2099857251 @default.
- W2805471073 cites W2106263593 @default.
- W2805471073 cites W2111081037 @default.
- W2805471073 cites W2118995164 @default.
- W2805471073 cites W2119662418 @default.
- W2805471073 cites W2120811181 @default.
- W2805471073 cites W2128154647 @default.
- W2805471073 cites W2130923743 @default.
- W2805471073 cites W2148291045 @default.
- W2805471073 cites W2149707004 @default.
- W2805471073 cites W2154394773 @default.
- W2805471073 cites W2166880072 @default.
- W2805471073 cites W2252950939 @default.
- W2805471073 cites W2464921072 @default.
- W2805471073 cites W2506218417 @default.
- W2805471073 cites W2604112991 @default.
- W2805471073 cites W2616499496 @default.
- W2805471073 cites W2752942070 @default.
- W2805471073 cites W2775786529 @default.
- W2805471073 doi "https://doi.org/10.1038/s41598-018-25713-0" @default.
- W2805471073 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5943289" @default.
- W2805471073 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29743565" @default.
- W2805471073 hasPublicationYear "2018" @default.
- W2805471073 type Work @default.
- W2805471073 sameAs 2805471073 @default.
- W2805471073 citedByCount "9" @default.
- W2805471073 countsByYear W28054710732019 @default.
- W2805471073 countsByYear W28054710732020 @default.
- W2805471073 countsByYear W28054710732021 @default.
- W2805471073 countsByYear W28054710732022 @default.
- W2805471073 crossrefType "journal-article" @default.
- W2805471073 hasAuthorship W2805471073A5005347169 @default.
- W2805471073 hasAuthorship W2805471073A5006921976 @default.
- W2805471073 hasAuthorship W2805471073A5007352225 @default.
- W2805471073 hasAuthorship W2805471073A5010102754 @default.
- W2805471073 hasAuthorship W2805471073A5011126732 @default.
- W2805471073 hasAuthorship W2805471073A5013373381 @default.
- W2805471073 hasAuthorship W2805471073A5025285418 @default.
- W2805471073 hasAuthorship W2805471073A5039194767 @default.
- W2805471073 hasAuthorship W2805471073A5064485284 @default.
- W2805471073 hasAuthorship W2805471073A5090475597 @default.
- W2805471073 hasBestOaLocation W28054710731 @default.
- W2805471073 hasConcept C121332964 @default.
- W2805471073 hasConcept C126322002 @default.
- W2805471073 hasConcept C126838900 @default.
- W2805471073 hasConcept C142724271 @default.
- W2805471073 hasConcept C143409427 @default.
- W2805471073 hasConcept C178790620 @default.
- W2805471073 hasConcept C185592680 @default.
- W2805471073 hasConcept C2777714996 @default.
- W2805471073 hasConcept C2989005 @default.
- W2805471073 hasConcept C46141821 @default.
- W2805471073 hasConcept C548442186 @default.
- W2805471073 hasConcept C71924100 @default.
- W2805471073 hasConceptScore W2805471073C121332964 @default.
- W2805471073 hasConceptScore W2805471073C126322002 @default.
- W2805471073 hasConceptScore W2805471073C126838900 @default.
- W2805471073 hasConceptScore W2805471073C142724271 @default.
- W2805471073 hasConceptScore W2805471073C143409427 @default.
- W2805471073 hasConceptScore W2805471073C178790620 @default.
- W2805471073 hasConceptScore W2805471073C185592680 @default.
- W2805471073 hasConceptScore W2805471073C2777714996 @default.
- W2805471073 hasConceptScore W2805471073C2989005 @default.
- W2805471073 hasConceptScore W2805471073C46141821 @default.
- W2805471073 hasConceptScore W2805471073C548442186 @default.
- W2805471073 hasConceptScore W2805471073C71924100 @default.