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- W2805492197 abstract "Background: Otomycosis is a superficial fungal infection affecting the pinna and the external auditory canal, It is common worldwide but more prevalent in tropical and subtropical countries. Objectives: The aim of this study was to determine the etiologic agents causing otomycosis in our hospital as well as their susceptibility to the commonly used antifungal agents. Methodology : This was a hospital based descriptive study conducted on 122 patients attending the outpatient clinic of ear, nose and throat (ENT) department of Sohag university hospital and fulfilling our inclusion and exclusion criteria during April 2016 to April 2017 . Ear discharge specimens were collected on sterile cotton swabs for direct microscopic examination and inoculation on Sabouraud′s Dextrose Agar. Identification of yeast species was done by Vitek-2 automated system, in vitro antifungal susceptibility testing was done using disc diffusion method against the commonly used antifungal drugs. Results : In this study 102/122(83.61%) of the collected samples were positive for fungal infection. The most common fungal pathogens isolated from patients with otomycosis were Aspergillus and candida species, Aspergillus niger was the predominant fungal isolate (51%). Determination of in vitro antifungal susceptibility pattern showed that the mould isolates had the highest sensitivity to Voriconazole (93.48%) followed by Turbinafine (75%), while the highest resistance was to Fluconazole (100%) followed by Amphotericin B (41.3%). For the yeast isolates, the highest sensitivity was to Nystatine (88.24%) followed by Amphotericin B (82.35%), while the highest resistance was to Turbinafine (100%) followed by Itraconazole (94.12%)." @default.
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- W2805492197 date "2017-07-01" @default.
- W2805492197 modified "2023-09-27" @default.
- W2805492197 title "Identification and In Vitro Susceptibility Pattern of Fungal Infection Isolated from Patients with Otomycosis" @default.
- W2805492197 doi "https://doi.org/10.12816/0046288" @default.
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