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• W28055737 abstract "This chapter focuses on plasma exudate and its bioactive molecules. The chapter also reviews the airway exudation of leukocytes and in vivo mechanisms of epithelial damage and repair. Plasma exudation is one of the fundamental features of asthma and chronic obstructive pulmonary disease (COPD), especially during exacerbations. Exudation involves both plasma and cells, and plasma exudation indices correlate positively with bronchial responsiveness in asthma and negatively with FEV1 in patients with COPD. The airway lumen is the major destination for proteins and cells that are cleared from the airway mucosal tissue. Thus, airway plasma exudation is a first line innate immunity mechanism and is a specific sign of inflammatory mucosal processes in the respiratory tract. Inflammation does not occur without protein-exuding microvessels. During inflammatory plasma exudation events, all the circulating multipotent proteins appear, continuously or intermittently, in the important disease biophases. The exudative processes of the airways effectively eliminate proteins and cells from diseased mucosal tissue, and plasma exudation is regulated by and results in the deposition of bioactive molecules." @default.
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• W28055737 date "2002-01-01" @default.
• W28055737 modified "2023-10-16" @default.
• W28055737 title "Plasma Exudation" @default.
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• W28055737 doi "https://doi.org/10.1016/b978-012079028-9/50095-8" @default.
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