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• W2805581619 abstract "Background Human papillomaviruses ( HPV s) are strongly associated with the development of cervical carcinoma, and the distribution of HPV genotypes varies regionally. Methods To investigate the distribution characteristics of different genotypes of HPV infection in women in Wuhan, China, a total of 13 775 patients were enrolled over 2 years. Results Of these, 2436 patients were infected with HPV s, and the total infection rate was 17.68%. The infection rate of high‐risk HPV ( HR ‐ HPV ) was significantly higher (13.96%) than that of single low‐risk HPV ( LR ‐ HPV ; 3.72%). Among the HR ‐ HPV infections, the most common genotype was HPV 52 with an infection rate of 4.23%, followed by HPV s 16, 58, 39, and 51. The most common LR ‐ HPV genotype was HPV 81, followed by HPV s 6, 11, and 44. Patients under the age of 25 years were found to have the highest HPV infection rate ( P < .05). After the age range of 51‐55 years, a downward trend in total HPV s and HR ‐ HPV s was observed. The HPV infection rate for a single genotype was higher than that for multiple HPV s ( P < .01), and the detection rates in summer and winter were significantly higher than those in spring and autumn. Conclusions The results demonstrate that the distribution characteristics of various HPV genotype infections are associated with region and age and may be related to season. These data could be the basis for further epidemiological analysis into the control and prevention of HPV infection in this region." @default.
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• W2805581619 date "2018-06-03" @default.
• W2805581619 modified "2023-10-14" @default.
• W2805581619 title "Distribution characteristics of different human papillomavirus genotypes in women in Wuhan, China" @default.
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• W2805581619 doi "https://doi.org/10.1002/jcla.22581" @default.
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