Matches in SemOpenAlex for { <https://semopenalex.org/work/W2805812924> ?p ?o ?g. }
Showing items 1 to 82 of
82
with 100 items per page.
- W2805812924 endingPage "e250" @default.
- W2805812924 startingPage "e250" @default.
- W2805812924 abstract "Objective: To report the first case of pseudohyperaldosteronism due to mumijo consumption and provide the pathophysiologic background. Design and method: A 37-year-old woman on the 32nd-week of gestation was referred to our Department due to persistent hypokalemia, hypomagnesaemia and high blood pressure (BP). After meticulous investigation of her medical history, we found that the patient received without prescription mumijo over the last six-months. Physical examination was unremarkable. A thorough diagnostic work-up was then initiated to evaluate the persistent hypokalemia along with hypertension. Results: Serum potassium at admission was 2.7mmol/L, while serum magnesium was 1.72 mg/dl. The rest serum electrolytes values were within normal values. Office BP was 152/97mmHg. Air blood gases examination revealed the presence of metabolic alkalosis. Twenty-four-hour urine sample revealed high urinary excretion of potassium, magnesium and calcium. The 24 h ambulatory BP monitoring confirmed the increased BP levels (146/104mmHg) with non-dipping pattern. Consequently, patient had a high clinical suspicious for primary aldosteronism, thus underwent the diagnostic procedure of the disease. Interestingly, both plasma renin activity and aldosterone were found at remarkably low levels (0.08ng/ml, and > 0.16ng/100 ml, respectively). Normal early cortisol level (8.9mcg/100 ml) and 1 mg dexamethasone suppression test (2.3mcg/100 ml) excluded Cushing's syndrome. Moreover, dehydroepiandrosterone level measured in normal values (1.494,9ng/ml). These findings excluded the diagnosis of primary aldosteronism and emerged the probability of a pseudohyperaldosteronism-syndrome. Biochemical and hormonal normalization was observed with mumijo withdrawal. Conclusions: Our patient was finally diagnosed with pseudohyperaldosteronism-syndrome due to mumijo consumption, a ”licorice-like syndrome”, via inhibition of 11-hydroxysteroid dehydrogenase type 2, leading to impaired inactivation of cortisol to cortisone and finally to excessive mineralocorticoid activity, mainly in the distal- and cumulative-tubule. Clinicians should be aware of this side effect when prescribing mumijo, and a detailed medical history is always needed." @default.
- W2805812924 created "2018-06-13" @default.
- W2805812924 creator A5000659889 @default.
- W2805812924 creator A5012052161 @default.
- W2805812924 creator A5015945477 @default.
- W2805812924 creator A5026346426 @default.
- W2805812924 creator A5029015898 @default.
- W2805812924 creator A5037285876 @default.
- W2805812924 creator A5055456426 @default.
- W2805812924 creator A5068604858 @default.
- W2805812924 creator A5068639798 @default.
- W2805812924 creator A5077361613 @default.
- W2805812924 creator A5080219268 @default.
- W2805812924 creator A5085226634 @default.
- W2805812924 date "2018-06-01" @default.
- W2805812924 modified "2023-09-26" @default.
- W2805812924 title "A PREGNANT WOMAN WITH PSEUDOHYPERALDOSTERONISM DUE TO MUMIJO CONSUMPTION" @default.
- W2805812924 doi "https://doi.org/10.1097/01.hjh.0000539711.78560.e3" @default.
- W2805812924 hasPublicationYear "2018" @default.
- W2805812924 type Work @default.
- W2805812924 sameAs 2805812924 @default.
- W2805812924 citedByCount "0" @default.
- W2805812924 crossrefType "journal-article" @default.
- W2805812924 hasAuthorship W2805812924A5000659889 @default.
- W2805812924 hasAuthorship W2805812924A5012052161 @default.
- W2805812924 hasAuthorship W2805812924A5015945477 @default.
- W2805812924 hasAuthorship W2805812924A5026346426 @default.
- W2805812924 hasAuthorship W2805812924A5029015898 @default.
- W2805812924 hasAuthorship W2805812924A5037285876 @default.
- W2805812924 hasAuthorship W2805812924A5055456426 @default.
- W2805812924 hasAuthorship W2805812924A5068604858 @default.
- W2805812924 hasAuthorship W2805812924A5068639798 @default.
- W2805812924 hasAuthorship W2805812924A5077361613 @default.
- W2805812924 hasAuthorship W2805812924A5080219268 @default.
- W2805812924 hasAuthorship W2805812924A5085226634 @default.
- W2805812924 hasConcept C126322002 @default.
- W2805812924 hasConcept C134018914 @default.
- W2805812924 hasConcept C138976137 @default.
- W2805812924 hasConcept C198710026 @default.
- W2805812924 hasConcept C2776292634 @default.
- W2805812924 hasConcept C2776379505 @default.
- W2805812924 hasConcept C2778242168 @default.
- W2805812924 hasConcept C2778525890 @default.
- W2805812924 hasConcept C2780233176 @default.
- W2805812924 hasConcept C527108885 @default.
- W2805812924 hasConcept C71924100 @default.
- W2805812924 hasConcept C84393581 @default.
- W2805812924 hasConcept C90924648 @default.
- W2805812924 hasConceptScore W2805812924C126322002 @default.
- W2805812924 hasConceptScore W2805812924C134018914 @default.
- W2805812924 hasConceptScore W2805812924C138976137 @default.
- W2805812924 hasConceptScore W2805812924C198710026 @default.
- W2805812924 hasConceptScore W2805812924C2776292634 @default.
- W2805812924 hasConceptScore W2805812924C2776379505 @default.
- W2805812924 hasConceptScore W2805812924C2778242168 @default.
- W2805812924 hasConceptScore W2805812924C2778525890 @default.
- W2805812924 hasConceptScore W2805812924C2780233176 @default.
- W2805812924 hasConceptScore W2805812924C527108885 @default.
- W2805812924 hasConceptScore W2805812924C71924100 @default.
- W2805812924 hasConceptScore W2805812924C84393581 @default.
- W2805812924 hasConceptScore W2805812924C90924648 @default.
- W2805812924 hasIssue "Supplement 1" @default.
- W2805812924 hasLocation W28058129241 @default.
- W2805812924 hasOpenAccess W2805812924 @default.
- W2805812924 hasPrimaryLocation W28058129241 @default.
- W2805812924 hasRelatedWork W1993396385 @default.
- W2805812924 hasRelatedWork W1994557505 @default.
- W2805812924 hasRelatedWork W2032819459 @default.
- W2805812924 hasRelatedWork W2084069177 @default.
- W2805812924 hasRelatedWork W2098220178 @default.
- W2805812924 hasRelatedWork W2115973414 @default.
- W2805812924 hasRelatedWork W2176052578 @default.
- W2805812924 hasRelatedWork W2294623816 @default.
- W2805812924 hasRelatedWork W2380664026 @default.
- W2805812924 hasRelatedWork W63674808 @default.
- W2805812924 hasVolume "36" @default.
- W2805812924 isParatext "false" @default.
- W2805812924 isRetracted "false" @default.
- W2805812924 magId "2805812924" @default.
- W2805812924 workType "article" @default.