FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2805836144> ?p ?o ?g. }

• W2805836144 endingPage "e12930" @default.
• W2805836144 startingPage "e12930" @default.
• W2805836144 abstract "Data about the optimal management of immunosuppressive therapy in liver transplant (LT) recipients with bloodstream infection (BSI) are missing. We aimed to describe the management of immunosuppressive therapy at diagnosis of BSI in LT recipients and to assess its impact on 28-day mortality.We performed a single-center retrospective study of all LT recipients diagnosed with BSI, over 10-year period. Multivariate Cox regression analysis of risk factors for all cause 28-day mortality was adjusted for the propensity score of being managed with any reduction in immunosuppressive therapy at the diagnosis of BSI.We identified 209 episodes of BSI in 157 LT recipients: 107 (68%) male, median age 54 (IQR 48-63) years. Any reduction was made in 90 (43%) cases including: dosage reduction of ≥1 immunosuppressive drug in 31 (15%), discontinuation of ≥1 immunosuppressive drug in 28 (13%), both dosage reduction and discontinuation in 13 (6%), complete withdrawal of immunosuppressive therapy in 18 (9%) cases. All-cause 28-day mortality rate was 13.4%, varying from 22% to 7% (P = .002) in cases with and without any reduction. Cox regression showed septic shock (aHR 3.15, P = .007) and any reduction (aHR 2.50, P = .02) as independent risk factors for all-cause 28-day mortality, while Escherichia coli (aHR 0.38, P = .03) and source control (aHR 0.43, P = .04) were protective factors. The final model did not change after the introduction of the propensity score for any reduction.Any reduction in the immunosuppressive therapy was common and was associated with worse outcome in LT recipients developing BSI." @default.
• W2805836144 created "2018-06-13" @default.
• W2805836144 creator A5008060231 @default.
• W2805836144 creator A5010982417 @default.
• W2805836144 creator A5030411348 @default.
• W2805836144 creator A5032121417 @default.
• W2805836144 creator A5032788350 @default.
• W2805836144 creator A5034544385 @default.
• W2805836144 creator A5036277972 @default.
• W2805836144 creator A5039039137 @default.
• W2805836144 creator A5045135007 @default.
• W2805836144 creator A5061691353 @default.
• W2805836144 creator A5063758231 @default.
• W2805836144 creator A5085123624 @default.
• W2805836144 creator A5087457265 @default.
• W2805836144 creator A5088639153 @default.
• W2805836144 date "2018-06-13" @default.
• W2805836144 modified "2023-09-22" @default.
• W2805836144 title "Management of immunosuppressive therapy in liver transplant recipients who develop bloodstream infection" @default.
• W2805836144 cites W1491970318 @default.
• W2805836144 cites W1582717102 @default.
• W2805836144 cites W1761831931 @default.
• W2805836144 cites W1778713846 @default.
• W2805836144 cites W1991394425 @default.
• W2805836144 cites W1992908383 @default.
• W2805836144 cites W1998895073 @default.
• W2805836144 cites W2000445173 @default.
• W2805836144 cites W2001280008 @default.
• W2805836144 cites W2016877893 @default.
• W2805836144 cites W2036193982 @default.
• W2805836144 cites W2056396392 @default.
• W2805836144 cites W2061799973 @default.
• W2805836144 cites W2099690580 @default.
• W2805836144 cites W2115806935 @default.
• W2805836144 cites W2117561894 @default.
• W2805836144 cites W2135281485 @default.
• W2805836144 cites W2151673904 @default.
• W2805836144 cites W2158529768 @default.
• W2805836144 cites W2265329373 @default.
• W2805836144 cites W2280404143 @default.
• W2805836144 cites W2334617739 @default.
• W2805836144 cites W2404435360 @default.
• W2805836144 cites W2414409757 @default.
• W2805836144 cites W2548889063 @default.
• W2805836144 cites W2620123888 @default.
• W2805836144 doi "https://doi.org/10.1111/tid.12930" @default.
• W2805836144 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29809304" @default.
• W2805836144 hasPublicationYear "2018" @default.
• W2805836144 type Work @default.
• W2805836144 sameAs 2805836144 @default.
• W2805836144 citedByCount "10" @default.
• W2805836144 countsByYear W28058361442018 @default.
• W2805836144 countsByYear W28058361442019 @default.
• W2805836144 countsByYear W28058361442020 @default.
• W2805836144 countsByYear W28058361442021 @default.
• W2805836144 countsByYear W28058361442022 @default.
• W2805836144 countsByYear W28058361442023 @default.
• W2805836144 crossrefType "journal-article" @default.
• W2805836144 hasAuthorship W2805836144A5008060231 @default.
• W2805836144 hasAuthorship W2805836144A5010982417 @default.
• W2805836144 hasAuthorship W2805836144A5030411348 @default.
• W2805836144 hasAuthorship W2805836144A5032121417 @default.
• W2805836144 hasAuthorship W2805836144A5032788350 @default.
• W2805836144 hasAuthorship W2805836144A5034544385 @default.
• W2805836144 hasAuthorship W2805836144A5036277972 @default.
• W2805836144 hasAuthorship W2805836144A5039039137 @default.
• W2805836144 hasAuthorship W2805836144A5045135007 @default.
• W2805836144 hasAuthorship W2805836144A5061691353 @default.
• W2805836144 hasAuthorship W2805836144A5063758231 @default.
• W2805836144 hasAuthorship W2805836144A5085123624 @default.
• W2805836144 hasAuthorship W2805836144A5087457265 @default.
• W2805836144 hasAuthorship W2805836144A5088639153 @default.
• W2805836144 hasConcept C126322002 @default.
• W2805836144 hasConcept C167135981 @default.
• W2805836144 hasConcept C17923572 @default.
• W2805836144 hasConcept C179755657 @default.
• W2805836144 hasConcept C2777628635 @default.
• W2805836144 hasConcept C2778330430 @default.
• W2805836144 hasConcept C2778384902 @default.
• W2805836144 hasConcept C2778715236 @default.
• W2805836144 hasConcept C2780252810 @default.
• W2805836144 hasConcept C2911091166 @default.
• W2805836144 hasConcept C50382708 @default.
• W2805836144 hasConcept C71924100 @default.
• W2805836144 hasConcept C90924648 @default.
• W2805836144 hasConceptScore W2805836144C126322002 @default.
• W2805836144 hasConceptScore W2805836144C167135981 @default.
• W2805836144 hasConceptScore W2805836144C17923572 @default.
• W2805836144 hasConceptScore W2805836144C179755657 @default.
• W2805836144 hasConceptScore W2805836144C2777628635 @default.
• W2805836144 hasConceptScore W2805836144C2778330430 @default.
• W2805836144 hasConceptScore W2805836144C2778384902 @default.
• W2805836144 hasConceptScore W2805836144C2778715236 @default.
• W2805836144 hasConceptScore W2805836144C2780252810 @default.
• W2805836144 hasConceptScore W2805836144C2911091166 @default.
• W2805836144 hasConceptScore W2805836144C50382708 @default.
• W2805836144 hasConceptScore W2805836144C71924100 @default.
• W2805836144 hasConceptScore W2805836144C90924648 @default.

• next