Matches in SemOpenAlex for { <https://semopenalex.org/work/W2805874690> ?p ?o ?g. }
- W2805874690 endingPage "33" @default.
- W2805874690 startingPage "28" @default.
- W2805874690 abstract "Grape pomace extract (GPE) is a rich and relatively low-cost source of phenolic compounds. However, little is known about the main GPE metabolites in mammals, which could help explain the observed health-promoting effects. This study investigated the presence of parent compounds from flavanol, flavonol and stilbene families and their metabolites in rat plasma and tissues after an acute intake of GPE in doses of 300 and 600 mg kg/body weight. The measurement of free compounds and their metabolites was performed by ultra-high performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS). Results showed the presence of epicatechin, epicatechin methyl-glucuronide, epicatechin methyl-sulphate, catechin, catechin-glucuronide, quercetin methyl-glucuronide, resveratrol-3-glucuronide, resveratrol-4-glucuronide and resveratrol-3-sulphate in plasma, which was dose dependent. The most abundant measured compound in plasma was epicatechin-glucuronide. The presence of glucuronidated and methyl-glucuronidated forms of catechin were observed in the liver at both doses, while epicatechin-glucuronide and methyl-glucuronide were detected only upon intake of 600 mg GPE/kg body weight. At this dose epicatechin-glucuronide and methyl-glucuronide were also detected in muscle, and catechin methyl-glucuronide in adipose tissue. Results show the main GPE metabolites present in rat tissues after oral consumption, contributing to better understand the health benefits of GPE and its potential utilization as a functional ingredient." @default.
- W2805874690 created "2018-06-13" @default.
- W2805874690 creator A5002656360 @default.
- W2805874690 creator A5004709820 @default.
- W2805874690 creator A5006197121 @default.
- W2805874690 creator A5006609102 @default.
- W2805874690 creator A5048029995 @default.
- W2805874690 creator A5050805759 @default.
- W2805874690 date "2018-08-01" @default.
- W2805874690 modified "2023-10-14" @default.
- W2805874690 title "Phenolic metabolites in plasma and tissues of rats fed with a grape pomace extract as assessed by liquid chromatography-tandem mass spectrometry" @default.
- W2805874690 cites W1632977524 @default.
- W2805874690 cites W1832687689 @default.
- W2805874690 cites W1907955248 @default.
- W2805874690 cites W1914622032 @default.
- W2805874690 cites W1977463044 @default.
- W2805874690 cites W1987013638 @default.
- W2805874690 cites W1995830519 @default.
- W2805874690 cites W2004960233 @default.
- W2805874690 cites W2009429426 @default.
- W2805874690 cites W2011336591 @default.
- W2805874690 cites W2014069440 @default.
- W2805874690 cites W2014114876 @default.
- W2805874690 cites W2022283804 @default.
- W2805874690 cites W2023995851 @default.
- W2805874690 cites W2036573205 @default.
- W2805874690 cites W2039180104 @default.
- W2805874690 cites W2059315552 @default.
- W2805874690 cites W2061142443 @default.
- W2805874690 cites W2062477140 @default.
- W2805874690 cites W2067696344 @default.
- W2805874690 cites W2070100936 @default.
- W2805874690 cites W2076383234 @default.
- W2805874690 cites W2079862618 @default.
- W2805874690 cites W2080164215 @default.
- W2805874690 cites W2091640850 @default.
- W2805874690 cites W2093774322 @default.
- W2805874690 cites W2108687798 @default.
- W2805874690 cites W2112158545 @default.
- W2805874690 cites W2113287266 @default.
- W2805874690 cites W2118292221 @default.
- W2805874690 cites W2140714081 @default.
- W2805874690 cites W2142417450 @default.
- W2805874690 cites W2144573289 @default.
- W2805874690 cites W2151480882 @default.
- W2805874690 cites W2154580282 @default.
- W2805874690 cites W2157383251 @default.
- W2805874690 cites W2163388941 @default.
- W2805874690 cites W2170942205 @default.
- W2805874690 cites W2272622514 @default.
- W2805874690 cites W2324025901 @default.
- W2805874690 cites W2327088338 @default.
- W2805874690 cites W2328229204 @default.
- W2805874690 cites W2464063195 @default.
- W2805874690 cites W2499660737 @default.
- W2805874690 cites W2619677362 @default.
- W2805874690 cites W2622394281 @default.
- W2805874690 cites W2752638421 @default.
- W2805874690 cites W2793501527 @default.
- W2805874690 doi "https://doi.org/10.1016/j.abb.2018.05.021" @default.
- W2805874690 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29860029" @default.
- W2805874690 hasPublicationYear "2018" @default.
- W2805874690 type Work @default.
- W2805874690 sameAs 2805874690 @default.
- W2805874690 citedByCount "11" @default.
- W2805874690 countsByYear W28058746902018 @default.
- W2805874690 countsByYear W28058746902019 @default.
- W2805874690 countsByYear W28058746902020 @default.
- W2805874690 countsByYear W28058746902021 @default.
- W2805874690 countsByYear W28058746902022 @default.
- W2805874690 countsByYear W28058746902023 @default.
- W2805874690 crossrefType "journal-article" @default.
- W2805874690 hasAuthorship W2805874690A5002656360 @default.
- W2805874690 hasAuthorship W2805874690A5004709820 @default.
- W2805874690 hasAuthorship W2805874690A5006197121 @default.
- W2805874690 hasAuthorship W2805874690A5006609102 @default.
- W2805874690 hasAuthorship W2805874690A5048029995 @default.
- W2805874690 hasAuthorship W2805874690A5050805759 @default.
- W2805874690 hasConcept C162356407 @default.
- W2805874690 hasConcept C179998833 @default.
- W2805874690 hasConcept C185592680 @default.
- W2805874690 hasConcept C2776816829 @default.
- W2805874690 hasConcept C2777477808 @default.
- W2805874690 hasConcept C2778004101 @default.
- W2805874690 hasConcept C2779186261 @default.
- W2805874690 hasConcept C2779431889 @default.
- W2805874690 hasConcept C31827203 @default.
- W2805874690 hasConcept C43617362 @default.
- W2805874690 hasConcept C55493867 @default.
- W2805874690 hasConcept C64489805 @default.
- W2805874690 hasConcept C70899900 @default.
- W2805874690 hasConceptScore W2805874690C162356407 @default.
- W2805874690 hasConceptScore W2805874690C179998833 @default.
- W2805874690 hasConceptScore W2805874690C185592680 @default.
- W2805874690 hasConceptScore W2805874690C2776816829 @default.
- W2805874690 hasConceptScore W2805874690C2777477808 @default.
- W2805874690 hasConceptScore W2805874690C2778004101 @default.
- W2805874690 hasConceptScore W2805874690C2779186261 @default.