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• W2806016413 abstract "Exposure to brief periods of circulatory occlusion and reperfusion before an exercise (i.e. ischemic preconditioning - IPC) has been suggested to decrease exercise-induced fatigability, but placebo effects are yet to be fully determined. It is also not known if IPC can alter perceived pain and effort during isometric contractions performed with the lower extremity muscles. PURPOSE: To determine if IPC can decrease fatigability, perceived effort and pain of the lower extremity muscles during isometric contractions. METHODS: 12 individuals (27± 4 years) were submitted to cycles of ischemia and reperfusion by inflating a cuff to the non-dominant leg and arm in 3 separate and randomized sessions: A) IPC that consisted of 3 cycles of ischemia and reperfusion of 5 minutes each; B) SHAM session where cuffs were inflated for only 1 minute (not sufficient to induce ischemia), but reperfusion and total times of intervention were similar to those of the IPC session; C) Control session with no cuffs involved. Placebo induction was performed by saying that both IPC and SHAM would improve performance compared to control. Nocebo avoidance was accomplished by telling individuals that IPC would be harmless despite circulatory occlusion sensations. In each session, isometric contraction of the plantar flexor muscle was performed at 20% of maximal voluntary contraction (MVC), with the dominant leg, until task failure. Pain and ratings of perceived exertion were assessed during contractions with a Visual Analogue Scale (0-10). RESULTS: Time to task failure was greater in the IPC compared with SHAM and control sessions (25.1 ± 4 vs. 19.2 ± 2 vs. 20.3 ± 3 min respectively, session effect: P = 0.04). MVC at task failure was 60 ± 2 % lower than baseline (time effect: P < 0.001) for all test sessions (session × time: P = 0.31). At 25 % of time to task failure, exercise-induced pain was lower in IPC compared with SHAM and control sessions (1.3 ± 1 vs. 1.9 ± 1 vs. 2.6 ± 2 respectively, P = 0.03). Ratings of perceived exertion were similar between test sessions (session effect and session × time: P > 0.05). CONCLUSIONS: Compared with the control session, IPC increased time to task failure and decreased exercise-induced pain during fatiguing contraction of the plantar flexor muscles. Placebo effects induced in the SHAM session had minimal effects in these variables." @default.
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• W2806016413 date "2018-05-01" @default.
• W2806016413 modified "2023-10-01" @default.
• W2806016413 title "Fatigability of Plantar Flexor Muscles After Remote Ischemic Preconditioning" @default.
• W2806016413 doi "https://doi.org/10.1249/01.mss.0000536530.07117.fa" @default.
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