FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2806084205> ?p ?o ?g. }

• W2806084205 abstract "The well-known nosocomial pathogen Clostridium difficile has recently been recognized as a community-associated pathogen. As livestock animals carry and shed C. difficile in their feces, animal manure-based composts may play an important role in disseminating toxigenic C. difficile strains into the agricultural environment. The present study surveyed C. difficile contamination of commercially available composts and animal manure. Presumptive C. difficile isolates were confirmed by testing for the tpi housekeeping gene in addition to Gram staining. The confirmed C. difficile isolates were further tested for toxigenicity, PCR ribotype, and susceptibilities to selected antibiotics. C. difficile was found in 51 out of 142 samples (36%). A total of 58 C. difficile strains were isolated from those 51 positive compost/manure samples. The presence of C. difficile in compost did not significantly correlate (P > 0.05) with the physical and most microbiological parameters, including the presence of fecal coliforms. The majority of C. difficile isolates were toxigenic, with 63.8% positive for the toxin A gene (tcdA) and 67.2% positive for the toxin B gene (tcdB). Only 3 isolates (5.17%) were positive for the binary toxins. There were 38 different PCR ribotypes among the 58 C. difficile isolates, and ribotype 106 was the most prevalent, followed by ribotypes 020 and 412. All C. difficile isolates were susceptible to the selected antibiotics, but >50% of the isolates had reduced susceptibility to clindamycin by the agar dilution method. This study indicates that compost may be a reservoir of toxigenic C. difficile strains.IMPORTANCEClostridium difficile infection (CDI) is a leading cause of antibiotic-associated diarrhea in health care facilities in developed countries. Extended hospital stays and recurrences severely increase the cost of treatments and the high mortality rate that is observed among the elderly. Community-associated CDI cases that occur without any recent contact with the hospital environment are increasing. Studies have reported the isolation of virulent C. difficile strains from water, soil, meat, vegetables, pets, livestock animals, and animal manure. The objective of this study was to isolate and characterize C. difficile strains from animal manure and commercially available compost products. Our results demonstrate that not only unprocessed animal manure but also finished composts made of different feedstocks can serve as a reservoir for C. difficile as well. Most importantly, our study revealed that properly processed compost is a potential source of toxigenic and clindamycin-resistant C. difficile isolates." @default.
• W2806084205 created "2018-06-13" @default.
• W2806084205 creator A5058405099 @default.
• W2806084205 creator A5064069109 @default.
• W2806084205 date "2018-08-15" @default.
• W2806084205 modified "2023-10-10" @default.
• W2806084205 title "Isolation of Toxigenic Clostridium difficile from Animal Manure and Composts Being Used as Biological Soil Amendments" @default.
• W2806084205 cites W1512830638 @default.
• W2806084205 cites W1969082150 @default.
• W2806084205 cites W1973641407 @default.
• W2806084205 cites W1979973356 @default.
• W2806084205 cites W1986683907 @default.
• W2806084205 cites W1987862078 @default.
• W2806084205 cites W1990450579 @default.
• W2806084205 cites W1994041886 @default.
• W2806084205 cites W1995263808 @default.
• W2806084205 cites W1998499711 @default.
• W2806084205 cites W2026323870 @default.
• W2806084205 cites W2027932082 @default.
• W2806084205 cites W2037610927 @default.
• W2806084205 cites W2049067874 @default.
• W2806084205 cites W2074767784 @default.
• W2806084205 cites W2077265045 @default.
• W2806084205 cites W2077695558 @default.
• W2806084205 cites W2095709513 @default.
• W2806084205 cites W2100085137 @default.
• W2806084205 cites W2102391355 @default.
• W2806084205 cites W2104302404 @default.
• W2806084205 cites W2108657897 @default.
• W2806084205 cites W2113851350 @default.
• W2806084205 cites W2125061699 @default.
• W2806084205 cites W2131719434 @default.
• W2806084205 cites W2132112261 @default.
• W2806084205 cites W2132647114 @default.
• W2806084205 cites W2155780941 @default.
• W2806084205 cites W2159769705 @default.
• W2806084205 cites W2190866798 @default.
• W2806084205 cites W2299457138 @default.
• W2806084205 cites W2342087544 @default.
• W2806084205 cites W2554662037 @default.
• W2806084205 cites W2585403260 @default.
• W2806084205 cites W2791485400 @default.
• W2806084205 doi "https://doi.org/10.1128/aem.00738-18" @default.
• W2806084205 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6070769" @default.
• W2806084205 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29858208" @default.
• W2806084205 hasPublicationYear "2018" @default.
• W2806084205 type Work @default.
• W2806084205 sameAs 2806084205 @default.
• W2806084205 citedByCount "30" @default.
• W2806084205 countsByYear W28060842052019 @default.
• W2806084205 countsByYear W28060842052020 @default.
• W2806084205 countsByYear W28060842052021 @default.
• W2806084205 countsByYear W28060842052022 @default.
• W2806084205 countsByYear W28060842052023 @default.
• W2806084205 crossrefType "journal-article" @default.
• W2806084205 hasAuthorship W2806084205A5058405099 @default.
• W2806084205 hasAuthorship W2806084205A5064069109 @default.
• W2806084205 hasBestOaLocation W28060842051 @default.
• W2806084205 hasConcept C2777458120 @default.
• W2806084205 hasConcept C2780739461 @default.
• W2806084205 hasConcept C2994496256 @default.
• W2806084205 hasConcept C38304854 @default.
• W2806084205 hasConcept C42972112 @default.
• W2806084205 hasConcept C501593827 @default.
• W2806084205 hasConcept C61716771 @default.
• W2806084205 hasConcept C6557445 @default.
• W2806084205 hasConcept C71924100 @default.
• W2806084205 hasConcept C86803240 @default.
• W2806084205 hasConcept C89423630 @default.
• W2806084205 hasConcept C97505648 @default.
• W2806084205 hasConceptScore W2806084205C2777458120 @default.
• W2806084205 hasConceptScore W2806084205C2780739461 @default.
• W2806084205 hasConceptScore W2806084205C2994496256 @default.
• W2806084205 hasConceptScore W2806084205C38304854 @default.
• W2806084205 hasConceptScore W2806084205C42972112 @default.
• W2806084205 hasConceptScore W2806084205C501593827 @default.
• W2806084205 hasConceptScore W2806084205C61716771 @default.
• W2806084205 hasConceptScore W2806084205C6557445 @default.
• W2806084205 hasConceptScore W2806084205C71924100 @default.
• W2806084205 hasConceptScore W2806084205C86803240 @default.
• W2806084205 hasConceptScore W2806084205C89423630 @default.
• W2806084205 hasConceptScore W2806084205C97505648 @default.
• W2806084205 hasIssue "16" @default.
• W2806084205 hasLocation W28060842051 @default.
• W2806084205 hasLocation W28060842052 @default.
• W2806084205 hasLocation W28060842053 @default.
• W2806084205 hasLocation W28060842054 @default.
• W2806084205 hasOpenAccess W2806084205 @default.
• W2806084205 hasPrimaryLocation W28060842051 @default.
• W2806084205 hasRelatedWork W2042780382 @default.
• W2806084205 hasRelatedWork W2106583741 @default.
• W2806084205 hasRelatedWork W2132207617 @default.
• W2806084205 hasRelatedWork W2154900496 @default.
• W2806084205 hasRelatedWork W2554662037 @default.
• W2806084205 hasRelatedWork W2801332876 @default.
• W2806084205 hasRelatedWork W2806084205 @default.
• W2806084205 hasRelatedWork W2892186521 @default.
• W2806084205 hasRelatedWork W2968050891 @default.
• W2806084205 hasRelatedWork W3194354818 @default.
• W2806084205 hasVolume "84" @default.

• next