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• W2806191520 abstract "We construct a pathwise formulation for a multitype age-structured population dynamics, which involves an age-dependent cell replication and transition of gene- or phenotypes. By employing the formulation, we derive a variational representation of the stationary population growth rate; the representation comprises a tradeoff relation between growth effects and a single-cell intrinsic dynamics described by a semi-Markov process. This variational representation leads to a response relation of the stationary population growth rate, in which statistics on a retrospective history work as the response coefficients. These results contribute to predicting and controlling growing populations based on experimentally observed cell-lineage information." @default.
• W2806191520 created "2018-06-13" @default.
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• W2806191520 date "2019-01-11" @default.
• W2806191520 modified "2023-09-30" @default.
• W2806191520 title "Fitness response relation of a multitype age-structured population dynamics" @default.
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• W2806191520 doi "https://doi.org/10.1103/physreve.99.012413" @default.
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