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• W2806227527 abstract "Advances in the Management of Inflammatory Bowel Disease Clinical features and diagnosis of Crohn’s diseaseEpameinondas V Tsianos, Konstantinos H Katsanos & Vasileios E TsianosEpameinondas V TsianosEpameinondas V Tsianos is Professor of Internal Medicine at the Medical School, University of Ioannina, Greece. He is a member of the Greek Society of Gastroenterology, American Society of Gastroenterology and other medical societies. He is a member of the editorial board of the World Journal of Gastroenterology, European Journal of Internal Medicine and Annals of Gastroenterology. He has authored more than 650 abstracts in international journals and congresses and more than 253 Greek and 281 international original papers. Many abstracts have received distinctions and he was elected Professor of Gastroenterology since 1996 and Professor of Internal Medicine since 2001 at the Medical School of Ioannina, Greece.Search for more papers by this author, Konstantinos H KatsanosKonstantinos H Katsanos is Lecturer in Gastroenterology in the First Department of Internal Medicine and Hepato-Gastroenterology Unit at the University Hospital and the Medical School of Ioannina, Greece. He is a fellow of the European Board of Gastroenterology, member of the European Crohn’s and Colitis Organization, board member of the Greek IBD Study Group and Associate Editor of Annals of Gastroenterology. His research interests are IBD epidemiology, clinical trials, pharmacogenetics and immunology.Search for more papers by this author & Vasileios E TsianosVasileios E Tsianos is a PhD student at the Medical School, University of Ioannina. His thesis title is Study of the genetic polymorphism of IBD in NW Greece. He is also an undergraduate student at the Medical School, University of Ioannina. Since late 2009, he has collaborated with the Research Laboratory of Immunology, University of Ioannina and is responsible for the laboratory part of the Gastro-Intestinal BioBank. His major research interests include chronic diseases of the digestive system, human genetics and immunology.Search for more papers by this authorPublished Online:13 Mar 2013https://doi.org/10.2217/ebo.13.118AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInReddit View chapterAbstract: Crohn’s disease (CD) most frequently presents in late adolescence or early adulthood and seems to be equally distributed between the sexes. CD may involve any part of the gastrointestinal tract from the mouth to the anus and symptoms at presentation vary depending on the location, behavior and severity of disease, as well as extraintestinal manifestations. Historical surveys have revealed descriptions of apparent cases of CD as far as back as Morgani in 1769. In 1813, Coombe reported the clinical history and autopsy finding of a young man with presumable obstructing CD. In 1828, Abercrombie described a similar case and Moore and Fenwick reported similar cases. A landmark paper was published in 1913 by Dalziel describing nine cases undergoing surgery for a ‘distal ileum’ inflammatory disease. In 1933, Crohn presented his paper with Oppenheimer and Ginzburg to the American Medical Association. They referred to a disease, which they called ‘terminal ileitis’. During the discussion, Bargen from the Mayo Clinic suggested the term ‘regional ileitis’. The classic paper was then first published in the Journal of the American Medical Association in 1932. The aim of the physician when managing a patient with probable CD is to establish the diagnosis and distribution of disease by appropriate methods and techniques, because this influences the choice of treatment and the short- and long-term patient outcome. References1 Van Assche G , Dignass A , Panes J et al. The second European evidence-based Consensus on the diagnosis and management of Crohn’s disease: definitions and diagnosis . J. Crohns Colitis 4 (1) , 7 – 27 (2010) . Crossref, Medline, Google Scholar2 Travis S , Van Assche G , Dignass A . On the second ECCO consensus on Crohn’s disease . J. Crohns Colitis 4 (1) , 1 – 6 (2010) . Crossref, Medline, Google Scholar3 Baumgart DC . The diagnosis and treatment of Crohn’s disease and ulcerative colitis . Dtsch Arztebl Int 106 (8) , 123 – 133 (2009) . Medline, Google Scholar4 Tsianos EV , Katsanos KH , Tsianos VE . The role of genetics in the diagnosis and prognosis of Crohn’s disease . World J. 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Crossref, Medline, Google Scholar18 Rimola J , Rodriguez S , Garcia-Bosch O et al. Magnetic resonance for assessment of disease activity and severity in ileocolonic Crohn’s disease . Gut 58 (8) , 113 – 120 (2009) . Google Scholar19 Hyams J , Markowitz J , Otley A et al. Evaluation of the pediatric Crohn disease activity index: a prospective multicenter experience . J. Pediatr. Gastroenterol. Nutr. 41 (4) , 416 – 421 (2005) . Crossref, Medline, Google Scholar20 Rutgeerts P , Geboes K , Vantrappen G et al. Predictability of the postoperative course of Crohn’s disease . Gastroenterology 99 (4) , 956 – 963 (1990) . Crossref, Medline, CAS, Google ScholarFiguresReferencesRelatedDetails Advances in the Management of Inflammatory Bowel DiseaseMetrics Downloaded 15 times History Published online 13 March 2013 Published in print March 2013 Information© Future Medicine Ltd© Future Medicine LtdPDF download" @default.
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