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- W2806227536 abstract "Abstract Objective To evaluate plaque removal efficacy of dentifrices containing sodium bicarbonate (NaHCO 3 ) compared with a non-NaHCO 3 dentifrice after a single-timed brushing. Materials and methods A randomised, controlled, examiner-blinded, four-period, crossover study in 56 adults with a mean whole-mouth plaque index of ≥2.00 (six site modification of Turesky modification of Quigley-Hein Plaque Index [TPI]). Subjects brushed once for one timed minute with a 67% NaHCO 3 dentifrice with herbs; a 67% NaHCO 3 dentifrice without herbs; a 62% NaHCO 3 dentifrice with herbs; or a non-NaHCO 3 dentifrice without herbs. All contained 923 p.p.m. fluoride as sodium fluoride. Pre- and post-brushing plaque assessments were performed. Results Mean TPI score decreased from pre- to post-brushing with all treatments. There were statistically significantly greater reductions in plaque for NaHCO 3 dentifrices compared to non-NaHCO 3 ( p < 0.0001 for all) with no significant differences between NaHCO 3 -containing dentifrices. A post hoc analysis of plaque removal from different oral areas showed statistically significant differences in favour of the NaHCO 3 dentifrices over the non-NaHCO 3 dentifrice for almost all surfaces. No adverse events were reported. Discussion and conclusion Plaque removal was significantly greater with NaHCO 3 -containing dentifrices compared with a non-NaHCO 3 dentifrice after a single, timed brushing. There was no effect of herbal tinctures. This study was registered at ClincalTrials.org: NCT03285984." @default.
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- W2806227536 date "2018-06-04" @default.
- W2806227536 modified "2023-10-13" @default.
- W2806227536 title "A randomised controlled trial to evaluate the plaque removal efficacy of sodium bicarbonate dentifrices in a single brushing clinical model" @default.
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- W2806227536 doi "https://doi.org/10.1038/s41405-018-0003-7" @default.
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