FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2806228790> ?p ?o ?g. }

• W2806228790 abstract "Neuropathic pain (NP), defined as pain initiated or caused by a primary lesion or dysfunction in the nervous system, is a debilitating chronic pain condition often resulting from cancer treatment. Among cancer patients, neuropathy during cancer treatment is a predisposing event for NP. To identify genetic variants influencing the development of NP, we conducted a genome-wide association study in 1,043 patients with squamous cell carcinoma of the head and neck, based on 714,494 tagging single-nucleotide polymorphisms (SNPs) (130 cases, 913 controls). About 12.5% of the patients, who previously had cancer treatment, had neuropathy-associated diagnoses, as defined using the ICD-9/ICD-10 codes. We identified four common SNPs representing four genomic regions: 7q22.3 (rs10950641; SNX8; P = 3.39 × 10-14), 19p13.2 (rs4804217; PCP2; P = 2.95 × 10-9), 3q27.3 (rs6796803; KNG1; P = 6.42 × 10-9) and 15q22.2 (rs4775319; RORA; P = 1.02 × 10-8), suggesting SNX8, PCP2, KNG1 and RORA might be novel target genes for NP in patients with head and neck cancer. Future experimental validation to explore physiological effects of the identified SNPs will provide a better understanding of the biological mechanisms underlying NP and may provide insights into novel therapeutic targets for treatment and management of NP." @default.
• W2806228790 created "2018-06-13" @default.
• W2806228790 creator A5004491112 @default.
• W2806228790 creator A5013302356 @default.
• W2806228790 creator A5024544988 @default.
• W2806228790 creator A5032764121 @default.
• W2806228790 creator A5048298615 @default.
• W2806228790 creator A5077244830 @default.
• W2806228790 creator A5081791823 @default.
• W2806228790 date "2018-06-08" @default.
• W2806228790 modified "2023-10-18" @default.
• W2806228790 title "Genome-wide association study identifies genes associated with neuropathy in patients with head and neck cancer" @default.
• W2806228790 cites W1573473244 @default.
• W2806228790 cites W1902885317 @default.
• W2806228790 cites W1904012459 @default.
• W2806228790 cites W1969715461 @default.
• W2806228790 cites W1976841572 @default.
• W2806228790 cites W1994436475 @default.
• W2806228790 cites W2012016911 @default.
• W2806228790 cites W2019560470 @default.
• W2806228790 cites W2022910985 @default.
• W2806228790 cites W2024995064 @default.
• W2806228790 cites W2031653487 @default.
• W2806228790 cites W2036307272 @default.
• W2806228790 cites W2052773849 @default.
• W2806228790 cites W2057828422 @default.
• W2806228790 cites W2058925305 @default.
• W2806228790 cites W2074032101 @default.
• W2806228790 cites W2076993465 @default.
• W2806228790 cites W2083674203 @default.
• W2806228790 cites W2085477034 @default.
• W2806228790 cites W2103017472 @default.
• W2806228790 cites W2104549677 @default.
• W2806228790 cites W2123185585 @default.
• W2806228790 cites W2130163314 @default.
• W2806228790 cites W2146108629 @default.
• W2806228790 cites W2147775746 @default.
• W2806228790 cites W2161633633 @default.
• W2806228790 cites W2162143298 @default.
• W2806228790 cites W2168535519 @default.
• W2806228790 cites W2346133648 @default.
• W2806228790 cites W2527286765 @default.
• W2806228790 cites W2592976233 @default.
• W2806228790 cites W2604808360 @default.
• W2806228790 cites W2613085272 @default.
• W2806228790 cites W2625687193 @default.
• W2806228790 cites W2767631641 @default.
• W2806228790 cites W4247894309 @default.
• W2806228790 doi "https://doi.org/10.1038/s41598-018-27070-4" @default.
• W2806228790 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5993794" @default.
• W2806228790 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29884837" @default.
• W2806228790 hasPublicationYear "2018" @default.
• W2806228790 type Work @default.
• W2806228790 sameAs 2806228790 @default.
• W2806228790 citedByCount "15" @default.
• W2806228790 countsByYear W28062287902018 @default.
• W2806228790 countsByYear W28062287902019 @default.
• W2806228790 countsByYear W28062287902020 @default.
• W2806228790 countsByYear W28062287902021 @default.
• W2806228790 countsByYear W28062287902022 @default.
• W2806228790 countsByYear W28062287902023 @default.
• W2806228790 crossrefType "journal-article" @default.
• W2806228790 hasAuthorship W2806228790A5004491112 @default.
• W2806228790 hasAuthorship W2806228790A5013302356 @default.
• W2806228790 hasAuthorship W2806228790A5024544988 @default.
• W2806228790 hasAuthorship W2806228790A5032764121 @default.
• W2806228790 hasAuthorship W2806228790A5048298615 @default.
• W2806228790 hasAuthorship W2806228790A5077244830 @default.
• W2806228790 hasAuthorship W2806228790A5081791823 @default.
• W2806228790 hasBestOaLocation W28062287901 @default.
• W2806228790 hasConcept C104317684 @default.
• W2806228790 hasConcept C106208931 @default.
• W2806228790 hasConcept C121608353 @default.
• W2806228790 hasConcept C126322002 @default.
• W2806228790 hasConcept C135763542 @default.
• W2806228790 hasConcept C141231307 @default.
• W2806228790 hasConcept C153209595 @default.
• W2806228790 hasConcept C2776530083 @default.
• W2806228790 hasConcept C2776833033 @default.
• W2806228790 hasConcept C2777107010 @default.
• W2806228790 hasConcept C54355233 @default.
• W2806228790 hasConcept C60644358 @default.
• W2806228790 hasConcept C71924100 @default.
• W2806228790 hasConcept C86803240 @default.
• W2806228790 hasConcept C98274493 @default.
• W2806228790 hasConceptScore W2806228790C104317684 @default.
• W2806228790 hasConceptScore W2806228790C106208931 @default.
• W2806228790 hasConceptScore W2806228790C121608353 @default.
• W2806228790 hasConceptScore W2806228790C126322002 @default.
• W2806228790 hasConceptScore W2806228790C135763542 @default.
• W2806228790 hasConceptScore W2806228790C141231307 @default.
• W2806228790 hasConceptScore W2806228790C153209595 @default.
• W2806228790 hasConceptScore W2806228790C2776530083 @default.
• W2806228790 hasConceptScore W2806228790C2776833033 @default.
• W2806228790 hasConceptScore W2806228790C2777107010 @default.
• W2806228790 hasConceptScore W2806228790C54355233 @default.
• W2806228790 hasConceptScore W2806228790C60644358 @default.
• W2806228790 hasConceptScore W2806228790C71924100 @default.
• W2806228790 hasConceptScore W2806228790C86803240 @default.
• W2806228790 hasConceptScore W2806228790C98274493 @default.

• next