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- W2806236646 abstract "Whole genome sequencing of actinomycetes has uncovered a new immense realm of microbial chemistry and biology. Most biosynthetic gene clusters present in genomes were found to remain “silent” under standard cultivation conditions. Some small molecules—chemical elicitors—can be used to induce the biosynthesis of antibiotics in actinobacteria and to expand the chemical diversity of secondary metabolites. Here, we outline a brief account of the basic principles of the search for regulators of this type and their application." @default.
- W2806236646 created "2018-06-13" @default.
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- W2806236646 date "2018-06-08" @default.
- W2806236646 modified "2023-10-05" @default.
- W2806236646 title "Chemical Elicitors of Antibiotic Biosynthesis in Actinomycetes" @default.
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- W2806236646 doi "https://doi.org/10.3390/microorganisms6020052" @default.
- W2806236646 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6027282" @default.
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