FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2806262278> ?p ?o ?g. }

• W2806262278 abstract "Insufficient sleep increases blood pressure. However, the effects of milder, highly prevalent but frequently neglected sleep disturbances, including poor sleep quality and insomnia, on vascular health in women are unclear. We investigated whether poor sleep patterns are associated with blood pressure and endothelial inflammation in a diverse sample of women.Women who participated in the ongoing American Heart Association Go Red for Women Strategically Focused Research Network were studied (n=323, 57% minority, mean age=39±17 years, range=20-79 years). Sleep duration, sleep quality, and time to sleep onset were assessed using the Pittsburgh Sleep Quality Index (score ≥5=poor sleep quality). Risk for obstructive sleep apnea was evaluated using the Berlin questionnaire, and insomnia was assessed using the Insomnia Severity Index. In a subset of women who participated in the basic study (n=26), sleep duration was assessed objectively using actigraphy, and endothelial inflammation was assessed directly in harvested endothelial cells by measuring nuclear translocation of nuclear factor kappa B. Vascular reactivity was measured by brachial artery flow-mediated dilation (n=26). Systolic and diastolic blood pressure were measured by trained personnel (n=323). Multivariable linear regressions were used to evaluate associations between sleep patterns and blood pressure, nuclear factor kappa B, and flow-mediated dilation. Mean sleep duration was 6.8±1.3 hours/night in the population study and 7.5±1.1 hour/night in the basic study. In the population study sample, 50% had poor sleep quality versus 23% in the basic study, and 37% had some level of insomnia versus 15% in the basic study. Systolic blood pressure was associated directly with poor sleep quality, and diastolic blood pressure was of borderline significance with obstructive sleep apnea risk after adjusting for confounders (P=0.04 and P=0.08, respectively). Poor sleep quality was associated with endothelial nuclear factor kappa B activation (β=30.6; P=0.03). Insomnia and longer sleep onset latency were also associated with endothelial nuclear factor kappa B activation (β=27.6; P=0.002 and β=8.26; P=0.02, respectively). No evidence was found for an association between sleep and flow-mediated dilation.These findings provide direct evidence that common but frequently neglected sleep disturbances such as poor sleep quality and insomnia are associated with increased blood pressure and vascular inflammation even in the absence of inadequate sleep duration in women.URL: https://www.clinicaltrials.gov. Unique identifier: NCT02835261." @default.
• W2806262278 created "2018-06-13" @default.
• W2806262278 creator A5018291612 @default.
• W2806262278 creator A5023089061 @default.
• W2806262278 creator A5024203493 @default.
• W2806262278 creator A5048647723 @default.
• W2806262278 creator A5049061559 @default.
• W2806262278 creator A5055029890 @default.
• W2806262278 creator A5076657016 @default.
• W2806262278 date "2018-06-19" @default.
• W2806262278 modified "2023-10-02" @default.
• W2806262278 title "Effects of Inadequate Sleep on Blood Pressure and Endothelial Inflammation in Women: Findings From the American Heart Association Go Red for Women Strategically Focused Research Network" @default.
• W2806262278 cites W1555489744 @default.
• W2806262278 cites W1586093278 @default.
• W2806262278 cites W182910583 @default.
• W2806262278 cites W1965984702 @default.
• W2806262278 cites W1966544093 @default.
• W2806262278 cites W1969887065 @default.
• W2806262278 cites W1976234290 @default.
• W2806262278 cites W1996391039 @default.
• W2806262278 cites W1996684305 @default.
• W2806262278 cites W2003279143 @default.
• W2806262278 cites W2003982930 @default.
• W2806262278 cites W2009254187 @default.
• W2806262278 cites W2011356460 @default.
• W2806262278 cites W2011871724 @default.
• W2806262278 cites W2034556696 @default.
• W2806262278 cites W2035172218 @default.
• W2806262278 cites W2050887764 @default.
• W2806262278 cites W2061658994 @default.
• W2806262278 cites W2070142747 @default.
• W2806262278 cites W2082307168 @default.
• W2806262278 cites W2084079665 @default.
• W2806262278 cites W2096701216 @default.
• W2806262278 cites W2097326876 @default.
• W2806262278 cites W2097837926 @default.
• W2806262278 cites W2117238388 @default.
• W2806262278 cites W2117834225 @default.
• W2806262278 cites W2121622875 @default.
• W2806262278 cites W2127331384 @default.
• W2806262278 cites W2135405891 @default.
• W2806262278 cites W2138753856 @default.
• W2806262278 cites W2142936302 @default.
• W2806262278 cites W2144757081 @default.
• W2806262278 cites W2150429350 @default.
• W2806262278 cites W2151487996 @default.
• W2806262278 cites W2155939240 @default.
• W2806262278 cites W2156852637 @default.
• W2806262278 cites W2160801689 @default.
• W2806262278 cites W2160870200 @default.
• W2806262278 cites W2165003252 @default.
• W2806262278 cites W2190946050 @default.
• W2806262278 cites W2232303328 @default.
• W2806262278 cites W2341196779 @default.
• W2806262278 cites W2497443202 @default.
• W2806262278 cites W2555637497 @default.
• W2806262278 cites W2731278733 @default.
• W2806262278 cites W4233235818 @default.
• W2806262278 cites W4240261103 @default.
• W2806262278 cites W4245299678 @default.
• W2806262278 cites W623924200 @default.
• W2806262278 cites W762533598 @default.
• W2806262278 doi "https://doi.org/10.1161/jaha.118.008590" @default.
• W2806262278 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6220553" @default.
• W2806262278 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29886425" @default.
• W2806262278 hasPublicationYear "2018" @default.
• W2806262278 type Work @default.
• W2806262278 sameAs 2806262278 @default.
• W2806262278 citedByCount "40" @default.
• W2806262278 countsByYear W28062622782019 @default.
• W2806262278 countsByYear W28062622782020 @default.
• W2806262278 countsByYear W28062622782021 @default.
• W2806262278 countsByYear W28062622782022 @default.
• W2806262278 countsByYear W28062622782023 @default.
• W2806262278 crossrefType "journal-article" @default.
• W2806262278 hasAuthorship W2806262278A5018291612 @default.
• W2806262278 hasAuthorship W2806262278A5023089061 @default.
• W2806262278 hasAuthorship W2806262278A5024203493 @default.
• W2806262278 hasAuthorship W2806262278A5048647723 @default.
• W2806262278 hasAuthorship W2806262278A5049061559 @default.
• W2806262278 hasAuthorship W2806262278A5055029890 @default.
• W2806262278 hasAuthorship W2806262278A5076657016 @default.
• W2806262278 hasBestOaLocation W28062622781 @default.
• W2806262278 hasConcept C118552586 @default.
• W2806262278 hasConcept C121446783 @default.
• W2806262278 hasConcept C126322002 @default.
• W2806262278 hasConcept C164705383 @default.
• W2806262278 hasConcept C1862650 @default.
• W2806262278 hasConcept C2776006263 @default.
• W2806262278 hasConcept C2776245837 @default.
• W2806262278 hasConcept C2777604165 @default.
• W2806262278 hasConcept C2778996325 @default.
• W2806262278 hasConcept C2781210498 @default.
• W2806262278 hasConcept C2908647359 @default.
• W2806262278 hasConcept C2983189541 @default.
• W2806262278 hasConcept C71924100 @default.
• W2806262278 hasConcept C84393581 @default.
• W2806262278 hasConcept C99454951 @default.
• W2806262278 hasConceptScore W2806262278C118552586 @default.
• W2806262278 hasConceptScore W2806262278C121446783 @default.

• next