FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2806448615> ?p ?o ?g. }

• W2806448615 endingPage "636" @default.
• W2806448615 startingPage "630" @default.
• W2806448615 abstract "Paracoccidioidomycosis (PCM) is a systemic mycosis endemic in Latin America, caused by Paracoccidioides spp. A limited number of antifungal agents are available and the search for new compounds has increased. Additionally, nanostructured lipid system (NLS) has emmerged as an interesting strategy to carrier compounds for the treatment of mycosis. In this work, the antifungal efficacy and toxicity of dodecyl gallate (DOD) associated with a NLS was evaluated through in vitro and in vivo tests. DOD showed good in vitro antifungal activity and low toxicity in lung fibroblasts and zebrafish embryos, but no antifungal efficacy in infected mice, which may have been a result of low bioavailability. On the other hand, the association of DOD + NLS was beneficial and resulted in lower toxicity in lung fibroblasts and zebrafish embryos. In addition, NLS + DOD promoted a significant reduction in the fungal burden of mice lungs and could be a potential therapeutic option against PCM." @default.
• W2806448615 created "2018-06-13" @default.
• W2806448615 creator A5001173290 @default.
• W2806448615 creator A5012705132 @default.
• W2806448615 creator A5015469685 @default.
• W2806448615 creator A5036029742 @default.
• W2806448615 creator A5042000856 @default.
• W2806448615 creator A5048423669 @default.
• W2806448615 creator A5055215019 @default.
• W2806448615 creator A5056606353 @default.
• W2806448615 creator A5061051369 @default.
• W2806448615 creator A5069747215 @default.
• W2806448615 creator A5070797450 @default.
• W2806448615 creator A5084202128 @default.
• W2806448615 creator A5087935552 @default.
• W2806448615 date "2018-08-01" @default.
• W2806448615 modified "2023-10-18" @default.
• W2806448615 title "Potential of the association of dodecyl gallate with nanostructured lipid system as a treatment for paracoccidioidomycosis: In vitro and in vivo efficacy and toxicity" @default.
• W2806448615 cites W1567006673 @default.
• W2806448615 cites W1775525639 @default.
• W2806448615 cites W1803284666 @default.
• W2806448615 cites W1896191564 @default.
• W2806448615 cites W1975733685 @default.
• W2806448615 cites W1981239255 @default.
• W2806448615 cites W1988159995 @default.
• W2806448615 cites W1990275638 @default.
• W2806448615 cites W1997330469 @default.
• W2806448615 cites W2005790067 @default.
• W2806448615 cites W2026505095 @default.
• W2806448615 cites W2031673647 @default.
• W2806448615 cites W2035079262 @default.
• W2806448615 cites W2035976525 @default.
• W2806448615 cites W2055593282 @default.
• W2806448615 cites W2059848382 @default.
• W2806448615 cites W2062280806 @default.
• W2806448615 cites W2070088559 @default.
• W2806448615 cites W2085667520 @default.
• W2806448615 cites W2091548409 @default.
• W2806448615 cites W2104935728 @default.
• W2806448615 cites W2107461063 @default.
• W2806448615 cites W2111483559 @default.
• W2806448615 cites W2113046994 @default.
• W2806448615 cites W2113460689 @default.
• W2806448615 cites W2120490338 @default.
• W2806448615 cites W2125447929 @default.
• W2806448615 cites W2128133357 @default.
• W2806448615 cites W2129904084 @default.
• W2806448615 cites W2136283078 @default.
• W2806448615 cites W2141255365 @default.
• W2806448615 cites W2143320924 @default.
• W2806448615 cites W2154384649 @default.
• W2806448615 cites W2159366341 @default.
• W2806448615 cites W2174642539 @default.
• W2806448615 cites W2259821937 @default.
• W2806448615 cites W2332193912 @default.
• W2806448615 cites W2407993699 @default.
• W2806448615 cites W2519867867 @default.
• W2806448615 cites W2581889147 @default.
• W2806448615 cites W2996631976 @default.
• W2806448615 cites W4213016631 @default.
• W2806448615 doi "https://doi.org/10.1016/j.ijpharm.2018.06.013" @default.
• W2806448615 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29883792" @default.
• W2806448615 hasPublicationYear "2018" @default.
• W2806448615 type Work @default.
• W2806448615 sameAs 2806448615 @default.
• W2806448615 citedByCount "13" @default.
• W2806448615 countsByYear W28064486152019 @default.
• W2806448615 countsByYear W28064486152020 @default.
• W2806448615 countsByYear W28064486152021 @default.
• W2806448615 countsByYear W28064486152022 @default.
• W2806448615 countsByYear W28064486152023 @default.
• W2806448615 crossrefType "journal-article" @default.
• W2806448615 hasAuthorship W2806448615A5001173290 @default.
• W2806448615 hasAuthorship W2806448615A5012705132 @default.
• W2806448615 hasAuthorship W2806448615A5015469685 @default.
• W2806448615 hasAuthorship W2806448615A5036029742 @default.
• W2806448615 hasAuthorship W2806448615A5042000856 @default.
• W2806448615 hasAuthorship W2806448615A5048423669 @default.
• W2806448615 hasAuthorship W2806448615A5055215019 @default.
• W2806448615 hasAuthorship W2806448615A5056606353 @default.
• W2806448615 hasAuthorship W2806448615A5061051369 @default.
• W2806448615 hasAuthorship W2806448615A5069747215 @default.
• W2806448615 hasAuthorship W2806448615A5070797450 @default.
• W2806448615 hasAuthorship W2806448615A5084202128 @default.
• W2806448615 hasAuthorship W2806448615A5087935552 @default.
• W2806448615 hasBestOaLocation W28064486152 @default.
• W2806448615 hasConcept C104317684 @default.
• W2806448615 hasConcept C126322002 @default.
• W2806448615 hasConcept C150903083 @default.
• W2806448615 hasConcept C202751555 @default.
• W2806448615 hasConcept C203014093 @default.
• W2806448615 hasConcept C207001950 @default.
• W2806448615 hasConcept C2776878037 @default.
• W2806448615 hasConcept C2779108831 @default.
• W2806448615 hasConcept C2779548794 @default.
• W2806448615 hasConcept C2780651595 @default.
• W2806448615 hasConcept C29730261 @default.
• W2806448615 hasConcept C55493867 @default.

• next