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- W2806459001 abstract "Abstract A new family of polystyrene‐supported cis ‐4‐hydroxydiphenylprolinol silyl ethers has been prepared, and the resulting polymers have been evaluated as organocatalysts to promote the tandem reaction between N ‐protected hydroxylamines and α,β‐unsaturated aldehydes in batch and flow. The new PS‐supported catalysts compare favorably with well‐established immobilized Jørgensen‐Hayashi catalysts, affording 5‐hydroxyisoxazolidines as single diastereoisomers with high enantioselectivities and good yields (up to 83% yield, up to 99% ee). magnified image" @default.
- W2806459001 created "2018-06-13" @default.
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- W2806459001 date "2018-06-22" @default.
- W2806459001 modified "2023-10-12" @default.
- W2806459001 title "Immobilization of <i>cis</i> -4-Hydroxydiphenylprolinol Silyl Ethers onto Polystyrene. Application in the Catalytic Enantioselective Synthesis of 5-Hydroxyisoxazolidines in Batch and Flow" @default.
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- W2806459001 doi "https://doi.org/10.1002/adsc.201800572" @default.
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