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- W2806578461 abstract "Abstract DEMETER-like DNA glycosylases (DMLs) initiate the base excision repair-dependent DNA demethylation to regulate a wide range of biological processes in plants. Six putative SmDML genes, termed SmDML1 – SmDML6 , were identified from the genome of S . miltiorrhiza , an emerging model plant for Traditional Chinese Medicine (TCM) studies. Integrated analysis of gene structures, sequence features, conserved domains and motifs, phylogenetic analysis and differential expression showed the conservation and divergence of SmDMLs . SmDML1 , SmDML2 and SmDML4 were significantly down-regulated by the treatment of 5Aza-dC, a general DNA methylation inhibitor, suggesting involvement of SmDMLs in genome DNA methylation change. SmDML1 was predicted and experimentally validated to be target of Smi-miR7972. Computational analysis of forty whole genome sequences and almost all of RNA-seq data from Lamiids revealed that MIR7972s were only distributed in some plants of the three orders, including Lamiales, Solanales and Boraginales, and the number of MIR7972 genes varied among species. It suggests that MIR7972 genes underwent expansion and loss during the evolution of some Lamiids species. Phylogenetic analysis of MIR7972s showed closer evolutionary relationships between MIR7972s in Boraginales and Solanales in comparison with Lamiales. These results provide a valuable resource for elucidating DNA demethylation mechanism in S . miltiorrhiza ." @default.
- W2806578461 created "2018-06-13" @default.
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- W2806578461 creator A5034953327 @default.
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- W2806578461 date "2018-05-08" @default.
- W2806578461 modified "2023-10-14" @default.
- W2806578461 title "Systematic analysis of DEMETER-like DNA glycosylase genes shows lineage-specific Smi-miR7972 involved in SmDML1 regulation in Salvia miltiorrhiza" @default.
- W2806578461 cites W1191273493 @default.
- W2806578461 cites W1495519601 @default.
- W2806578461 cites W1500702901 @default.
- W2806578461 cites W1531079516 @default.
- W2806578461 cites W1557790541 @default.
- W2806578461 cites W1912918241 @default.
- W2806578461 cites W1967543716 @default.
- W2806578461 cites W1976626368 @default.
- W2806578461 cites W1977171359 @default.
- W2806578461 cites W1984251741 @default.
- W2806578461 cites W1987289807 @default.
- W2806578461 cites W1997413633 @default.
- W2806578461 cites W2001165159 @default.
- W2806578461 cites W2005019977 @default.
- W2806578461 cites W2006247279 @default.
- W2806578461 cites W2018249152 @default.
- W2806578461 cites W2022030369 @default.
- W2806578461 cites W2024556021 @default.
- W2806578461 cites W2026343134 @default.
- W2806578461 cites W2036135612 @default.
- W2806578461 cites W2050507681 @default.
- W2806578461 cites W2052014103 @default.
- W2806578461 cites W2062361319 @default.
- W2806578461 cites W2064489231 @default.
- W2806578461 cites W2064916061 @default.
- W2806578461 cites W2071758876 @default.
- W2806578461 cites W2080335963 @default.
- W2806578461 cites W2080667183 @default.
- W2806578461 cites W2082341355 @default.
- W2806578461 cites W2084144075 @default.
- W2806578461 cites W2089812281 @default.
- W2806578461 cites W2091601313 @default.
- W2806578461 cites W2091658754 @default.
- W2806578461 cites W2091722627 @default.
- W2806578461 cites W2092303564 @default.
- W2806578461 cites W2100305481 @default.
- W2806578461 cites W2103444581 @default.
- W2806578461 cites W2104184327 @default.
- W2806578461 cites W2107277218 @default.
- W2806578461 cites W2115042004 @default.
- W2806578461 cites W2121673931 @default.
- W2806578461 cites W2122862305 @default.
- W2806578461 cites W2124985265 @default.
- W2806578461 cites W2132606090 @default.
- W2806578461 cites W2135015580 @default.
- W2806578461 cites W2135640258 @default.
- W2806578461 cites W2137244077 @default.
- W2806578461 cites W2141026227 @default.
- W2806578461 cites W2141157874 @default.
- W2806578461 cites W2141521804 @default.
- W2806578461 cites W2144177541 @default.
- W2806578461 cites W2145883554 @default.
- W2806578461 cites W2147465115 @default.
- W2806578461 cites W2150960321 @default.
- W2806578461 cites W2151115617 @default.
- W2806578461 cites W2154066769 @default.
- W2806578461 cites W2155772493 @default.
- W2806578461 cites W2156825952 @default.
- W2806578461 cites W2158714788 @default.
- W2806578461 cites W2160069833 @default.
- W2806578461 cites W2161704266 @default.
- W2806578461 cites W2162170048 @default.
- W2806578461 cites W2169741121 @default.
- W2806578461 cites W2170828323 @default.
- W2806578461 cites W2173784328 @default.
- W2806578461 cites W2188601066 @default.
- W2806578461 cites W2192080449 @default.
- W2806578461 cites W2237793099 @default.
- W2806578461 cites W2269103384 @default.
- W2806578461 cites W2310808048 @default.
- W2806578461 cites W2311203695 @default.
- W2806578461 cites W2343331236 @default.
- W2806578461 cites W2360098018 @default.
- W2806578461 cites W2465901535 @default.
- W2806578461 cites W2486512244 @default.
- W2806578461 cites W2710331162 @default.
- W2806578461 cites W2775809156 @default.
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- W2806578461 doi "https://doi.org/10.1038/s41598-018-25315-w" @default.
- W2806578461 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5940787" @default.
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- W2806578461 hasPublicationYear "2018" @default.
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