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- W2806670887 endingPage "58" @default.
- W2806670887 startingPage "58" @default.
- W2806670887 abstract "Members of the TRPM (“Melastatin”) family fall into the subclass of the TRP channels having varying permeability to Ca2+ and Mg2+, with three members of the TRPM family being chanzymes, which contain C-terminal enzyme domains. The role of different TRPM members has been shown in various cancers such as prostate cancer for mostly TRPM8 and TRPM2, breast cancer for mostly TRPM2 and TRPM7, and pancreatic cancer for TRPM2/7/8 channels. The role of TRPM5 channels has been shown in lung cancer, TRPM1 in melanoma, and TRPM4 channel in prostate cancer as well. Thus, the TRPM family of channels may represent an appealing target for the anticancer therapy." @default.
- W2806670887 created "2018-06-13" @default.
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- W2806670887 creator A5059745807 @default.
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- W2806670887 date "2018-06-07" @default.
- W2806670887 modified "2023-10-17" @default.
- W2806670887 title "TRPM Family Channels in Cancer" @default.
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- W2806670887 doi "https://doi.org/10.3390/ph11020058" @default.
- W2806670887 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6027338" @default.
- W2806670887 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29875336" @default.
- W2806670887 hasPublicationYear "2018" @default.
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