Matches in SemOpenAlex for { <https://semopenalex.org/work/W2806804067> ?p ?o ?g. }
- W2806804067 endingPage "175883591877703" @default.
- W2806804067 startingPage "175883591877703" @default.
- W2806804067 abstract "Background: Pressurized intraperitoneal aerosol chemotherapy (PIPAC) is a laparoscopy-guided administration of aerosolized chemotherapy. PIPAC seems to improve objective tumor response, survival and quality of life in patients with peritoneal metastasis. We assessed feasibility and efficacy of PIPAC in patients with peritoneal metastasis (PM). Methods: Patients were included in a prospective PIPAC protocol. Patients with colorectal PM were treated with oxaliplatin, patients with other primary tumors were treated with cisplatin and doxorubicin. Any chemotherapy exposure for healthcare workers was monitored by environmental and biological sampling. Feasibility was quantified by completion and complication rates. Response evaluation was documented by the peritoneal regression grading score (PRGS) and by peritoneal lavage cytology. Biopsy sites were marked by clips. Quality of life questionnaires were collected at baseline and after 60, 120 and 180 days. Results: A total of 35 patients with PM were treated with a median of three PIPAC procedures (range 1–9). Intraperitoneal access and completion of PIPAC was achieved in all patients. Few complications and adverse events were noted. There was no risk of chemotherapy exposure for healthcare workers. The mean PRGS was reduced significantly and a reduction of the PRGS was seen in 67% of the patients. Conversion from positive to negative cytology was achieved in 23% of the patients. Quality of life was stabilized from baseline to day 60. Conclusions: PIPAC is feasible and well tolerated, may stabilize the quality of life in patients with end-stage PM and may induce histological and cytological regression. This study is registered at www.clinicaltrials.gov [ClinicalTrials.gov identifier: NCT02320448]." @default.
- W2806804067 created "2018-06-13" @default.
- W2806804067 creator A5053042879 @default.
- W2806804067 creator A5064447198 @default.
- W2806804067 creator A5068848511 @default.
- W2806804067 creator A5069535705 @default.
- W2806804067 creator A5070827313 @default.
- W2806804067 creator A5091308274 @default.
- W2806804067 date "2018-01-01" @default.
- W2806804067 modified "2023-10-03" @default.
- W2806804067 title "Prospective, single-center implementation and response evaluation of pressurized intraperitoneal aerosol chemotherapy (PIPAC) for peritoneal metastasis" @default.
- W2806804067 cites W1853593785 @default.
- W2806804067 cites W1927044883 @default.
- W2806804067 cites W1970515848 @default.
- W2806804067 cites W1978011918 @default.
- W2806804067 cites W1980661013 @default.
- W2806804067 cites W2019607817 @default.
- W2806804067 cites W2020758943 @default.
- W2806804067 cites W2027756998 @default.
- W2806804067 cites W2034017747 @default.
- W2806804067 cites W2034903741 @default.
- W2806804067 cites W2051099595 @default.
- W2806804067 cites W2060590865 @default.
- W2806804067 cites W2080853165 @default.
- W2806804067 cites W2087230876 @default.
- W2806804067 cites W2089803323 @default.
- W2806804067 cites W2104304800 @default.
- W2806804067 cites W2108105961 @default.
- W2806804067 cites W2117190139 @default.
- W2806804067 cites W2118514776 @default.
- W2806804067 cites W2133768270 @default.
- W2806804067 cites W2147428735 @default.
- W2806804067 cites W2159124192 @default.
- W2806804067 cites W2159140139 @default.
- W2806804067 cites W2161579588 @default.
- W2806804067 cites W2167571044 @default.
- W2806804067 cites W2170008162 @default.
- W2806804067 cites W2194281569 @default.
- W2806804067 cites W2287798134 @default.
- W2806804067 cites W2344894825 @default.
- W2806804067 cites W2415137199 @default.
- W2806804067 cites W2475170675 @default.
- W2806804067 cites W2524247262 @default.
- W2806804067 cites W2531203326 @default.
- W2806804067 cites W2556306852 @default.
- W2806804067 cites W2590370975 @default.
- W2806804067 cites W2605936377 @default.
- W2806804067 cites W2615552839 @default.
- W2806804067 cites W2760472470 @default.
- W2806804067 cites W2793160759 @default.
- W2806804067 cites W4241573849 @default.
- W2806804067 cites W4292528108 @default.
- W2806804067 doi "https://doi.org/10.1177/1758835918777036" @default.
- W2806804067 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/5985602" @default.
- W2806804067 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29899763" @default.
- W2806804067 hasPublicationYear "2018" @default.
- W2806804067 type Work @default.
- W2806804067 sameAs 2806804067 @default.
- W2806804067 citedByCount "55" @default.
- W2806804067 countsByYear W28068040672018 @default.
- W2806804067 countsByYear W28068040672019 @default.
- W2806804067 countsByYear W28068040672020 @default.
- W2806804067 countsByYear W28068040672021 @default.
- W2806804067 countsByYear W28068040672022 @default.
- W2806804067 countsByYear W28068040672023 @default.
- W2806804067 crossrefType "journal-article" @default.
- W2806804067 hasAuthorship W2806804067A5053042879 @default.
- W2806804067 hasAuthorship W2806804067A5064447198 @default.
- W2806804067 hasAuthorship W2806804067A5068848511 @default.
- W2806804067 hasAuthorship W2806804067A5069535705 @default.
- W2806804067 hasAuthorship W2806804067A5070827313 @default.
- W2806804067 hasAuthorship W2806804067A5091308274 @default.
- W2806804067 hasBestOaLocation W28068040671 @default.
- W2806804067 hasConcept C121608353 @default.
- W2806804067 hasConcept C126322002 @default.
- W2806804067 hasConcept C141071460 @default.
- W2806804067 hasConcept C159110408 @default.
- W2806804067 hasConcept C188816634 @default.
- W2806804067 hasConcept C197934379 @default.
- W2806804067 hasConcept C2776694085 @default.
- W2806804067 hasConcept C2779013556 @default.
- W2806804067 hasConcept C2779951463 @default.
- W2806804067 hasConcept C71924100 @default.
- W2806804067 hasConceptScore W2806804067C121608353 @default.
- W2806804067 hasConceptScore W2806804067C126322002 @default.
- W2806804067 hasConceptScore W2806804067C141071460 @default.
- W2806804067 hasConceptScore W2806804067C159110408 @default.
- W2806804067 hasConceptScore W2806804067C188816634 @default.
- W2806804067 hasConceptScore W2806804067C197934379 @default.
- W2806804067 hasConceptScore W2806804067C2776694085 @default.
- W2806804067 hasConceptScore W2806804067C2779013556 @default.
- W2806804067 hasConceptScore W2806804067C2779951463 @default.
- W2806804067 hasConceptScore W2806804067C71924100 @default.
- W2806804067 hasLocation W28068040671 @default.
- W2806804067 hasLocation W28068040672 @default.
- W2806804067 hasLocation W28068040673 @default.
- W2806804067 hasLocation W28068040674 @default.
- W2806804067 hasLocation W28068040675 @default.