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• W2806885331 abstract "Background: Insufficient sleep is common in daily life and can lead to cognitive impairment. Sleep disturbance also exists in neuropsychiatric diseases. However, whether and how acute and chronic sleep loss affect brain morphology remain largely unknown. Methods: We used voxel-based morphology method to study the brain structural changes during sleep deprivation (SD) at six time points of rested wakefulness, 20, 24, 32, 36 h SD, and after one night sleep in 22 healthy subjects, and in 39 patients with chronic primary insomnia relative to 39 status-matched good sleepers. Attention network and spatial memory tests were performed at each SD time point in the SD Procedure. The longitudinal data were analyzed using one-way repeated measures ANOVA, and post-hoc analysis was used to determine the between-group differences. Results: Acute SD is associated with widespread gray matter volume (GMV) changes in the thalamus, cerebellum, insula and parietal cortex. Insomnia is associated with increased GMV in temporal cortex, insula and cerebellum. Acute SD is associated with brain atrophy and as SD hours prolong more areas show reduced GMV, and after one night sleep the brain atrophy is restored and replaced by increased GMV in brain areas. SD has accumulative negative effects on attention and working memory. Conclusions: Acute SD and insomnia exhibit distinct morphological changes of GMV. SD has accumulative negative effects on brain morphology and advanced cognitive function. The altered GMV may provide neurobiological basis for attention and memory impairments following sleep loss.Sleep is less frequently studied using imaging techniques than neurological and psychiatric disorders. Whether and how acute and chronic sleep loss affect brain morphology remain largely unknown. We used voxel-based morphology method to study brain structural changes in healthy subjects over multiple time points during sleep deprivation (SD) status and in patients with chronic insomnia. We found that prolonged acute SD together with one night sleep recovery exhibits accumulative atrophic effect and recovering plasticity on brain morphology, in line with behavioral changes on attentional tasks. Furthermore, acute SD and chronic insomnia exhibit distinct morphological changes of gray matter volume (GMV) but they also share overlapping GMV changes. The altered GMV may provide structural basis for attention and memory impairments following sleep loss." @default.
• W2806885331 created "2018-06-13" @default.
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• W2806885331 date "2018-06-27" @default.
• W2806885331 modified "2023-10-15" @default.
• W2806885331 title "Plasticity and Susceptibility of Brain Morphometry Alterations to Insufficient Sleep" @default.
• W2806885331 cites W1491392377 @default.
• W2806885331 cites W1551563638 @default.
• W2806885331 cites W1729779209 @default.
• W2806885331 cites W1731183656 @default.
• W2806885331 cites W1925423442 @default.
• W2806885331 cites W1967182713 @default.
• W2806885331 cites W1969547130 @default.
• W2806885331 cites W1971639265 @default.
• W2806885331 cites W1972519049 @default.
• W2806885331 cites W1980917913 @default.
• W2806885331 cites W1982924671 @default.
• W2806885331 cites W1990101070 @default.
• W2806885331 cites W2000825257 @default.
• W2806885331 cites W2001307790 @default.
• W2806885331 cites W2002738263 @default.
• W2806885331 cites W2005371006 @default.
• W2806885331 cites W2006023779 @default.
• W2806885331 cites W2006587002 @default.
• W2806885331 cites W2009845727 @default.
• W2806885331 cites W2018107046 @default.
• W2806885331 cites W2024075025 @default.
• W2806885331 cites W2024602020 @default.
• W2806885331 cites W2026862798 @default.
• W2806885331 cites W2027141772 @default.
• W2806885331 cites W2030380798 @default.
• W2806885331 cites W2030859315 @default.
• W2806885331 cites W2039435780 @default.
• W2806885331 cites W2041354320 @default.
• W2806885331 cites W2042881727 @default.
• W2806885331 cites W2044489210 @default.
• W2806885331 cites W2045259558 @default.
• W2806885331 cites W2045382981 @default.
• W2806885331 cites W2046964445 @default.
• W2806885331 cites W2049185563 @default.
• W2806885331 cites W2052969270 @default.
• W2806885331 cites W2053587982 @default.
• W2806885331 cites W2053842462 @default.
• W2806885331 cites W2056146083 @default.
• W2806885331 cites W2056208559 @default.
• W2806885331 cites W2059018477 @default.
• W2806885331 cites W2061835082 @default.
• W2806885331 cites W2070943293 @default.
• W2806885331 cites W2071215075 @default.
• W2806885331 cites W2071400945 @default.
• W2806885331 cites W2072416063 @default.
• W2806885331 cites W2082850379 @default.
• W2806885331 cites W2085553710 @default.
• W2806885331 cites W2087675899 @default.
• W2806885331 cites W2088355742 @default.
• W2806885331 cites W2094234618 @default.
• W2806885331 cites W2095257990 @default.
• W2806885331 cites W2100354242 @default.
• W2806885331 cites W2101664081 @default.
• W2806885331 cites W2102436032 @default.
• W2806885331 cites W2110747672 @default.
• W2806885331 cites W2114613490 @default.
• W2806885331 cites W2115016824 @default.
• W2806885331 cites W2118421222 @default.
• W2806885331 cites W2119848633 @default.
• W2806885331 cites W2123643536 @default.
• W2806885331 cites W2127450768 @default.
• W2806885331 cites W2128797181 @default.
• W2806885331 cites W2129217829 @default.
• W2806885331 cites W2137367342 @default.
• W2806885331 cites W2149607015 @default.
• W2806885331 cites W2150442066 @default.
• W2806885331 cites W2150902492 @default.
• W2806885331 cites W2151487996 @default.
• W2806885331 cites W2160070901 @default.
• W2806885331 cites W2161755947 @default.
• W2806885331 cites W2163225965 @default.
• W2806885331 cites W2170332928 @default.
• W2806885331 cites W2202719344 @default.
• W2806885331 cites W2252475099 @default.
• W2806885331 cites W2316754223 @default.
• W2806885331 cites W2339404531 @default.
• W2806885331 cites W2516087592 @default.
• W2806885331 cites W2616414475 @default.
• W2806885331 cites W2619025546 @default.
• W2806885331 cites W2619879339 @default.
• W2806885331 cites W2621964557 @default.
• W2806885331 cites W2797855672 @default.
• W2806885331 cites W4230920194 @default.
• W2806885331 doi "https://doi.org/10.3389/fpsyt.2018.00266" @default.
• W2806885331 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6030367" @default.

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