FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2806886907> ?p ?o ?g. }

• W2806886907 endingPage "8" @default.
• W2806886907 startingPage "1" @default.
• W2806886907 abstract "Aim Due to increasing life expectancy, patients with breast cancer remain at risk of dying due to breast cancer over a long time. This study aims to assess the impact of age on breast cancer mortality and other cause mortality 10 years after diagnosis. Methods Postmenopausal patients with hormone-receptor positive breast cancer were included in the Tamoxifen and Exemestane Adjuvant Multinational (TEAM) trial between 2001 and 2006. Age at diagnosis was categorised as <65 years (n = 3369), 65–74 years (n = 1896) and ≥75 years (n = 854). Breast cancer mortality was assessed considering other cause mortality as competing event using competing risk analysis. Results After a median follow-up of 9.8 years (interquartile range 8.0–10.3), cumulative incidence of breast cancer mortality increased with increasing age (age <65 years, 11.7% [95% confidence interval {CI}: 10.2–13.2]; 65–74 years, 12.7% (11.2–14.2) and ≥75 years, 15.6% (13.1–18.0)). Univariate subdistribution hazard ratio (sHR) increased with increasing age (age: 65–74 years, sHR: 1.08, 95% CI: 0.92–1.27 and ≥75 years sHR: 1.30, 95% CI: 1.06–1.58, P = 0.013). Multivariable sHR adjusted for tumour and treatment characteristics increased with age but did not reach significance (age 65–74 years, sHR: 1.11, 95% CI: 0.94–1.31; ≥75 years, sHR: 1.18, 95% CI: 0.94–1.48, P = 0.055). Conclusion Ten years after diagnosis, older age at diagnosis is associated with increasing breast cancer mortality in univariate analysis, but it did not reach significance in multivariable analysis. This is not outweighed by a substantially higher other cause mortality with older age. This underlines the need to improve the balance between undertreatment and overtreatment in older patients with breast cancer. The trial was registered in International Trial Databases (ClinicalTrials.gov NCT00279448, NCT00032136, and NCT00036270; the Netherlands Trial Registry NTR267)." @default.
• W2806886907 created "2018-06-13" @default.
• W2806886907 creator A5008883508 @default.
• W2806886907 creator A5022173747 @default.
• W2806886907 creator A5025411863 @default.
• W2806886907 creator A5026031837 @default.
• W2806886907 creator A5028380474 @default.
• W2806886907 creator A5031668702 @default.
• W2806886907 creator A5031880856 @default.
• W2806886907 creator A5038448622 @default.
• W2806886907 creator A5046134229 @default.
• W2806886907 creator A5047515712 @default.
• W2806886907 creator A5051306896 @default.
• W2806886907 creator A5061242738 @default.
• W2806886907 creator A5073613763 @default.
• W2806886907 creator A5082393642 @default.
• W2806886907 date "2018-08-01" @default.
• W2806886907 modified "2023-10-12" @default.
• W2806886907 title "Impact of age on breast cancer mortality and competing causes of death at 10 years follow-up in the adjuvant TEAM trial" @default.
• W2806886907 cites W2012130476 @default.
• W2806886907 cites W2013600972 @default.
• W2806886907 cites W2032376710 @default.
• W2806886907 cites W2033710188 @default.
• W2806886907 cites W2038576667 @default.
• W2806886907 cites W2054211750 @default.
• W2806886907 cites W2054574960 @default.
• W2806886907 cites W2057847137 @default.
• W2806886907 cites W2071730981 @default.
• W2806886907 cites W2083645342 @default.
• W2806886907 cites W2088882392 @default.
• W2806886907 cites W2093381288 @default.
• W2806886907 cites W2102594212 @default.
• W2806886907 cites W2104151418 @default.
• W2806886907 cites W2113193581 @default.
• W2806886907 cites W2130337512 @default.
• W2806886907 cites W2131098741 @default.
• W2806886907 cites W2138624842 @default.
• W2806886907 cites W2139023087 @default.
• W2806886907 cites W2154117702 @default.
• W2806886907 cites W2154889318 @default.
• W2806886907 cites W2155097929 @default.
• W2806886907 cites W2159489835 @default.
• W2806886907 cites W2167600867 @default.
• W2806886907 cites W2180727225 @default.
• W2806886907 cites W2330347335 @default.
• W2806886907 cites W2738153533 @default.
• W2806886907 cites W4248736596 @default.
• W2806886907 doi "https://doi.org/10.1016/j.ejca.2018.04.009" @default.
• W2806886907 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29885375" @default.
• W2806886907 hasPublicationYear "2018" @default.
• W2806886907 type Work @default.
• W2806886907 sameAs 2806886907 @default.
• W2806886907 citedByCount "34" @default.
• W2806886907 countsByYear W28068869072019 @default.
• W2806886907 countsByYear W28068869072020 @default.
• W2806886907 countsByYear W28068869072021 @default.
• W2806886907 countsByYear W28068869072022 @default.
• W2806886907 countsByYear W28068869072023 @default.
• W2806886907 crossrefType "journal-article" @default.
• W2806886907 hasAuthorship W2806886907A5008883508 @default.
• W2806886907 hasAuthorship W2806886907A5022173747 @default.
• W2806886907 hasAuthorship W2806886907A5025411863 @default.
• W2806886907 hasAuthorship W2806886907A5026031837 @default.
• W2806886907 hasAuthorship W2806886907A5028380474 @default.
• W2806886907 hasAuthorship W2806886907A5031668702 @default.
• W2806886907 hasAuthorship W2806886907A5031880856 @default.
• W2806886907 hasAuthorship W2806886907A5038448622 @default.
• W2806886907 hasAuthorship W2806886907A5046134229 @default.
• W2806886907 hasAuthorship W2806886907A5047515712 @default.
• W2806886907 hasAuthorship W2806886907A5051306896 @default.
• W2806886907 hasAuthorship W2806886907A5061242738 @default.
• W2806886907 hasAuthorship W2806886907A5073613763 @default.
• W2806886907 hasAuthorship W2806886907A5082393642 @default.
• W2806886907 hasBestOaLocation W28068869072 @default.
• W2806886907 hasConcept C119060515 @default.
• W2806886907 hasConcept C121608353 @default.
• W2806886907 hasConcept C126322002 @default.
• W2806886907 hasConcept C207103383 @default.
• W2806886907 hasConcept C2777176818 @default.
• W2806886907 hasConcept C29456083 @default.
• W2806886907 hasConcept C44249647 @default.
• W2806886907 hasConcept C530470458 @default.
• W2806886907 hasConcept C71924100 @default.
• W2806886907 hasConceptScore W2806886907C119060515 @default.
• W2806886907 hasConceptScore W2806886907C121608353 @default.
• W2806886907 hasConceptScore W2806886907C126322002 @default.
• W2806886907 hasConceptScore W2806886907C207103383 @default.
• W2806886907 hasConceptScore W2806886907C2777176818 @default.
• W2806886907 hasConceptScore W2806886907C29456083 @default.
• W2806886907 hasConceptScore W2806886907C44249647 @default.
• W2806886907 hasConceptScore W2806886907C530470458 @default.
• W2806886907 hasConceptScore W2806886907C71924100 @default.
• W2806886907 hasFunder F4320332759 @default.
• W2806886907 hasLocation W28068869071 @default.
• W2806886907 hasLocation W28068869072 @default.
• W2806886907 hasLocation W28068869073 @default.
• W2806886907 hasLocation W28068869074 @default.
• W2806886907 hasOpenAccess W2806886907 @default.

• next