Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807006263> ?p ?o ?g. }
Showing items 1 to 71 of
71
with 100 items per page.
- W2807006263 endingPage "234" @default.
- W2807006263 startingPage "226" @default.
- W2807006263 abstract "There are no effective standard treatments for unresectable stage of liver cancer have been established. These insights lead the pursuit of targeted therapeutic strategies for reactivating apoptosis to eradicate cancer cells. It was hypothesized that active compound in the soursop leaves will be able to induce apoptosis. Objective of the study is to explore the role of novel soursop leaves active compound (SF-1603) in apoptosis induction to find a new agent for liver cancer therapy. This study was use HepG2 cell line culture seeded in DMEM / F12. There were control group and 3 intervention group given SF-1603 with different concentration. Apoptosis detection was done using Terminal deoxynucleotidyl Transferase-mediated dUTP Nick End Labeling (TUNEL) method. Statistical analyses were conducted using linear regression. The result showed the cells undergoing apoptosis in the control group less than treatment groups. There was a strong positive correlation (r=0.847) between the rate of apoptosis and a concentration of SF-1603, reflected the apoptotic effect with a dose-dependent manner. The study conclude, the novel soursop leaves active compound SF-1603 had the strong ability to induce apoptosis on liver cancer cell line culture, so it can be used as a candidate for new agent for liver cancer therapy." @default.
- W2807006263 created "2018-06-13" @default.
- W2807006263 creator A5010373764 @default.
- W2807006263 creator A5018536416 @default.
- W2807006263 creator A5067217192 @default.
- W2807006263 creator A5084870998 @default.
- W2807006263 date "2018-06-03" @default.
- W2807006263 modified "2023-10-12" @default.
- W2807006263 title "Anticancer activity of novel soursop leaves active compound (sf-1603) through apoptotic induction in liver cancer" @default.
- W2807006263 doi "https://doi.org/10.11113/mjfas.v14n2.1064" @default.
- W2807006263 hasPublicationYear "2018" @default.
- W2807006263 type Work @default.
- W2807006263 sameAs 2807006263 @default.
- W2807006263 citedByCount "4" @default.
- W2807006263 countsByYear W28070062632020 @default.
- W2807006263 countsByYear W28070062632022 @default.
- W2807006263 crossrefType "journal-article" @default.
- W2807006263 hasAuthorship W2807006263A5010373764 @default.
- W2807006263 hasAuthorship W2807006263A5018536416 @default.
- W2807006263 hasAuthorship W2807006263A5067217192 @default.
- W2807006263 hasAuthorship W2807006263A5084870998 @default.
- W2807006263 hasBestOaLocation W28070062631 @default.
- W2807006263 hasConcept C121608353 @default.
- W2807006263 hasConcept C126322002 @default.
- W2807006263 hasConcept C154113507 @default.
- W2807006263 hasConcept C185592680 @default.
- W2807006263 hasConcept C190283241 @default.
- W2807006263 hasConcept C196795494 @default.
- W2807006263 hasConcept C2776231280 @default.
- W2807006263 hasConcept C502942594 @default.
- W2807006263 hasConcept C55493867 @default.
- W2807006263 hasConcept C556039675 @default.
- W2807006263 hasConcept C71924100 @default.
- W2807006263 hasConcept C86803240 @default.
- W2807006263 hasConcept C96232424 @default.
- W2807006263 hasConcept C98274493 @default.
- W2807006263 hasConceptScore W2807006263C121608353 @default.
- W2807006263 hasConceptScore W2807006263C126322002 @default.
- W2807006263 hasConceptScore W2807006263C154113507 @default.
- W2807006263 hasConceptScore W2807006263C185592680 @default.
- W2807006263 hasConceptScore W2807006263C190283241 @default.
- W2807006263 hasConceptScore W2807006263C196795494 @default.
- W2807006263 hasConceptScore W2807006263C2776231280 @default.
- W2807006263 hasConceptScore W2807006263C502942594 @default.
- W2807006263 hasConceptScore W2807006263C55493867 @default.
- W2807006263 hasConceptScore W2807006263C556039675 @default.
- W2807006263 hasConceptScore W2807006263C71924100 @default.
- W2807006263 hasConceptScore W2807006263C86803240 @default.
- W2807006263 hasConceptScore W2807006263C96232424 @default.
- W2807006263 hasConceptScore W2807006263C98274493 @default.
- W2807006263 hasIssue "2" @default.
- W2807006263 hasLocation W28070062631 @default.
- W2807006263 hasOpenAccess W2807006263 @default.
- W2807006263 hasPrimaryLocation W28070062631 @default.
- W2807006263 hasRelatedWork W2062248725 @default.
- W2807006263 hasRelatedWork W2333726371 @default.
- W2807006263 hasRelatedWork W2358059728 @default.
- W2807006263 hasRelatedWork W2375492179 @default.
- W2807006263 hasRelatedWork W2381820491 @default.
- W2807006263 hasRelatedWork W2386169131 @default.
- W2807006263 hasRelatedWork W2391858692 @default.
- W2807006263 hasRelatedWork W2807006263 @default.
- W2807006263 hasRelatedWork W788896063 @default.
- W2807006263 hasRelatedWork W2188957685 @default.
- W2807006263 hasVolume "14" @default.
- W2807006263 isParatext "false" @default.
- W2807006263 isRetracted "false" @default.
- W2807006263 magId "2807006263" @default.
- W2807006263 workType "article" @default.