Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807122967> ?p ?o ?g. }
Showing items 1 to 94 of
94
with 100 items per page.
- W2807122967 abstract "In an effort to increase efficiency in the creation of genetically modified mice via ES Cell methodologies, we present an adaptation to the current blastocyst injection protocol. Here we report that a simple rotation of the embryo, and injection through Trans-Inner cell mass (TICM) increased the percentage of chimeric mice from 31% to 50%, with no additional equipment or further specialized training. 26 different inbred clones, and 35 total clones were injected over a period of 9 months. There was no significant difference in either pregnancy rate or recovery rate of embryos between traditional injection techniques and TICM. Therefore, without any major alteration in the injection process and a simple positioning of the blastocyst and injecting through the ICM, releasing the ES cells into the blastocoel cavity can potentially improve the quantity of chimeric production and subsequent germline transmission." @default.
- W2807122967 created "2018-06-13" @default.
- W2807122967 creator A5014910511 @default.
- W2807122967 creator A5031723917 @default.
- W2807122967 creator A5033951135 @default.
- W2807122967 creator A5076332667 @default.
- W2807122967 date "2018-05-29" @default.
- W2807122967 modified "2023-09-26" @default.
- W2807122967 title "Trans-inner Cell Mass Injection of Embryonic Stem Cells Leads to Higher Chimerism Rates" @default.
- W2807122967 cites W1568797227 @default.
- W2807122967 cites W1966697925 @default.
- W2807122967 cites W1968293620 @default.
- W2807122967 cites W2003171404 @default.
- W2807122967 cites W2006844115 @default.
- W2807122967 cites W2008530548 @default.
- W2807122967 cites W2023630351 @default.
- W2807122967 cites W2048418556 @default.
- W2807122967 cites W2052344595 @default.
- W2807122967 cites W2064815984 @default.
- W2807122967 cites W2148508291 @default.
- W2807122967 cites W2623760881 @default.
- W2807122967 doi "https://doi.org/10.3791/56955" @default.
- W2807122967 hasPubMedCentralId "https://www.ncbi.nlm.nih.gov/pmc/articles/6085124" @default.
- W2807122967 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29912196" @default.
- W2807122967 hasPublicationYear "2018" @default.
- W2807122967 type Work @default.
- W2807122967 sameAs 2807122967 @default.
- W2807122967 citedByCount "1" @default.
- W2807122967 countsByYear W28071229672019 @default.
- W2807122967 crossrefType "journal-article" @default.
- W2807122967 hasAuthorship W2807122967A5014910511 @default.
- W2807122967 hasAuthorship W2807122967A5031723917 @default.
- W2807122967 hasAuthorship W2807122967A5033951135 @default.
- W2807122967 hasAuthorship W2807122967A5076332667 @default.
- W2807122967 hasBestOaLocation W28071229672 @default.
- W2807122967 hasConcept C104317684 @default.
- W2807122967 hasConcept C109825262 @default.
- W2807122967 hasConcept C134305767 @default.
- W2807122967 hasConcept C145103041 @default.
- W2807122967 hasConcept C159399396 @default.
- W2807122967 hasConcept C16685009 @default.
- W2807122967 hasConcept C196843134 @default.
- W2807122967 hasConcept C202438428 @default.
- W2807122967 hasConcept C203014093 @default.
- W2807122967 hasConcept C2777804106 @default.
- W2807122967 hasConcept C2778177303 @default.
- W2807122967 hasConcept C28328180 @default.
- W2807122967 hasConcept C30278631 @default.
- W2807122967 hasConcept C54355233 @default.
- W2807122967 hasConcept C62525196 @default.
- W2807122967 hasConcept C71924100 @default.
- W2807122967 hasConcept C86803240 @default.
- W2807122967 hasConcept C87073359 @default.
- W2807122967 hasConcept C95444343 @default.
- W2807122967 hasConceptScore W2807122967C104317684 @default.
- W2807122967 hasConceptScore W2807122967C109825262 @default.
- W2807122967 hasConceptScore W2807122967C134305767 @default.
- W2807122967 hasConceptScore W2807122967C145103041 @default.
- W2807122967 hasConceptScore W2807122967C159399396 @default.
- W2807122967 hasConceptScore W2807122967C16685009 @default.
- W2807122967 hasConceptScore W2807122967C196843134 @default.
- W2807122967 hasConceptScore W2807122967C202438428 @default.
- W2807122967 hasConceptScore W2807122967C203014093 @default.
- W2807122967 hasConceptScore W2807122967C2777804106 @default.
- W2807122967 hasConceptScore W2807122967C2778177303 @default.
- W2807122967 hasConceptScore W2807122967C28328180 @default.
- W2807122967 hasConceptScore W2807122967C30278631 @default.
- W2807122967 hasConceptScore W2807122967C54355233 @default.
- W2807122967 hasConceptScore W2807122967C62525196 @default.
- W2807122967 hasConceptScore W2807122967C71924100 @default.
- W2807122967 hasConceptScore W2807122967C86803240 @default.
- W2807122967 hasConceptScore W2807122967C87073359 @default.
- W2807122967 hasConceptScore W2807122967C95444343 @default.
- W2807122967 hasIssue "135" @default.
- W2807122967 hasLocation W28071229671 @default.
- W2807122967 hasLocation W28071229672 @default.
- W2807122967 hasLocation W28071229673 @default.
- W2807122967 hasLocation W28071229674 @default.
- W2807122967 hasOpenAccess W2807122967 @default.
- W2807122967 hasPrimaryLocation W28071229671 @default.
- W2807122967 hasRelatedWork W1970916168 @default.
- W2807122967 hasRelatedWork W1983702236 @default.
- W2807122967 hasRelatedWork W2033192545 @default.
- W2807122967 hasRelatedWork W2048701533 @default.
- W2807122967 hasRelatedWork W2157843794 @default.
- W2807122967 hasRelatedWork W2223970316 @default.
- W2807122967 hasRelatedWork W2373479018 @default.
- W2807122967 hasRelatedWork W2378094771 @default.
- W2807122967 hasRelatedWork W2380960457 @default.
- W2807122967 hasRelatedWork W3151133888 @default.
- W2807122967 isParatext "false" @default.
- W2807122967 isRetracted "false" @default.
- W2807122967 magId "2807122967" @default.
- W2807122967 workType "article" @default.