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• W2807141738 abstract "Stereotactic Body Radiation Therapy: Spinal Metastasis Optimal fractionation for SBRT for spinal metastasisRoi Dagan & Robert J AmdurRoi DaganRoi Dagan is Assistant Professor of Radiation Oncology at the University of Florida Proton Therapy Institute (USA). He completed his medical and postgraduate training at the University of Florida. His clinical focus includes management of head and neck and breast cancers, and he directs the stereotactic radiotherapy program at the University of Florida Proton Therapy Institute. This includes stereotactic conventional and proton therapy for primary lung tumors, primary and metastatic ocular tumors, and metastatic tumors involving the spine, lungs and liver. His research interests include clinical outcomes of patients managed with stereotactic ablative radiotherapy for oligometastases.Search for more papers by this author & Robert J AmdurRobert J Amdur is Professor of Radiation Oncology at the University of Florida. He currently serves as Residency Program Director and previously served as interim chair of the Radiation Oncology Department. His clinical interests include management of head and neck, CNS, gynecologic and spine tumors. His research has spanned multiple areas including clinical outcomes in head and neck radiotherapy, spine radiosurgery, medical education and biomedical ethics.Search for more papers by this authorPublished Online:9 Jul 2014https://doi.org/10.2217/ebo.13.690AboutSectionsView ArticleView Full TextPDF/EPUB ToolsAdd to favoritesDownload CitationsTrack Citations ShareShare onFacebookTwitterLinkedInReddit View chapterAbstract: Summary Stereotactic body radiation therapy (SBRT) for spinal metastases requires the use of extreme hypofractionation. Both single- and multi-fraction regimens have been used with doses ranging from 10 to 24 Gy in one fraction and from 24 to 35 Gy in three to five fractions. Single-fraction spine SBRT is more convenient for the patient and treatment staff, but spinal cord toxicity may be higher and there may be a higher risk for vertebral compression fracture associated with fractional doses above 20 Gy. No single optimal fractionation scheme appears superior. Patients with tumors encroaching on the epidural space, prior radiotherapy or oligometastases are better suited for multifraction spine SBRT. Regardless of the fractionation scheme used, keeping within the spinal cord tolerance should be the primary planning objective. References1 Heron DE , Rajagopalan MS , Stone B et al. Single-session and multisession CyberKnife radiosurgery for spine metastases-University of Pittsburgh and Georgetown University experience . J. Neurosurg. Spine 17 (1) , 11 – 18 (2012) . Crossref, Medline, Google Scholar2 Kirkpatrick JP , Meyer JJ , Marks LB . The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery . Semin. Radiat. Oncol. 18 (4) , 240 – 243 (2008) . Crossref, Medline, Google Scholar3 Weber PC , Koltai PJ . Chlamydia trachomatis in the etiology of acute otitis media . Ann. Otol. Rhinol. Laryngol. 100 (8) , 616 – 619 (1991) . Crossref, Medline, CAS, Google Scholar4 Wang JZ , Huang Z , Lo SS et al. A generalized linear-quadratic model for radiosurgery, stereotactic body radiation therapy, and high-dose rate brachytherapy . Sci. Transl. Med. 2 (39) , 39ra48 (2010) . Crossref, Medline, Google Scholar5 Park C , Papiez L , Zhang S et al. Universal survival curve and single fraction equivalent dose: useful tools in understanding potency of ablative radiotherapy . Int. J. Radiat. Oncol. Biol. Phys. 70 (3) , 847 – 852 (2008) . Crossref, Medline, Google Scholar6 Finkelstein SE , Timmerman R , McBride WH et al. The confluence of stereotactic ablative radiotherapy and tumor immunology . Clin. Dev. Immunol. 2011 (439752) (2011) . Medline, Google Scholar7 Garcia-Barros M , Paris F , Cordon-Cardo C et al. Tumor response to radiotherapy regulated by endothelial cell apoptosis . Science 300 (5622) , 1155 – 1159 (2003) . Crossref, Medline, CAS, Google Scholar8 Fuks Z , Kolesnick R . Engaging the vascular component of the tumor response . Cancer Cell 8 (2) , 89 – 91 (2005) . Crossref, Medline, CAS, Google Scholar9 Schneider BF , Eberhard DA , Steiner LE . Histopathology of arteriovenous malformations after gamma knife radiosurgery . J. Neurosurg. 87 (3) , 352 – 357 (1997) . Crossref, Medline, CAS, Google Scholar10 Szeifert GT , Timperley WR , Forster DM et al. Histopathological changes in cerebral arteriovenous malformations following Gamma Knife radiosurgery . Prog. Neurol. Surg. 20 , 212 – 219 (2007) . Crossref, Medline, Google Scholar11 Salama JK , Kirkpatrick JP , Yin FF . Stereotactic body radiotherapy treatment of extracranial metastases . Nat. Rev. Clin. Oncol. 9 (11) , 654 – 665 (2012) . Crossref, Medline, CAS, Google Scholar12 Schaue D , Ratikan JA , Iwamoto KS et al. Maximizing tumor immunity with fractionated radiation . Int. J. Radiat. Oncol. Biol. Phys. 83 (4) , 1306 – 1310 (2012) . Crossref, Medline, CAS, Google Scholar13 Yamada Y , Bilsky MH , Lovelock DM et al. High-dose, single-fraction image-guided intensity-modulated radiotherapy for metastatic spinal lesions . Int. J. Radiat. Oncol. Biol. Phys. 71 (2) , 484 – 490 (2008) . Crossref, Medline, Google Scholar14 Lovelock DM , Zhang Z , Jackson A et al. Correlation of local failure with measures of dose insufficiency in the high-dose single-fraction treatment of bony metastases . Int. J. Radiat. Oncol. Biol. Phys. 77 (4) , 1282 – 1287 (2010) . Crossref, Medline, Google Scholar15 Greco C , Zelefsky MJ , Lovelock M et al. Predictors of local control after single-dose stereotactic image-guided intensity-modulated radiotherapy for extracranial metastases . Int. J. Radiat. Oncol. Biol. Phys. 79 (4) , 1151 – 1157 (2011) . Crossref, Medline, Google Scholar16 Gerszten PC , Burton SA , Ozhasoglu C et al. Radiosurgery for spinal metastases: clinical experience in 500 cases from a single institution . Spine (Phila Pa 1976) 32 (2) , 193 – 199 (2007) . Crossref, Medline, Google Scholar17 Amdur RJ , Bennett J , Olivier K et al. A prospective, Phase II study demonstrating the potential value and limitation of radiosurgery for spine metastases . Am. J. Clin. Oncol. 32 (5) , 515 – 520 (2009) . Crossref, Medline, Google Scholar18 Ryu S , Jin R , Jin JY et al. Pain control by image-guided radiosurgery for solitary spinal metastasis . J. Pain Symptom Manage. 35 (3) , 292 – 298 (2008) . Crossref, Medline, Google Scholar19 Garg AK , Shiu AS , Yang J et al. Phase 1/2 trial of single-session stereotactic body radiotherapy for previously unirradiated spinal metastases . Cancer 118 (20) , 5069 – 5077 (2012) . Crossref, Medline, Google Scholar20 Rose PS , Laufer I , Boland PJ et al. Risk of fracture after single fraction image-guided intensity-modulated radiation therapy to spinal metastases . J. Clin. Oncol. 27 (30) , 5075 – 5079 (2009) . Crossref, Medline, Google Scholar21 Cunha MV , Al-Omair A , Atenafu EG et al. Vertebral compression fracture (VCF) after spine stereotactic body radiation therapy (SBRT): analysis of predictive factors . Int. J. Radiat. Oncol. Biol. Phys. 84 (3) , e343 – 349 (2012) . Crossref, Medline, Google Scholar22 Yamada Y , Lovelock DM , Yenice KM et al. Multifractionated image-guided and stereotactic intensity-modulated radiotherapy of paraspinal tumors: a preliminary report . Int. J. Radiat. Oncol. Biol. Phys. 62 (1) , 53 – 61 (2005) . Crossref, Medline, Google Scholar23 Chang EL , Shiu AS , Mendel E et al. Phase I/II study of stereotactic body radiotherapy for spinal metastasis and its pattern of failure . J. Neurosurg. Spine 7 (2) , 151 – 160 (2007) . Crossref, Medline, Google Scholar24 Garg AK , Wang XS , Shiu AS et al. Prospective evaluation of spinal reirradiation by using stereotactic body radiation therapy: the University of Texas MD Anderson Cancer Center experience . Cancer 117 (15) , 3509 – 3516 (2011) . Crossref, Medline, Google Scholar25 Wang XS , Rhines LD , Shiu AS et al. Stereotactic body radiation therapy for management of spinal metastases in patients without spinal cord compression: a Phase 1–2 trial . Lancet Oncol. 13 (4) , 395 – 402 (2012) . Crossref, Google Scholar26 Gill B , Oermann E , Ju A et al. Fiducial-free CyberKnife stereotactic body radiation therapy (SBRT) for single vertebral body metastases: acceptable local control and normal tissue tolerance with 5 fraction approach . Front. Oncol. 2 (39) (2012) . Medline, Google Scholar27 Ahmed KA , Stauder MC , Miller RC et al. Stereotactic body radiation therapy in spinal metastases . Int. J. Radiat. Oncol. Biol. Phys. 82 (5) , e803 – e809 (2012) . Crossref, Medline, Google Scholar28 Laufer I , Iorgulescu JB , Chapman T et al. Local disease control for spinal metastases following “separation surgery” and adjuvant hypofractionated or high-dose single-fraction stereotactic radiosurgery: outcome analysis in 186 patients . J. Neurosurg. Spine 18 (3) , 207 – 214 (2013) . Crossref, Medline, Google Scholar29 Nelson JW , Yoo DS , Sampson JH et al. Stereotactic body radiotherapy for lesions of the spine and paraspinal regions . Int. J. Radiat. Oncol. Biol. Phys. 73 (5) , 1369 – 1375 (2009) . Crossref, Medline, Google ScholarFiguresReferencesRelatedDetails Stereotactic Body Radiation Therapy: Spinal MetastasisMetrics Downloaded 12 times History Published online 9 July 2014 Published in print July 2014 Information© Future Medicine Ltd© Future Medicine LtdPDF download" @default.
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