FRINK Linked Data Fragments server

Matches in SemOpenAlex for { <https://semopenalex.org/work/W2807156577> ?p ?o ?g. }

• W2807156577 endingPage "11497" @default.
• W2807156577 startingPage "11493" @default.
• W2807156577 abstract "Abstract Ischemic heart disease often leads to myocardial infarction and remains the most common cause for death in humans. Although the exact impetus for the infarction remains elusive, a mechanism has been proposed that relates the disease to the observed high cholesterol levels in the body. The mechanism claims that cholesterol crystallizes inside the arterial plaque into needle‐shaped crystals. The crystals puncture the fibrous cap of the plaque, whereby the necrotic contents of the plaque are spilled, subsequently clotting the blood vessels. This hypothesis has not been given sufficient attention partly due to the purported softness of the organic crystals and the common platy habit of the known crystal forms of cholesterol. In this work it is shown that, from hydrophobic solutions that attempt to emulate the plaque contents, a new solid form of cholesterol crystallizes as prisms with mucronate tips, and they are sufficiently strong to puncture a lamb pericardium, which mimics the plaque cap. The properties of the crystals were assessed by mechanical, structural, and crystallographic analyses. The results support the hypothesis that the cholesterol crystals can be considered, at least within the framework of the proposed mechanism, a possible cause of myocardial infarction." @default.
• W2807156577 created "2018-06-13" @default.
• W2807156577 creator A5001482734 @default.
• W2807156577 creator A5003363499 @default.
• W2807156577 creator A5009976096 @default.
• W2807156577 creator A5037851737 @default.
• W2807156577 creator A5044722539 @default.
• W2807156577 creator A5064564309 @default.
• W2807156577 date "2018-07-10" @default.
• W2807156577 modified "2023-10-12" @default.
• W2807156577 title "Mechanical and Crystallographic Analysis of Cholesterol Crystals Puncturing Biological Membranes" @default.
• W2807156577 cites W1949072443 @default.
• W2807156577 cites W1963695670 @default.
• W2807156577 cites W1974400589 @default.
• W2807156577 cites W1977436685 @default.
• W2807156577 cites W1995849206 @default.
• W2807156577 cites W2006222394 @default.
• W2807156577 cites W2007542782 @default.
• W2807156577 cites W2007554344 @default.
• W2807156577 cites W2011173327 @default.
• W2807156577 cites W2013721372 @default.
• W2807156577 cites W2021125117 @default.
• W2807156577 cites W2023593626 @default.
• W2807156577 cites W2028693103 @default.
• W2807156577 cites W2033538708 @default.
• W2807156577 cites W2034435021 @default.
• W2807156577 cites W2036313288 @default.
• W2807156577 cites W2048815642 @default.
• W2807156577 cites W2049444470 @default.
• W2807156577 cites W2050166533 @default.
• W2807156577 cites W2055269249 @default.
• W2807156577 cites W2058614644 @default.
• W2807156577 cites W2070699680 @default.
• W2807156577 cites W2072958209 @default.
• W2807156577 cites W2080225700 @default.
• W2807156577 cites W2088935147 @default.
• W2807156577 cites W2092369579 @default.
• W2807156577 cites W2111612705 @default.
• W2807156577 cites W2120910913 @default.
• W2807156577 cites W2130833397 @default.
• W2807156577 cites W2132402262 @default.
• W2807156577 cites W2132968683 @default.
• W2807156577 cites W2139541473 @default.
• W2807156577 cites W2185829196 @default.
• W2807156577 cites W2340744737 @default.
• W2807156577 cites W2400642605 @default.
• W2807156577 cites W2516046034 @default.
• W2807156577 cites W2555780791 @default.
• W2807156577 cites W4234546218 @default.
• W2807156577 cites W4256475235 @default.
• W2807156577 doi "https://doi.org/10.1002/chem.201802251" @default.
• W2807156577 hasPubMedId "https://pubmed.ncbi.nlm.nih.gov/29877594" @default.
• W2807156577 hasPublicationYear "2018" @default.
• W2807156577 type Work @default.
• W2807156577 sameAs 2807156577 @default.
• W2807156577 citedByCount "7" @default.
• W2807156577 countsByYear W28071565772019 @default.
• W2807156577 countsByYear W28071565772020 @default.
• W2807156577 countsByYear W28071565772022 @default.
• W2807156577 countsByYear W28071565772023 @default.
• W2807156577 crossrefType "journal-article" @default.
• W2807156577 hasAuthorship W2807156577A5001482734 @default.
• W2807156577 hasAuthorship W2807156577A5003363499 @default.
• W2807156577 hasAuthorship W2807156577A5009976096 @default.
• W2807156577 hasAuthorship W2807156577A5037851737 @default.
• W2807156577 hasAuthorship W2807156577A5044722539 @default.
• W2807156577 hasAuthorship W2807156577A5064564309 @default.
• W2807156577 hasConcept C111472728 @default.
• W2807156577 hasConcept C126322002 @default.
• W2807156577 hasConcept C138885662 @default.
• W2807156577 hasConcept C164705383 @default.
• W2807156577 hasConcept C185592680 @default.
• W2807156577 hasConcept C192562407 @default.
• W2807156577 hasConcept C2778163477 @default.
• W2807156577 hasConcept C2778875491 @default.
• W2807156577 hasConcept C500558357 @default.
• W2807156577 hasConcept C71924100 @default.
• W2807156577 hasConcept C8010536 @default.
• W2807156577 hasConcept C89611455 @default.
• W2807156577 hasConceptScore W2807156577C111472728 @default.
• W2807156577 hasConceptScore W2807156577C126322002 @default.
• W2807156577 hasConceptScore W2807156577C138885662 @default.
• W2807156577 hasConceptScore W2807156577C164705383 @default.
• W2807156577 hasConceptScore W2807156577C185592680 @default.
• W2807156577 hasConceptScore W2807156577C192562407 @default.
• W2807156577 hasConceptScore W2807156577C2778163477 @default.
• W2807156577 hasConceptScore W2807156577C2778875491 @default.
• W2807156577 hasConceptScore W2807156577C500558357 @default.
• W2807156577 hasConceptScore W2807156577C71924100 @default.
• W2807156577 hasConceptScore W2807156577C8010536 @default.
• W2807156577 hasConceptScore W2807156577C89611455 @default.
• W2807156577 hasIssue "44" @default.
• W2807156577 hasLocation W28071565771 @default.
• W2807156577 hasLocation W28071565772 @default.
• W2807156577 hasOpenAccess W2807156577 @default.
• W2807156577 hasPrimaryLocation W28071565771 @default.
• W2807156577 hasRelatedWork W146325290 @default.
• W2807156577 hasRelatedWork W1984675410 @default.

• next